Everything that begins must eventually end. This episode of beginnings and endings walks us both backwards and forwards as we take our final stroll down Wisteria Lane.
Alexander is convinced that a lightning strike on St. Peter's Basilica during mass was a sign of God's disapproval; Cesare tries to prove his worth as a military commander; the Pope pressures the reluctant Lucrezia to enter another political marriage.
When Stan catches Steve playing imaginary games with his toys, he decides to take his son down to Mexico to help him become a man. But the trip takes a turn for the worse when Stan and Steve are kidnapped by a drug cartel, and it’s up to Steve to break himself and Stan out of captivity.
When city hall threatens to close Peter's business, he joins the Tea Party and campaigns to shut down the government.
Don attempts to regain his creative spark, but undermines a member of his staff while doing so. Roger pursues some new clients, and in the process, hurts Jane. Betty displays her pettiness when she reveals a distressing secret to Sally.
Marlene wants see a concert but every time she leaves the zoo she becomes a monster!
When Harry's client is acquitted of raping and murdering his ex-girlfriend, the victim's father and brother take the courtroom hostage. Meanwhile, a friend of Cassie's needs help after being in a car accident.
Ma takes up residence in the Penguins Lair. She smothers the penguins with love and they devolve into a bunch of softies, opening the door for Hans to take advantage.
Dan and Amy try to figure out if an Asian-American war hero-cum-governor could be a political threat to Selina. Meanwhile, Selina and Mike prep for her "Meet the Press" interview; and Gary and Amy make a startling discovery about Selina's romantic life.
Jamie meets a distant relative. Daenerys receives an invitation to the House of the Undying. Theon leads a search party. Jon loses his way in the wilderness. Cersei counsels Sansa.
Usher performs "Scream" and "Climax" Skits include: Nasaflu, Wilson High School Alternative Prom, ESPN Classic, The 100th Digital Short, 2012 Funkytown Debate, Broadway Sizzle, Vince and Angela’s 25th Anniversary
Korra and the Fire Ferrets are in the pro-bending championship, but will the Equalists allow the game to go on?
The Team and the Justice League continue to hunt the Kroloteans that have invaded Earth—but the aliens have help from an extremely unexpected source.
The guys talk about their favorite tanks, fish, and pranks from season 1, including behind the scenes stories and never before seen footage from all their favorite tanks.
When Freddie gets a new job at the Pear Store, Sam, who is employed with him, accidentally ruins it. Meanwhile, Spencer makes a fire for the 18th time and because of their tiredness, the fire department is done with the Shays and to apologize, Spencer brings a batch of brownies to the station. Unfortunately, the vengeful staff makes him volunteer at the fire station, which leads to another fire, this time at the station. Also, Carly meets a boy at the the Pear Store named Trey and becomes obsessed to get him to ask her out.
Captain Hook's Mama want him to find a treasure, so he takes some from Jake and the crew.