When Hank and Dale find more interest in the activities of the other's son, Dale concludes he's not Joseph's father--and that an alien is.
While on a case to track the activities of Khasinau, a.k.a. "The Man," Sydney runs into her ex-lover, Noah Hicks, who broke her heart and left without saying goodbye five years earlier. Meanwhile, Sydney tells Sloane that she wants to find her mother; Jack is ordered to see CIA psychiatrist Dr. Barnett to help him deal with his churning emotions after discovering that his wife may still be alive; and Will and Francie become suspicious of Sydney's activities after finding one of her airline ticket stubs.
When Reyes uses numerology to connect the murders of several women to an obsessed serial killer, she and Scully become trapped with a mysterious checker-playing man who may or may not be the killer.
Leela endeavors to become the first female blernsball player, but her lack of depth perception hinders her skills. Nevertheless, she becomes the pitcher for the New New York Mets, purely for her novelty value.
Homer is prescribed medicinal marijuana after getting pecked in the eyes by a murder of crows. While his family and friends worry about the drug altering his personality, Homer becomes Mr. Burns's vice president after cracking up at Burns's antiquated jokes.
Mitzi Huntley arrives back in Nate and David's lives thanks to a comparison-shopping widow. Meanwhile, Ruth's estranged sister Sarah arrives for an unexpected visit. Later, a vodka-fueled family dinner casts a pall over Nate and Brenda's happy news.
Dewey rules, thanks to his new dog that intimidates Malcolm and Reese; Hal and Lois hit the town with big plans---and flu symptoms.
A renegade Amazon, Aresia, leads a new incarnation of the Injustice Gang to accumulate the components for a bio-weapon.
Michael has trouble dealing with the news that his new boyfriend Ben once slept with his best friend Brian. Debbie needs to do something about the dead boy found behind her diner. She impresses Detective Horvath with her sleuthing. Ted gets a shot at being accepted by the elite A-Gays of Pittsburgh.
Ginger really wants her mom to start dating, but when she starts seeing Buzz the handyman (from the episode TGIF) and his three boys invade the Foutley house, Ginger mifht have second thoughts about it.
An arson case inflames Jimmy when he has to defend a respected Italian-American businessman who is an old friend. But his suspicious furniture-store fire killed a night watchman. Jimmy is reunited with the savvy hooker who previously duped him.
Jolyon makes a decision that will break apart the close-knit Forsyte family and change his life forever. Winifred married Dartie against her brother and father's wishes, but they are determined to protect the family all the same. Soames is made happy when Irene accepts his proposal of marriage, but she had conditions because she knows she does not love him. June is all grown up and in love with a promising young architect, Phil Bosinney who she is determined to marry.
A Bang Baby named Madelyn Spaulding turns everyone in Dakota into a zombie. Everyone but Virgil, that is.
A girl who is obsesed with Lori switches bodies with her. Tommy and Merton don't believe Lori in Alices's body but become suspicious at Alice in Lori's body, because she doesn't know what 'wolf out' means. They become even more suspicious when 'Lori' cries. Their suspicions are confirmed when 'Alice' knows Tommy's sercret and 'Lori' doesn't. A subplot is Merton has his own tv show in which a guest star is an rival of his. 'Alice' 'Lori' and Tommy(wolfed out) crash it. Merton averts the camera. The strange creature that Mertons rival Fong (remember him?) brought gets removed from its own body by Alice, in Lori's body. Metron tells them that the three of them have to hold each others hands to undo what Alice did. With the help of Fong they get the three to hold hands. Lori pulls the creature from her body and the creature(what was it called?) pulls Alice from it's body and Alice disappears.
Jack comes upon ruins of a village and realizes it is his home. He then reflects on the past when he was a young boy.
A rebellious 16-year-old teenager is raped and murdered; the case becomes complex when they learn that her stepfather is a judge with whom she has had major problems.
After a near-fatal incident with Logan, Max decides to end their relationship for good. A murder committed by Alec's Manticore twin, Ben, puts him under suspicion and places all of the transgenics in jeopardy...thanks to White and his leakage to the media. Meanwhile, Joshua finds the perfect woman, but can't find the courage to confess his secret.