Caitlin falls in love with two different guys named Vince and Blake at the same time. Meanwhile, an old bickering couple get a new job at Burger Mcflipsters with Wyatt (Harvey Atkin guest stars as George Bickerson.)
The biggest pot in televised poker history on this episode of High Stakes Poker that features Antonio Esfandiari, Sammy Farha, David Benyamine, Patrik Antonius, Guy Laliberte, Jamie Gold, Barry Greenstein, and Doyle Brunson.
Charlie writes a children’s song and finds success as Charlie Waffles. The children love him and the mothers seem to as well. Charlie's new found fame irritates Alan.
Raj's parents set him up on a blind date, but just when he discovers he can talk to her, she shows interest in Sheldon.
Chuck must learn to balance a real love life with his cover love life when he meets a charming young woman by the name of Lou. At the same time, his relationship with Sarah gets interesting when the duo must explain their sexual relations with Ellie and Captain Awesome on a double date. Meanwhile, there is trouble when someone is using truth poison in order to retrieve codes for nuclear facilities.
Nancy has another full week of trouble to deal with and Doug isn't helping. Heylia teaches Celia.
Marshall awaits his bar exam results; Ted introduces his latest girlfriend to the gang, who all see the flaw that Ted has missed
Susan jeopardizes Michael's life as she puts her own escape plan into motion. Whistler's past catches up to his girlfriend.The Company goes after Lincoln and Sucre. Justice prevails for Mahone. And Lechero sheds light into an empty tunnel.
A family is in Miami vacationing from Canada when one of their sons is killed.
When Darnell confronts Maya about not dealing with her recent loss he learns shocking news that Maya has been taking pills to help her deal with it. Meanwhile, At an Erykah Badu concert with Joan, Lynn's manager informs her about a record label wanting to sign her. William also fears that his sex life will change after Monica has the baby after receiving information from Darnell about how a womens body is after she gives birth.
The events of the "missing four months" are explored. Maya and Alejandro must go on the run, it is explained how Peter ended up in Ireland and what happened to Nathan, Nikki, and D.L.
Lynette's sisters Lydia and Lucy come to visit. While having dinner with Susan and Mike, Bree and Orson realize they share different views on whether their newborn baby should be circumcised. On a boat, Victor confronts Gaby about her affair with Carlos and she throws him into the ocean. Later, Bree informs Susan that she thinks Mike is addicted to drugs.
Milhouse stays with the Simpsons when his parents remarry each other and honeymoon on a cruise ship. But when his parents are knocked overboard and lost at sea, Milhouse decides to grow up and be a man.
Dethklok enters the fashion industry to promote their new clothing line, and in the the process experiences the brutality of negative body image, dieting, and bulimia.
Dexter manages to get Doakes off his back. He devises a plan to get the police in another direction. Lila and Dex's relationship intensifies, and he has some interaction with Rita and the kids.
The Walkers unite as Justin's addiction hits an all-time low. Kitty and Robert build new plans for their future.
Presumed dead, Lois returns from the wilderness and names Stewie as her killer. On the lookout for Stewie, Joe leads a manhunt around Quahog. Desperate to stop Stewie, Lois realizes what she must do.
When the family goes out to a restaurant where the food is cooked at the table Cotton throws a tantrum and gets into a fight with the chef. The fight leaves Cotton near death in the hospital.