Drake has taken advantage of Josh for the last time and Josh decides that he is done dealing with Drake. Drake says he's fine with this, but when Josh's life improves and Drake's goes down the drain this rocker begins crooning a different tune.
The Sagittarons allege that a doctor is discriminating against them. As Helo investigates, he becomes concerned that the doctor may even be murdering patients. Meanwhile, Athena unwittingly brings Hera to the doctor for treatment.
The girls attend a movie premiere sponsored by Shane's underwear campaign. Papi teaches Helena and Alice how to play poker for a high-stakes private game hosted by a high-profile female gambler. Bette disagrees with Tina about Angelica's education, and goes on a date with Jodi. Meanwhile, Phyllis is having trouble letting go of Alice.
Lisa pretends to be Native American for multicultural day at school. Meanwhile, Bart finds love with an older woman.
Ian proposes to Susan. The Scavo pizzeria prepares for its grand opening. Mike visits a hypnotherapist in hopes of remembering Monique. Gabrielle's romantically interested in a lawyer, but he's working for Zach who wants her for himself. Bree is hospitalized after a fall, after being tricked to climb on a ladder to retrieve Monique's teeth.
A series of ritualistic murders starts to look a lot like werewolves so Harry, of course, gets dragged in. Thing is, it looks like the lycanthropes aren't the killers... they're the victims.
After Peters dad, Francis, dies, Thelma tells him that his real father actually lives in Ireland. So Peter and Brian decide to head there in search of his father, who ends up being the town drunk. They decide to play a drinking game to prove his paternity. Meanwhile, Stewie acts out and Lois spanks him. Realizing that he likes being spanked, Stewie does whatever he can to get into trouble.
When Señor Senior Junior breaks Shego out of prison to help him get his father a great birthday present, it's up to Kim and Ron to stop them. Meanwhile, Kim urges Ron to get a job after he uses coupons on their date.
Kim investigates a string of celebrity robberies, but comes up empty-handed. Meanwhile, the tweebs enter Middleton High School as freshmen. Ashley Tisdale guest stars.
Ron offers Wade advice on how to woo Monique, but when it backfires, the young supergenius creates a Cupid Ray. Unfortunately, the device falls into the hands of Senor Senior Senior, who uses it to help Junior seduce all the women in the world.
Ron steals Kim's supersuit to use in the upcoming football game. Meanwhile, Professor Dementor becomes jealous of the suit and devises a system to control it.
Lightning Lad resigns from the Legion to join a new team, but soon finds himself caught in a conflict of interest when the two teams end up opposing each other.
The Bat Team goes up against an unstoppable thief who knows their every move.
When Rev and Lexi tamper with Tech's X3000 Automated Weapon System mistakening it for a video game, Melvin the Martian comes to Acmetropolis to destroy it after his spacecraft was hit by a missile from Tech's invention. When Melvin threatens to shrink the planet, Lexi admits she tampered with Tech's invention and Melvin orders that Lexi be handed over to him in 24 Hours. Can the Loonatics find a way to thwart Melvin before Acmetropolis becomes the only planetary location to be "hard to find on any map."
In search of some of the world's best shellfish, Andreas travels to Frøya in South Trøndelag in Norway. He prepares appetizers, delicious fried scallops and makes Norwegian-style sushi using ingredients straight from the Norwegian sea.
Eight years after his wife Helen mysteriously disappeared, Nick Cutter and a team of several others investigate reports of a large animal in the Forest of Dean, and discover that mysterious Anomalies in time and space are appearing and allowing prehistoric creatures to cross into the present day.
Cellphones: Suzie and Ned try to keep their long-distance relationship, by talking in between classes. Moze gets a new phone she has no clue how to use. Cookie wears a jacket covered in 33 cellphones in attempt to win a Mustang Convertible from a local radio station.Woodshop: Ned and Cookie blow up the art room, and have to switch to woodshop. Moze is entering a woodshop competition. Ned keeps overhearing Moze and thinks she is talking about her feelings for him. Cookie is on the run from a killer saw named "Christine".
Johnny and Dukey catch rainy day boredom, and use one of the sisters' devices, thinking that it is an inter-dimensional travel machine, and go into a land known as Johnnia.
Johnny and Dukey must rescue Susan from Bling-Bling Boy in the forms of Johnny X and Super Pooch. Little do they know she doesn't want to be rescued, as Bling-Bling Boy has taken her on a cruise bot with a swimming pool, movie theater, anti-gravity chamber, video arcade, and her favorite restaurants among other luxuries.