When a lab accident transforms Max Dillon into supervillain Electro, he demands that Dr. Martha Connors find a cure as Spider-Man works to stop him.
The boys and Candace hatch a plot to reunite their mom and dad's favorite band for a wedding anniversary concert.
To his disappointment, Hopper wakes up to the same day although the case had been cleared the night before. He decides to take a break for two weeks only to learn the case has become even more mixed up.
While being pursued by the Enforcers, Spider-Man has to protect Norman Osborn from the vengeful supervillain Vulture.
Killface and Simon attempt to repair the burnt couplings on the Annihilatrix, while Stan and Taquil attempt an escape from their shot-down plane. Sinn and Val ask Watley to kill Antagone (due to increasing strains on their relationships with Antagone). Meanwhile, Wendell is sent by Xander to kill the giant ant baby. Both Wendell and Watley inadvertently fall in love with Antagone.
Kate and Paul discuss her input into his life after discussing Rosie.
More friction arises, this time over Lewis' birthday party. Charlotte takes control and drives Rikki away from the party. However, things go out of hand and it is up to her to save the day.
Ethan and Cowboy are detained in Beijing when 50 bags of heroin are found in their luggage.
Juliet receives an unwelcome visit from someone from her past and is given orders to track down Charlotte and Faraday in order to stop them from completing their mission -- by any means necessary. Meanwhile, Ben offers Locke an enticing deal.
Gene and Alex discover that a notorious pimp and drug dealer has a major firearms deal in the pipeline. In an attempt to locate him, the team go undercover in a gay club, and Ray goes beyond the call of duty to get his man.
Sheppard returns to Atlantis after a mission and finds the city abandoned, all systems dead -- and instead of ocean, sand dunes as far as the eye can see.
When a skeletal corpse falls to the stage during a performance, Murdoch discovers not only a sinister murder plot, but Brackenreid’s secret love for the theatre.
With Jake's new look on life, Amy isn't so sure she likes it but Paul tries to bring her round to see him as a new man she can get used to.
With Ash acquiring the Cobble Badge, our heroes decide to spend the night in Veilstone City before heading out. Reggie takes the group to a park with several meteoric stones lie. However, Team Galactic appears and try to steal them for their world domination plans.
A plan to mellow out Mr. Herriman backfires when conditions at the house quickly deteriorate.
Both teams sell works of art by artists they have selected.