Father doesn't know best when Quagmire assumes responsibility for a baby left at his doorstep. Meanwhile, Stewie creates a stupid clone of himself that he uses as a slave. When he ends up creating a clone for Brian too, they find out that the clones are unstable, at which point the clones break down.
A woman meets a younger man at a night spot and survives his brutal attack. It triggers a series of investigations and leads to the discovery that a serial killer might be on the loose.
Marge and a group called the "Charity Chicks" pose for a calendar in hopes of raising money for charity, but Marge becomes the talk of the town thanks to her racy poses. Meanwhile, Carl is chosen as the newest supervisor at the nuclear power plant, and hires Homer to be his personal assistant.
The 1991 murder of a 14-year-old girl in foster care who was a promising rapper is investigated. The probe reveals the victim lived in a gang-infested neighbourhood and was recently placed, along with her sister, with new foster parents.
Larry is miffed at both Marty Funkhouser's sudden presence on set during the Seinfeld reunion's table read and text messages from the nine-year-old daughter of a co-worker. Leon poses as a dead doctor to alleviate Michael Richards' concerns over his Groat's Disease diagnosis.
Ojai's newest wine is submitted at a local festival; Justin and Rebecca keep life-changing secrets from themselves; Nora has a crush on a younger man; Sarah and Luc may not be as compatible as they thought they were.
Dethklok join a tribute band to reignite their passion for Rock'n'Roll.
Upset that Francine has let herself go, Stan takes drastic measures when she asks him to renew their wedding vows.
When Tim buys a racehorse from Lisa, he puts everything on the line, including Amy, to win big.
The Guild of Calamitous Intent comes under attack by an insane Phantom Limb, who now goes by the name "Revenge". Meanwhile, Hank and Sergeant Hatred must protect the compound from the Guild's agents. We also learn something very interesting about Dean's birthright.
Fanboy and Chum Chum have a test coming up and if the entire class passes, they win a bouncy house. Fanboy decides to install his brain into Oz's robot to get smarter, but worse results come to follow.
When a heatwave hits Galaxy Hills, the boys see the Frosty Freezy Freeze machine is on the fritz. They try to nurse Berry, the ice monster who runs the machine back to health but wind up getting "Frosty Freezy Freeze Fever" the moment they lick him.
The boys reconstuct one of Doofenshmirtz's inventions to discover what it does after it lands in their front yard.
A story Mickey plans to read aloud about an enchanted egg, suddenly becomes real. The big purple dragon egg Wizard Pete is taking care of, rolls out of the castle and into Donald and Goofy while they are walking to the Clubhouse. A purple baby dragon pops out of the egg. Mickey and friends name it Zoe and take it to Wizard Pete, while trying to get out of his traps.
Phineas and Ferb discover the lost city of Atlantis, Candace enters a sand castle building contest, and Dr. Doofenshmirtz tries to use a growth formula to make plants evil.
Live from New York, it's... Jason Sudeikis! Sketches include "Biden's in Control," "Today," "Rear Window," "WIIX," "A Lady's Guide To Throwing a Party" (film), "Dr. Jekyll & Mr. Hyde," "Toilet Encounters" (Digital Short), and "Cloud Watching." The Black Eyed Peas performed "I Gotta Feeling," "Meet Me Halfway," and "Boom Boom Pow."
Arthur is challenged to a duel by a mysterious warrior. Arthur and Merlin then find themselves on a quest on Morgause's behalf. A dark secret is discovered by Arthur that could change Camelot forever.
Pig has been hanging out with his imaginary friend, Mr. Wiggleplix, for weeks and it drives the other animals crazy. Then one day, Pig claims that Otis killed Mr. Wiggleplix so Otis has to dress up as Mr. Wiggleplix for Pig to feel better. Things take a turn for the worst when Otis says he is leaving for a magical land but Pig believes it and wants to go with him. All of the sudden, the real Mr. Wiggleplix comes alive and stops Otis from impersonating him.