Gonzales and Coulson must find a way to put their differences aside and work together against HYDRA, even if it means teaming up with someone they don't trust.
Justin steps up when Leslie needs someone to go with her to a work event.
Barry, Caitlin, Cisco and Joe set a trap for Wells. Cisco uses himself as prey which puts him in grave danger. Meanwhile, Eddie makes a decision regarding Iris, which leaves Joe a bit unsettled.
After being slotted for an aggressive confrontation with Ferguson, Liz's world is rocked with the arrival of a new prisoner. Franky has commenced her sessions with Bridget, and in a candid moment admits to a desire for revenge against Bea. When Bea is shivved in the yard, Franky comes under suspicion, but Bea quickly realises Jodie, freshly released from the Slot where she was terrorised by Ferguson, was behind the attack at the Governor's behest.
The school counsellor advises Carter to take her studies more seriously; Taylor learns the truth.
Reese and Fusco get caught in the war between the two newest POIs, rival crime bosses Elias and Dominic. Also, a tantalizing clue to Shaw’s whereabouts leads Finch and Root into a possible trap, and Control goes rogue to uncover the true intentions of the Samaritan program.
With no memory of the night before, Lasalle’s brother, Cade, turns to NCIS for help when he finds his girlfriend’s body in the trunk of his car. Despite a mountain of evidence that implicates Cade, and the case being under Captain Jim Messier and Jefferson Parish jurisdiction, Lasalle is determined to prove his brother’s innocence.
Lt. Suzuki dedicates all of the police resources to finding the killer of a rich white girl who died of exposure after an eight-month disappearance. The girl gives birth before she dies, and Liv soon starts having maternal feelings toward the baby and everyone else around her. Meanwhile, Major tries to find out more about Julien, and Liv and Lowell's relationship changes when he eats the wrong brain.
A fire threatens the Cornelia Marie. Keith has a showdown with his crew on the Wizard. Sig receives a shocking surprise aboard the Northwestern.
An apartment fire connected to a case of rape and attempted murder resembles an unsolved case in New York, so Sgt. Benson of Special Victims Unit comes to Chicago to help Intelligence with the investigation. The crossover continues on Chicago P.D. S02E20 The Number of Rats (II) and Law & Order: Special Victims Unit S16E20 Daydream Believer (III).
A challenge involving exotic proteins, including alligator, ostrich and wild boar, is followed by chef Ramsay giving the remaining nine contestants one-on-one evaluations and sending one of the weakest team members home.
Abe tries to recruit a new agent; Caleb and Rogers race to hunt down intelligence from London; Andre's history is exposed.
As Castle and Alexis travel to London, their routine flight turns deadly when the plane’s Air Marshal is found murdered. With the help of Beckett on the ground, Castle and Alexis race against time to find the killer before he carries out his fateful plan.
Romero confronts Norma about new information that has recently come to light. Norman reels from a recent discovery. Caleb and Dylan take a job that involves some risk. Emma makes a decision about her future with Norman.
With Joe Carroll's execution day upon them, the team remains on edge, expecting that he won't go easily. Their fears are realized when a hostage situation at the prison forces Ryan to go in alone, as the whole world watches.
Larry becomes an acting part-time villain as he substitutes for the ailing Rippen. The team's mission is endangered when Penn takes pity on Larry.
Elijah and Freya think differently about how to deal with Dahlia's deadline.
Beth desperately fights for her life after her deranged stalker drags her to a remote cabin in Ojai, leaving Jack and Janice to frantically search for clues to their location. Also, the TAU waits for updates on Ben’s prognosis after he was shot.