The burden of leading weighs heavily upon Clarke and Bellamy when different challenges force them to determine who will live and die.
In a local Chicago diner, Michael brings new meaning to the term hold the pickles. Plus, he discovers an aggressive new breed of fungus at a park, and later, he helps a co-worker disappear from work early in a hospital warehouse.
The doctors work with the Center for Disease Control and Prevention to find an antidote to the deadly viral outbreak at Angels Memorial. Also, Leanne makes a life-changing decision, and Jesse welcomes a new batch of residents.
Sarah and Cal learn that the FBI is investigating The Movement. Hawk and Noa grow closer, while Mary and Sean deal with challenges to their relationship. After an outburst at the casino with Chloe, Eddie joins a support group for former cult members.
Star must show her fairy godmother, Baby, what she has learned about magic.
The guys throw their own version of Coachella to impress a group of festival girls.
A brutal car crash reveals that Cahill is the target of a murderous stalker, causing Riggs and Murtaugh to turn the tables and start asking her questions for a change. After finding Murtaugh's file in Cahill's office, Riggs becomes obsessed with finding out about his. Roger and Trish reel over their daughter's newfound fake ID.
Sky ends up with stitches when Tiffany confronts her about her attitude. Melody wants to return to Black Ink. Sky shares a closely guarded secret with Ceaser. Richard and Nikki's wedding celebration turns ugly
Mary confronts Ben. Grady blackmails Mary into helping him break a patient out of the hospital. Ben and Frank get a new lead.
The body of a 15-year-old girl is found crushed in an abandoned building after she runs away from a treatment center for troubled girls. Voight sends Halstead undercover as a guard to work from the inside at the center, where he believes the girls are trading sexual favors for something in return.
Despite personal financial hardship, Nelson takes on the grueling task of raising funds for the ANC. Once he ends up at Robben Island serving a life sentence, his friend Oliver keeps the struggle alive on the outside.
With Deering suspended from duty, she runs rogue determined to get Nora. Back at the station, Lickberg tries to control the team, as they urgently up the manhunt for one of the Attahs' missing victims. And an unlikely alliance is agreed between Deering and Nora, who wants to stop an FGM cutter arriving on her patch - and Teegan is sent in under cover.
At 661 lbs, Erica regrets not keeping a promise to her mom. She hopes her siblings will help but they are reluctant based on past failures. Each meal threatens Erica's worst fear coming true; dying the same way she lives, alone & surrounded by food.
With Pieter holding Ava hostage, Jake and Freddy must come together to save her the investigation into Pieter begins to close in on Green Green Cam strikes out on his own, making a deal with the cartel.
The miners of Nome continue their far flung explorations in search of new gold. Zeke and Emily head to Sledge Island and Shawn continues his dreams of gold at the Bluff. Meanwhile, the Kellys reputation may sink them before the season starts.
The team sets out to free Faber. Aurora takes on a new undercover job.