Charlie's young, hot girlfriend takes him to a new club. She invites Alan to meet one of her friends but the men are shocked to learn that they are considered as being "old".
Eddie and Lund protect a 13 year old gang member from a rival gang, and Eddie reunites with the foster family who took care of him after his mother died.
Brian McAfee is a newly-divorced father of four children living a lonely, isolated life in Alaska. Brokenhearted and bewildered, Brian has shut himself off from the world and even his own children in many ways. He doesn't know any of his neighbors or his kids' teachers. He's uncomfortable doing girly things with his daughters, which has left a big gap in their relationship with him, especially for the oldest, Ellie (9). Brian's also baffled by his son's troubles with schoolwork, their house is a disaster, and all four kids have serious behavior problems because there's no discipline at home.
While Russell has a hot new date, Audrey bets Jeff that he can't score a phone number from a younger woman and gives him a night without his wedding ring to try.
Action continues on High Stakes Poker as Sammy Farha, Brian Townsend, Todd Brunson, Paul Wasicka, Barry Greenstein, Jennifer Harman, Erick Lindgren, and Eli Elezra continue to battle in this $300/$600 No-Limit Hold'em cash game.
George's curiosity about bones leads him to climb the dinosaur skeleton at the museum but he ends up falling off and breaking his leg. George must wear a cast for a few weeks and stay home. Hundley stays with him as his monkey sitter. George begins in a wheelchair and does not know how to use it, but Hundley teaches him how to navigate around the furniture in his apartment. Soon, George can walk on crutches and Hundley helps him out in the same way. Later, once George can walk on his cast, he goes to places like the park with Hundley.
Despite Pablo and Kris protests, Matt and Jean consider selling Wildfire to help Raintree stay afloat. Meanwhile, Gillian and Junior end up bonding at Bobby's club one night while Matt and Kris are busy.
While Jack looks for Gredenko and tries to save Josh, White House intrigue deepens.
When Ms. Morello is off of school for the day, Chris and Greg cut school to go see Ghostbusters. Drew and Tonya aren't happy that Rochelle is going to help out at their school. Julius renews his license at DMV.
Peter learns that he and Claude may have been betrayed. Matt's reunited with the radioactive Ted Sprague and Hana Gitelman a woman with "wireless" mental abilities. Hiro makes a tough choice about his mission. Claire can no longer hold back her anger towards HRG.
Lily gets asked to play in an off-off-off-off-broadway play, and the gang shows up to support her. Ted and Robin get hung up on what each kept from their past relationships. Barney performs his own play to prove a point to Lily.
Michael and Sara request Henry Pope's help to retrieve the information that will topple The Company.Mahone pins down an escapee. Sucre discovers a new threat while hitchhiking to reunite with Maricruz. T-Bag brings the Hollander family to his home.
A documentary filmmaker who interviewed a group of Springfield schoolchildren 32 years ago has followed up at eight-year intervals to film how their lives have unfolded.
All of Wisteria Lane gathers at Pizzeria Scavo for the grand opening event, while one resident meets an untimely fate and another accepts a marriage proposal.
A beautiful young woman asks Harry to help her recover some stolen money. Before long, Dresden discovers a connection between this case and a dark, supernatural evil, and that his lovely client has been hiding something.
When a bully harasses Chris, Peter goes to his defense, but ends up beating him up. Peter realizes bullying is fun and begins to bully everyone in the house. Finally, Chris stands up to Peter and beats him senseless. Meanwhile, Stewie goes out without sunscreen and becomes obsessed with getting a tan. After Brian leaves him in the tanning booth for six hours, Stewie gets sunburned and fears he has cancer. While waiting for the results of his cancer screening, Stewie begins to live his life as if he had only days to live and drives Brian crazy with his demands.
Vorenus receives orders to plunge Rome into a bloodbath the likes that have not been seen since the dictatorship of Sulla. Octavia reveals her secret to Atia, and the armies of the Liberators and the Caesarians clash for the last time, with the fate of Republic in the balance.
After accidentally punching Drake in school, Eric becomes very popular. Meanwhile, Josh thinks that Mindy has a new boyfriend.