A new villain named Scorpio shows up in superhero city. Nicky Fury disguises himself as a villain to infiltrate Doom's Headquarters to stop Dr. Doom from using a fractal to control a black hole.
A man wants an investment from the sharks to create an extension of his already successful business; a urologist has an unusual business proposal.
The Major Crime and NSO investigation into the car bomb deaths results in Malik going undercover to track a possible suspect. While he is undercover a Chinese student is discovered murdered. Detectives Lim and Callas get to the bottom of an extortion ring.
Doug and Ellie rented for over two decades. Then, when they were able to buy a home, they made a quick decision. With two children almost ready to move out, the house doesn't fit the family or the future. Designer Hilary and Realtor David are ready to help. Hilary and her team will revamp the house to fit the family's needs. David will search for homes to fit now and later. In the end, Doug and Ellie will have to choose what to do with their house. Will they Love It? Or List It?
Eric Matheson (Garret Dillahunt) is determined to prove that he didn't murder his wife. Torres is assigned to investigate the murder, and goes to the house of the victim's sister. Matheson finds Torre's car and gets into it after she forgot to lock the door. When Torres returns, Matheson holds her at gunpoint, instructing her to drive to the Lightman Group offices. Cal makes a deal with Mattheson, asking him to let all the employees go as long as he helps prove Mattheson's innocence. Mattheson complies, and Foster, Loker, Reynolds and Torres attempt to solve the case, while Loker has second thoughts about not calling the authorities. Cal and the team find out that Mattheson was actually innocent, and that his wife was actually killed by a creditor. Mattheson demands that he sees the creditor, saying he will either take his life or Cal's. Cal pleads for Mattheson to kill him, but Foster, Loker and Reynolds trick Mattheson into letting his guard down after a disguised Loker pretends to recount the last moments of Mattheson's wife's life. As Mattheson is in a moment of rage before killing Loker, Reynolds draws his gun and shoots Mattheson, disarming him. The episode ends with Lightman at Foster's home, asking if he could sleep in her spare room for the night.
Under Samuel’s guidance, Sylar starts on a path to rediscover his true identity. Hiro helps Emma accept and understand the great possibilities that go along with having an ability. Meanwhile, Peter enlists HRG to help him find a healer who can save Hiro’s life.
After overhearing that Wil Wheaton is entering a trading-card competition, Sheldon decides to enter it himself. Meanwhile, Penny sets up one of her friends on a date with Wolowitz.
Vanessa, hoping to finally win her mother Gabriela’s approval, desperately vies with Blair for the honor of delivering the freshman toast at NYU, but at what price? Dan invites Olivia to meet Rufus and Lily, which leads to all sorts of problems for the new couple. Serena and Nate team up to help Carter Baizen.
Barney tries his best hoping to convince Robin into becoming an American citizen, while Ted and Marshall's road trip takes an unexpected turn for the worst when Marshall invites Lily to come along.
Cattlemen's Steak House (Oklahoma City, OK), Sam LaGrassa's (Boston, MA), Nickel Diner (Los Angeles, CA) Guy Fieri checks out some joints where things are still done the old-fashioned way. In Oklahoma City, a steak house that's been serving the same steaks, desserts and even salad dressing for more than 80 years; In Los Angeles, a 1940s diner brought back to life by a chef doing mac and cheese, fried catfish, and donuts ... her way; And in Boston, three brothers carry on 40-year-old family tradition - making clam chowder like Dad - and chipotle/pastrami sandwiches.
Castle has a new book agent, Paula Haas, but she talks with him when he has gotten an opportunity that may change his career. The downside is that taking the opportunity would mean the end of his relationship with Beckett. Meanwhile, an unidentified woman is found dead in a manhole.
Haley considers taking matters into her own hands as Nathan’s scandal threatens his endorsement deals. Julian gives Alex another chance, and Brooke reconnects with Chase. Millicent questions whether she has what it takes to be a model. Meanwhile, Clay lets Quinn in on a big secret.
A dying patient insists that he has the same disease affecting his heart that killed his father and grandfather at the age of 40. Meanwhile, House discovers that he has a hearing problem while trying to duck student rounds.
Jake stops at nothing to get away from Charlie and Alan, after they embarrass him out in public.
Lucy’s dream comes true when Natsu and Happy take her to their headquarters in Magnolia to meet the rowdy members of Fairy Tail. For her first job, Lucy braves Mt. Hakobe with her new friends to find a missing wizard.
Alexx Woods and Eric Delko return to help the CSIs stop a deadly outbreak in Miami.
Lizzie makes her peace with Johnnie's death, and Sage's invitation to go out on the town with Cassie may do more than take her mind off of Charles.
In Casey and Ashleigh’s continuing struggle to bring ZBZ back to the top, Ashleigh decides a four-way mixer is the best way to gain their popularity back. Will her party save ZBZ from the fourth spot, or will she put them in even more debt?
After returning from France, Sarah manages to distract Kitty through her chemo treatments by using tales of her romance with a French artist. Meanwhile, Justin has problems with his anatomy class and seeks his professor for help with surviving the semester with his teenage genius lab partner.