Liz Lemon, head writer of the sketch-comedy show "TGS with Tracy Jordan", must deal with an arrogant new boss and a crazy new star while trying to run a successful television show without losing her mind.
Angie continues to let George believe she's pregnant after finding out she's not, just to ease the pain of Carmen going away to school, while Vic introduces his hot new girlfriend to the family.
Veronica is hired to track down a one-night-stand, but the situation becomes more complicated when she turns out to be a hooker. Meanwhile, Keith continues his investigation in Dean O'Dell's death, and a visit by Madison Sinclair causes trouble for Veronica and Logan.
Mike joins the Bowie BaySox team at Prince Georges Stadium in Maryland acting as a groundskeeper. Next he fixes boat moorings with a former Navy SEAL. He then joins Watson Water company dig deep through mud, rock, gravel, sand and water as they drill for heating and water in Tennessee. Also, Mike takes a dive into the mail bag.
Rory makes amends with Lucy while Christopher finds the letter Lorelai wrote for Luke's character reference. Rory witnesses a frightening sight while at Richard's Economics class. Sookie is acting weirdly so Lorelai makes Jackson confess: Sookie is pregnant again, even though Sookie told Jackson to get a vasectomy.
While House is forced to work full-time in the clinic and deal with a rape victim who insists on confiding with him, Cameron deals with a terminal cancer patient trying to take advantage of her state of mind.
This episode demonstrates the production processes for pistons, paint rollers, parachutes and chimneys, and shows how each is made.
Denny takes Bella's case against an animal rights group opposed to her cosmetic testing procedures, and her daughter Bethany is opposing counsel. And at the same time, Denny wants to dump Bella because he's still in love with Bethany.
Maya fears Jabari is growing up too fast when she sees him interact with a young girl. Joan is uncomfortable using the bathroom at Aaron's house.
The Sutton household is threatened when Jenn's sister is targeted by a stalker.
A televised poker cash game in which top pros including Sam Farha, Doyle Brunson, and Johnny Chan compete. This is not a tournament however, each player is playing with their own money and they have the option to buy in again.
Jo helps out Suzanne and Shane Haines, whose 4-year-old son, Sean is ruling the house: crying, hitting, swearing, kicking, and biting his parents along with his big 10-year-old brother, Seth, who is resentful because of Sean's behavior, so he talks back and antagonizes his parents in order to get their attention. The parents are passive and allow the boys to get out of control. Can Jo help get the Haines family more lively?
When an uninvited Audrina shows up at Heidi's birthday, she learns Heidi's not ready to forgive and forget. Lauren, determined to focus on work, falls for the charms of the new guy in her life, Brody.
Jack finds himself confronting his father while the lead terrorist needs help if he's to explode the remaining bombs.
In Mexico, Sucre gets a car but gets in trouble by the police. Bellick has more trouble as the new inmate as prisoners who suffered with him want revenge.
Hiro continues to search for a sword while being chased by mysterious figures. An invisible man named Claude has something to teach one of the heroes. D.L. takes on new family responsibilities, and Matt opens up to his wife. H.R.G. continues to focus on the captive Sylar. Claire seeks out the Haitian and then her birth parents. Mohinder looks for those on the list, and receives a surprise visitor. A psychiatrist offers to help Niki.
Chris gets no respect when he has hall monitor duty. Greg tells him to step up his game but the power goes to Chris' head and he could lose Greg as his friend. Tonya finds out her popularity is because the girls want to get close to Drew.
Hopper unexpectedly meets again with Jared - the guy who bit him in the fifth episode - and finds out that he is not the only one reliving the day over and over again. He also finds out that there was an eye-witness and that he was identified as Garza's murderer, while realizing that he has to deal with very powerful people. He also learns that people that are close to him might know more than they say they do.