Mike hooks up with the tar rigging crew on the oldest active merchant ship in the world, the Star of India in San Diego. Then, Mike looks back at some of the dirtiest tools he's used, all which make life simpler for the rest of us.
Annie and Ethan get paired up for a class project where they must take care of a baby. This time together forces them to see each other in a new light. At Silver's half-birthday party, Silver and Dixon continue to get closer. Meanwhile, Harry and Debbie must deal with Harry's past when Tracy tells Harry that she's hired an investigator to find their son. Elsewhere, Ryan tries to cope with Kelly leaving and decides to try online dating.
A sleep study goes awry; a little girl's imaginary friend becomes a babysitter's problem; partygoers stray into a quarantined area; a radio show about unexplained phenomena gets an unlikely visitor.
Derek plans to drop of out of school to be with Sally in Vancouver.
Jay and Sherry have an older son they wanted to keep at home, so the basement unit of their house is perfect. Although they're all together, the layout of the house has major issues - the kitchen is tiny and the bedrooms aren't private. The family doesn't know what to do. Designer Hilary and Realtor David are ready to help. Hilary and her team renovate the house to make it function for everyone. David will search for houses that will convince the family to move. In the end, Jay and Sherry will have to choose what's best for their family. Should they love their house again? Or should they list it?
Heidi tries to reach out to Lauren. Meanwhile Audrina has a date, but what will Justin say to that?
Trouble is brewing at Spellman's Magical Museum of the Circus when a group of people join hands and block the entrance the the museum... but they let Sarah Jane in, what is this mystery all about?
Denny is arrested on concealed-weapon charges after shooting a man who tried to rob him and Jerry. Meanwhile, a case gets personal for Alan when he tries to help a sex surrogate in a custody battle for her daughter.
John and Derek infiltrate a military academy in order to protect an integral member of the future resistance. Meanwhile, Weaver’s first assignment for Ellison takes an interesting turn of events when he discovers a specter from his own past.
Nadine's Restaurant (Pittsburgh, Pa.) •Casamento's Restaurant (New Orleans, La.) • Big Mama's Kitchen & Catering (Omaha, Neb.) Guy Fieri uncovers three joints puttin' a piece of history on the table: In New Orleans, an oyster bar where nothin's changed since 1919 and the deep fried oysters are still hand-shucked; in Pittsburg, a neighborhood 'dive' where Mama Nadine's dishin' up roast beef smothered in gravy and in Nebraska, Big Mama's cookin' her Grandma's soul food in an old school cafeteria.
Lincoln takes members of the team to Las Vegas where Sucre gets an indecent proposal. Sara learns about Michael’s condition, and Roland pushes his luck too far. Gretchen teams up with T-Bag who makes an offer to Michael he cannot refuse. Meanwhile, the secrets in Whistler’s bird book are finally revealed.
When Stella's babysitter cancels, a night out turns into the gang hanging out at her place, and Ted talks up New Jersey... until he learns Stella wants him to move there after marriage.
Chuck needs to go undercover to seduce a woman named Sasha Banachek, so an old school spy named Roan Montgomery is assigned as his mentor. Meanwhile, Captain Awesome finds himself in need of some relationship advice, and and turns to Morgan, and Lester faces his first problems as assistant manager.
Sheldon creates a monster when he introduces Penny to online gaming.
Alan, Jake, and Charlie all decide to try new things: Alan is dating more than one woman, Charlie learns to cook, and Jake experiments with beer.
Peter travels to the future and adopts a dangerous ability in order to try to save the world. Meanwhile, Mohinder struggles with his continuing evolution from the formula, and Hiro and Ando re-unite with an old enemy.
Delko's deepest secrets are threatened to be exposed when the daughter of his therapist is killed. The team rushes to find the killer before this happens.
A 10-year-old boy is found dead on his bedroom floor. Dr. Norma Jean Farley, one of Dr. G's pathology fellows, volunteers for the case. The boy had been taking Ritalin for ADHD and he had asthma, but Dr. Farley must also rule out child abuse. When the cause of death proves elusive, Dr. Farley seeks Dr. G's help, and both doctors are shocked when the tragic cause of death is revealed. A 10-year-old girl is struck by lightning, and is subsequently left brain dead with no hope for recovery. The family makes the decision to donate their daughter's organs. Dr. G must decide if she can perform a successful investigation without the girl's vital organs.