Sawyer's wound becomes life-threatening as he, Michael and Jin make their way through the interior of the island with the tail section survivors. Meanwhile, Shannon is once again haunted by visions of Walt.
Cartman suffers from a mysterious and sudden on-set of the disease, Gingervitus. Sick and tired of being ripped-on because he now has red hair, light skin and freckles, he rallies all ginger kids everywhere to fight against discrimination.
Horatio Caine follows Henry Darius to New York so that he can keep his promise to a young boy in Miami, but by the time he and Mac are able to locate Darius he has disappeared again, leaving behind six more bodies. The crossover starts on CSI: Miami S04E07 Felony Flight (I).
Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
The team investigates the killing of a single mother and the abduction of her child.
An old girlfriend of Joey's threatens to release an embarrassing tape. To prevent this from happening he must apologize to her on "The Ellen DeGeneres Show." Bobbie celebrates her 40th birthday.
Jimmy begins teaching the neighborhood kids different things that their fathers can't, and makes a little money on the side doing it.
Larkin barely survives a car crash and the fate of her unborn baby is unknown. Larkin gets picked up by a stranger in a pick-up but she soon becomes suspicious of his motives. Meanwhile, Mariel tries to reconnect with Jesse.
Captain Hero and Wooldoor battle over Unusually Flexible Girl, and Foxxy has a run-in with Foxxy 5.
When the supercomputer's uranium power source begins to fail, Xana is forced to possess a local criminal named Peter Duncan to replace it. The supercomputer's periodic shutdowns threaten not only Xana, but also Aelita, whose heart stops beating with each shutdown.
On 23 March 1994, Aeroflot Flight 593 is en route to Hong Kong, when it stalls and crashes, killing all 75 people on board. The pilot's 15-year-old son accidentally disabled the autopilot while in the captain's seat, causing the aircraft to bank heavily to the right, inducing the stall.
Sean has feelings for Nikki Moretti. Quentin goes after Julia and she welcomes his attention. Christian has a down-syndrome patient who wants to look like the rest of his family. Christian meets with his birth mother again.
Denny is called to defend a man who raped and killed a 13-year-old girl, but decides he'd rather go to jail than spend his days defending murderers. Meanwhile, Alan must face his fear of clowns and Shirley dumps a bizarre bestiality case on Denise.
After the bones of a boy who disappeared in 1978 are found at a playground, Stabler, still visibly recovering from a recent gunshot wound, teams up with Vizcarrando to determine the boy's identity, which leads them to a cold case involving four missing Puerto Rican boys that were never found.
When Michael and Jan try to nail down a potential new client, Christian, by taking him out to Chili's, Michael surprises everyone with what - or who - he does. Meanwhile, back at the office, Jim finds a semi-autobiographical script that Michael has written called Threat Level: Midnight, and he, Pam, Kevin, and the rest of the Dunder-Mifflin workers have a great time acting it out. Later that night, Pam and Jim share their first unofficial date, complete with dinner (a sandwich), candlelight, and Dwight's pathetic fireworks display.
After a construction worker is killed by insects burrowing into his brain, Sam and Dean investigate the town's history and find that the new housing development is being built on sacred Indian land. The Indians put a curse on the land after their reservation had been ravished and destroyed. Sam and Dean must find a way to survive and kill the deadly swarm of bees, locusts, spiders and beetles.
Booth asks Brennan to help locate and identify the remains of a six-year-old boy, Charlie, who went missing from a local park.
Lies between a father and son may prevent House and his team from saving their patient.
When her former boyfriend visits and reveals an amazing success, Rory begins rethinking the choices she's made with her life.
When bodies of two hired assassins are delivered to the NCIS team, Ziva & Tony go undercover assuming the victim's identities in order to find the person who hired the assassins for their mission. While working on the case, Ziva & Tony spend some quality time in a luxury hotel and the attraction between them arises. Gibbs discovers that his team is not the only one working on the case.