Ephram discovers that Bright cheated on Hannah and confronts him about it. Irv takes Edna along on his book tour, where they meet his daughter Cassie. Reid is faced with expulsion from medical school for cheating on an exam. Harold confesses to Andy that he neglected to report Rose's cancer on the adoption application. Ephram tells Amy what happened with Bright, prompting her to confront him and force him to admit the truth to Hannah.
A cruise ship that is docked in Miami is the scene for a double murder. The team investigates the long list of potential suspects but soon find that the list is dramatically decreased when the CSI's find a large amount of money is missing from the victim's stateroom. Horatio and Marisol's relationship evolves.
Breanna's Uncle Kevin flies in from Baltimore to try selling his line of hair-care products to L.A. salons; Breanna refuses to let Arnaz bring any of his dates into the house.
Joan cuts loose two of the men she's dating when she develops feelings for an NBA player. A traumatic event lands Toni behind bars.
Mona is taking her break-up with Chase out on everyone, only to realize that she's also putting her professional career in jeopardy. Dee Dee's newly signed client is married but when she suspects he's having an affair she is faced with a moral dilemma. Meanwhile, Phyllis and Big Dee Dee assume the girls are planning a big Mother's Day celebration, since neither has suggested plans to celebrate.
Vicki and Aaron Newton are separated, with joint custody of their two sons, Aaron (12) and Kobe (5). Though the boys are angels for Dad, young Kobe saves his worst behavior for Mom. He is violent and destructive -- hitting, kicking, slapping, punching and swearing. He even throws rocks at Jo's head. Aaron isn't physically aggressive, but he does talk back to his mother. For the first time, Jo Frost observes life in two homes to hone her recommendations for each parent. But can she get them to collaborate on their child-rearing techniques?
When a serial dog killer starts stalking local parks, the team are reluctantly forced into taking on the case.
While attempting to return some personal effects Dr. Macy makes a startling discovery. Jordan and Lu butt heads over the morgue janitor and Lily prepares for the wedding.
Instead of getting a job, Bobby and Joseph discover that they can make more money, and look cooler, by hanging out on street corners and begging.
Bill and Roman's disagreements result in lawsuits from both sides as well as unwanted houseguests from the compound. Sarah learns about her family's history from her grandmother and Joey confides in Barb.
Gabrielle and Carlos are shocked when the father of their baby shows up to take the baby back. Cops and a lawyer arrive to a house on Wisteria Lane. Lynette tries to help Ed heat up his sex life. Meanwhile, Karl decides to break up with Edie, as Edie has no idea that Susan is the "other woman." Edie causes a fight to break out in a bar, after she trips a waitress. Lastly, Bree is taken a step forward to help Peter when she finds out how bad his other addiction is.
The family attends "Stab-A-Lot: The Itchy and Scratchy Musical." The musical's director is a graduate of Springfield Elementary and Principal Skinner puts his foot in mouth when he makes sexist comments about her education and that of women in general. He tries to make the situation better, but only buries himself deeper and deeper until he is fired and replaced by Women's Educational Expert Melanie Upfoot. The first thing she does is split the school into girls and the boys. Lisa dislikes the way girls are being taught math and she ventures over to the boy's side of the school in search of a challenge. Disguising herself as Jake Boyman she starts attending the boy's school but while she finds the math problems more interesting, it is being a boy that is a greater challenge.
David and Carlos are still investigating the poison that is affecting Charringa's lemon crops in Florida, before the United States decide to bomb Cuba. Jill, on the other hand, asks Mayko to contact all the other labs using the same stem cells from Korea to let them know a retrovirus is in that strain. Bob offers to verify all the steps one more time with her and see if her findings are correct. Simon Jessup finding that Glenn responds to all the stimuli suggests that he undergoes brain surgery.
Huff gets an unexpected visit from his father. Teddy ends up meeting a very attractive young lady while down at the beach. Izzy finds herself arrested on a DUI charge. Beth decides that she will host a meeting of Paula's prayer group. Russell tracks down his young client, who is at a drug house, and then ends up joining in the festivities.
Vito considers starting a new life in New Hampshire, while Anthony continues his pursuit of revenge against Junior.
Addison's patient is a Catholic mother of seven. Addison gets in trouble after learning that the patient's husband won't use contraceptives. Derek treats a divorce attorney who asks if Derek is in need of her services. While Izzie and George are talking about their personal lives they "overhear" part of Derek's conversation with the divorce attorney who calls herself one of Seattle's best. Alex gets in trouble with Addison yet again for not being able to keep his mouth shut when other people think he should. A legendary jazz musician refuses to see medical reason. The musician is Burke's musical hero. Finn makes Meredith breakfast.
Brian's gay cousin Jasper visits the Griffin house and announces that he is engaged to his partner and wants to be married at their house. When Mayor West bans gay marriage in an effort to cover up and bring attention away from a scandal of his own, Brian resorts to hostile actions to try to change the Mayor's mind. Lois and Peter question their view towards gay marriage while Chris joins the "Young Republicans" Club to impress a girl.
Set in the 1960s, this British medical drama follows the staff and patients of St Aidan's Royal Free Hospital.