After Chelsea discovers a nude picture of another woman on Charlie's cell phone, he blows off steam by going out for a night of drinking with Alan, Herb and his neighbor.
When Barney learns Ted has a list of things he thinks the gang is too old to do, he sets out to do every task within 24 hours in order to prove Ted wrong.
A man awakens in New York after a bicycle accident unable to move or communicate in any way. House, himself injured in a motorcycle mishap, occupies the hospital bed next to Lee and quickly annoys the doctors treating them both by insisting that Lee has “locked-in” syndrome.
Serena throws Jenny a sixteenth birthday party, but things spin out of control when Poppy Lifton turns the party into the social event of the season. Vanessa agrees to help Chuck in a plan concerning Blair and Nate. Meanwhile, Rufus searches for a way to cover Dan's tuition when he learns he will not receive financial aid to go to Yale.
While Julian makes Brooke a surprising offer, Lucas takes Nathan and Jamie to an important place from his past. Meanwhile, Peyton prepares for the future; Sam and Jack go up against the principal who fired Haley; and Skills and Mouth go on a road trip to help Mouth forget Millie.
Wolfe faces a terrible dilemma when he's forced by an unknown assailant to cover up evidence in a murder/robbery, or else the kidnapped Billy Gantry will be killed....
A female agent is sent to evaluate Sarah's performance, when Chuck's feelings for her are revealed. Meanwhile, Morgan, Jeff and Lester are trying to get invited to Captain Awesome's bachelor party.
Penny squares off with a new beautiful female neighbor who may become the building's "new Penny."
The investigation behind a body found wrapped in a rug on the sidewalk leads Castle and Beckett deep inside the world of New York City politics. The partners discover a world of expensive escorts, arrogant tycoons, corrupt investigators, and the effects of betrayal.
Grace takes on an investigation when a jogger with a intricate love life is found dead. Meanwhile, Clay's father and a new bartender from a local joint begin dating, and Grace worried that this will have a negative impact on Clay. Leon gets a visit from a former high school classmate.
Now that Nathan’s ability has been revealed and he has lost control of his operation, he and Claire go into hiding in Mexico. With Emile Danko now in control of the government operation, his plan to destroy everyone with abilities is set into motion as he teams up with an unlikely partner. Meanwhile, Angela and Peter seek refuge in a church and begin to mend their broken relationship.
Charlie is saved from Helix's hybrids, leaving Stan behind. Will Charlie disobey direct orders from Hall to go back and save him?
Was the arson attack on a Turkish club claiming 17 lives racially motivated - or something even more sinister? James Steel and Alesha Phllips struggle to build the case.
When Emma inadvertently finds herself a substitute teacher at the elementary school she asks Karen and Wanda to talk to the kids about their careers, causing tension to erupt. Lacey's attempt to make the Ruby more birthday friendly goes too far. Meanwhile, Brent and Hank panic after they suspect Oscar has eaten a thirty-year-old snack cake.
Eli starts to get envious of Maggie going out with Paul, especially since Paul works at Posner & Klein, where Maggie works. Meanwhile, Eli fights for the little man against a greedy CEO whose bad decisions cost hundreds of jobs.
A woman struggles to find a balance between her dissociative identity disorder and raising a dysfunctional family.
Queen Rose prepares for First Night. She expects Silas to be here for the entire event but Seth, his illegitimate son, has become very ill. Helen begs him to come to his side. Jack invites David to a night on the town with his friends from the army. Michelle on learning that David followed Jack instead of being at the Ballet decides to chat up with a very old friend, Paul Ash.
Everyone's trying to bluff, and Daniel Negreanu can't catch a hand as Doyle Brunson, Peter Eastgate, Barry Greenstein, Tom Dwan, David Benyamine, Ilari Sahamies, and Eli Elezra join "Kid Poker" for High Stakes Poker.
The celebrities challenge is to take over a ritzy hotel, which will include answer to the guests every beck and call, clean the rooms, manage concierge affairs and delivery room services. But this task does not bold well for an out-of-control manager and unhappy guests.