J Street has become an Atavus hybrid, Renee rushes to locate an antidote.
Eric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
Dr. John Becker goes through his daily routine of being a doctor, stopping at his favorite diner, and other various situations, all the while hating life and everything around him.
As his high school reunion approaches, Doug worries that Carrie's new hairdo will make her look like a librarian, rather than his usually sexy wife. Hoping to show Carrie off in front of his former classmates, Doug tries to find a way to tell her that he hates her bun without hurting her feelings. Meanwhile, Spence informs the guys that he's nervous about seeing one of his old teachers because he never called her back after the two shared an intimate encounter.
Dar faces his biggest test yet in his struggle to defeat the Lord of Darkness.
After her break-up with Aaron, Kim agrees to join Stevie in trying a speed-dating service. Meanwhile, Nikki works at Andell's club and catches Professor Oglevee on a date with another woman who turns out to be married. While on a date, Stevie frets over the fact that she doesn't act very feminine.
Joan engages in surprisingly risky behavior after she begins dating a younger man, Chris. However, her friends urge her to re-consider the relationship after she inadvertently takes ecstasy at a night club. Meanwhile, Toni hires William as her attorney and tries to monopolize all of his time with trivial matters.
Ally and Victor return from their Bermuda trip. Ally feels their relationship is in crisis because they weren't able to connect without Maddie around. Victor is being sued by his former girlfriend for breach of contract. Ally discovers that Victor is a painter and never told her. She's angry, but not as angry as when she sees his painting of her with cellulite. Nelle and Wilson team up against a woman who was blackmailing their client in order not to come public with a tape of their lovemaking. Richard obsesses over Liza and has Claire do the talking for him through a hearing device, afraid she's going to turn him down - and even more afraid she'll say yes to him.
Angel's hotel is infested with demonic slugscreated by the spell he used to alter Sahjhan.
Zorak has set up a booth were children give him money to beat them up. Unfortunately, the business has been taken over by Butch.
The League aid the Justice Guild against their arch-nemeses while trying to unravel the secrets of the Guild's world.
Hank learns that the incident estranging Dale from his cowboy father was a cover to keep him in the dark about Dad being in the closet.
An embattled psychiatrist probes the boys' naughty behavior patterns in a session framed by flashbacks to past episodes.
When a wealthy publisher is murdered to prevent him from exposing an elaborate confidence game that enveloped him, his company and one of his editors, Goren and Eames run their own con to extract a confession from the killer.
When the murder of a city auditor and his family seems too perfect, Goren and Eames turn their attention towards law enforcement personnel after learning that the auditor was investigating a number of former cops upon suspicion of double-dipping.
Percy takes off his glasses to make himself look young again; Olie and Pollie get roles in a school play; a robot helps Olie and his family clean up a mess.
A new student, Laticia Bowers, comes to Lucky Junior High. Her quirky behavior and the fact that she's a mortician's daughter makes her an outcast and target of gossip with the rest of the students. When Ginger and her pals accept her as a friend, will they get Courtney and the "dominant social group" to go to a party at her funeral home house? Meanwhile, Carl and Hoodsey go to Brandon's birthday party.
Soames continues to try and track down where, and with whom, Irene is. Winifred gets the surprise of her life when her husband returns out of the blue. Holly and Val announce they are married and will be moving to South Africa. Soames married Annette and finally he gets a child, but he also loses someone close to him.
Inspired by a cartoonist who speaks at the school as part of a career day assembly, Bart creates a comic book series based on Homer and his anger problems, which turns into a popular Internet cartoon series called Angry Dad. Homer finds out about this and is at first outraged, but after talking to his family, he decides to try to become a less angry person.
Ruth continues to help an injured Nikolai recover, but her patience is tested when she discovers just how he broke his legs. Brenda's escapades help her to write, but her feelings about being engaged grow more muddled--especially after Billy's release from the hospital.