Bert Large abandons his plumbing business in favour of running a restaurant. Following the restaurant's opening, several cases of food poisoning occur with Louisa being one of the people affected.
An Internet celebrity's boyfriend is killed with a bow and arrow. During the case, Horatio becomes a "cyberlebrity" himself, which puts his life in danger.
When Joan buys an expensive new kitchen range for their new house, her fiance Aaron get upset that she spent money without discussing it with him. Later, after Joan and Aaron stop arguing, he receives news that his National Guard unit is being called to Iraq. Meanwhile, Lynn is enjoying her newfound success with her music career and begins to flaunt it.
Hank receives bad news about his father and embarks on a grief-stricken bender of booze, drugs and even a prostitute as he remembers the last time they saw each other.
A philandering billionaire playboy who moonlights as the superhero, Awesome X, faces against his greatest adversary, Killface, but finds balancing his business and superhero lives difficult.
With Audrey's sister, Barbara, having problems in her marriage, the only thing she doesn't need is a man who would trick her to try and get her to sleep with him. But, sadly, in Audrey's life there is a man just like this. During this episode, Russell will try everything to get a one night stand with Audrey's sister.
An unscripted program that pairs MENSA-worthy "geeks" with gorgeous women.
The gang celebrates Brody's birthday in Vegas. Audrina's boyfriend Justin causes a rift in her friendship with Lauren.
Charlie acts strange after spending an evening with his mother, and a woman Alan slept with behaves oddly the next morning.
Five teenagers must locate and secure ancient relics with unbelievable power, while at the same time stop a demonic corporation who want the relics for their power.
A law school graduate becomes the protégée of a successful high-stakes litigator.
Peter falls in with Irish gangsters who know about his past. Hiro works to contain the damage caused by his journey into the past. Kensei's power will be revealed. Suresh locates and cures the Haitian. Matt investigates the murder of Mr. Nakamura. West comes to know of Claire's powers. Maya and Alejandro enter Mexico and find their powers more of a hindrance than a help.
Whistler tells the truth to Michael. Michael tries to get in touch with Sara but the only phone is in Lechero's quarters, so he has to rely on T-Bag's help. Mahone battles his addiction. Bellick steps on some toes.
Ted and Barney pretend to be visitors to New York City to pick up women. Robin is still dating Gael.
Falafel's Drive-In (San Jose, CA), Ramona Cafe (Ramona, CA), Silk City Diner (Philadelphia, PA) Guy stops into a Philly diner for some fried spring rolls, a diner in Cali for deep-fried falafel, and a small town diner for fried chicken cordon bleu.
Celia and Sullivan step up their relationship. Andy gets more involved in a different business. Silas and Tara begin working together. Shane and Isabelle spend time together. Nancy meets Peter's other ex-wife, Valerie.
As Chuck is beginning to adapt to his new life as a spy, a doctor who could possibly "cure" Chuck is murdered. Chuck then begins a high-speed fight for his life, all while trying to decide which of his two new colleagues might be out to get him. Meanwhile, Chuck's sister Ellie invites Sarah to dinner to meet the family.
Leonard volunteers to sign for a package in an attempt to make a good impression on Penny, but when he enlists Sheldon for help, his attempt at chivalry goes terribly awry.
When Chris does poorly on an exam, Ms. Morello sends him to the school's guidance counselor, Mr. Abbott. The counselor gives Chris a series of mental evaluations and ultimately determines that he must take a remedial course.
Now You Know is the fourth season premiere episode of the American comedy-drama series Desperate Housewives, and the st episode overall. The episode premiered on ABC on September , . It was written by series creator Marc Cherry and directed by Larry Shaw. In the episode, Susan learns that she is expecting a child while Bree continues to fake her own pregnancy. Gabrielle begins an affair with her ex-husband, Carlos and Lynette tries to conceal her cancer from her friends and children. The episode also introduces Katherine Mayfair, Susan's old friend who returns to the neighborhood after being away for years. Now You Know drew over million viewers, becoming the fourth most watched program of the week across all networks. Nevertheless, it was the least watched Desperate Housewives season premiere at the time. The episode received positive reviews from critics, who agreed that the episode showed significant improvement over the show's third season. Critics also praised the addition of Delany to the cast. ABC and the show's producers received viewer backlash due to an alleged slur against Filipino doctors included in the episode.