Lucas and Peyton's wedding day finally arrives, bringing some surprise guests along with it. Haley finds herself playing an unexpected role in the ceremony, as Skills and Brooke try to control Jamie and Nick. Meanwhile, Nathan continues to hope to be drafted into the NBA.
House and the team are intrigued by Scott, a man whose left brain and right brain operate independently, leaving him with two distinct personalities and no control over some of his actions. As the two sides of Scotts brain struggle for dominance, his warring personalities make it increasingly difficult for the team to figure out what is causing the unique problem. The team is forced to use some unusual methods to get him to cooperate with their necessary testing. Meanwhile, when House refuses to make an appearance in the clinic, Cuddy takes an unconventional approach to force House to make up the time with a particular patient.
The guys' plan to work over the summer at the North Pole makes Penny revaluate her feelings for Leonard.
Ted is trying to find a new job, and when an old acquaintance tries to help nothing goes as planned. Barney tries to smooth talk his way out of a ticket.
To prove her independence, Serena refuses to leave jail with her mother or her grandmother. Rufus is furious with Lily for having Serena arrested.
After falling into a coma during an investigation, Allison's spirit finds it's way into the body of a man named Todd Emory. Joe and the kids have to adjust to living with Allison's spirit in the body of Todd, who insists on living with them.
Backroad Pizza (Santa Fe, NM), Jamaica Gates Caribbean Cuisine (Arlington, TX), Westside Drive-In (Boise, ID) Guy Fieri uncovers some unexpected joints the locals love: In Boise, ID, a 50-year-old drive-in where you can order prime rib; In Santa Fe, NM, a pizza joint where they'll top your pie with green chilis and Jamaican cooking in Forth Worth,TX.
Alan and Chelsea become best buds, and Charlie decides to take advantage of the situation.
Castle and Beckett investigate the murder of a missing plastic surgeon who is found dead in the front seat of his car after a week of being parked curbside. As they delve into the twisted world of surgery obsessed patients and secret operations, Castle experiences a fatherly rite of passage as Alexis attends her first prom. And while looking into Becketts past, he unearths information that could end his relationship with her forever.
Walt and Hank get into a heated argument at a party. Skyler opens up to her boss. Jane hides her relationship with Jesse from her father.
Bree goes to extremes to hide her true intentions from Orson, while Susan and Jackson put on an act for the authorities. Lynette is shocked at the lengths Tom will go to in order to look younger, and Katherine masks the truth from Mike, afraid to lose him. Meanwhile, Dave is on edge when he learns a key witness to his misdeeds surfaces.
When several dirty bombs are found on American soil, The Unit is deployed to find and diffuse. On the home front, the wives prepare for a wedding and a possible divorce.
Matchmaking begins in earnest as Cromwell schemes to secure the Reformation by marrying Henry to a Protestant wife - but the king's marital reputation precedes him the condition of Henry's wounded leg turns life-threatening.
Peter learns from a psychic through a palm reading that he had a fascinating past life in the 17th century as Griffin Peterson, a dignified English gentleman who vied for the love of Lady Redbush in the newly founded American colony of Quahog.
A Pink Man tries to blow up the moon. Features a full-fledged orchestral score.
A building collapses on one of Mary's witnesses, leaving him exposed to outside threats, so Mary has to risk her life in order to keep her witness safe.
Gently and Bacchus investigate the murder of a young woman whose body is found in a local church. They discover that the girl was a 'Fox', a waitress working at the first hostess club in Newcastle.
Marge and Lisa visit the nail salon where they engage in a spirited debate as to whether a woman can be smart, powerful and beautiful all at the same time and spin four tales of famous women featuring famous Springfield faces: Selma as Queen Elizabeth I, Lisa as Snow White, Marge as Lady Macbeth and Maggie as Howard Roark, the idealistic architect protagonist from Ayn Rand’s The Fountainhead.