When burglars break into the house, the Griffins take cover in the attic, where Peter tells them about their family history.
Reaching the end of her rope, Bree checks herself into the Fairview psychiatric hospital. Lynette suspects that Tom is cheating on her, so she follows him to Atlantic City. Susan must start over. Felicia Tilman has more in store for Paul Young, resulting in their war reaching its final battle. Gaby and Carlos get Xiao-Mei pregnant.
Working through their checklists of things to do before summer ends, Lisa gets the family to go a museum. At the Springfield Museum of Natural History there is an exhibit Lisa is excited to see on Women’s History turns into an exhibit on the history of weapons, which excites Homer and Bart. When Flanders sees the exhibit of evolution and another that mocks creationism, he raises an alarm. Reverend Lovejoy gets Skinner to have creationism taught in school. Lisa is the only one who holds onto the scientific theory. She brings the topic up at the town meeting and the town votes to teach only one theory, creationism. Lisa decides to hold her own class on evolution, until she is arrested. The ACLU gives her a lawyer who is up against a slick Southern lawyer, but ultimately it’s a family member that is a key to her defense.
George and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to keep the baby alive. This causes tension between Derek and Addison. One doctor's overreaction unites two bickering patients. Finn is still treating Doc for medical problems.
Malcolm struggles with his speech when he's elected valedictorian of his graduating class at school. However, Lois refuses to listen to any of his complaints and reveals that she wants him to become President of the United States. Meanwhile, Reese does everything he can to get a permanent job as a high school janitor, which includes creating the most disgusting mess ever. In the meantime, Hal has problems with Malcolm's Harvard tuition, while Francis finally gets a real - job that he actually enjoys. Also returning for the family celebrations is Grandma Ida, as they all say goodbye to Malcolm when he leaves for college.
There is a series of suicides in Arkansas that Norbac is called to investigate. David tries to decipher the work of a friend who died in a car accident.
Tony reflects on how growing up with Janice colors his attitudes now, while Vito tries to make a new life for himself in New Hampshire.
Santos and his staff prepare for the inauguration as Bartlet and his team look back on their years in the White House.
Everyone in the park becomes uneasy about Randy. Randy stays true to his eviction policy - he now evicts J-Roc. Lahey finds illuminating evidence from old footage of the day he lost his badge - he seeks for reinstatement.
In the season finale, after a suburban couple is found bludgeoned to death, Detectives Logan and Barek suspect that their drug-troubled son Kevin killed his parents' for their cash stash. But when a local investigator pressures the kid into a confession, the city cops discover a conflict of interest. While another suspect with close business ties to the victims emerges, Captain Deakins urges Logan and Barek to drop the non-jurisdictional case -- and ponders his own future with the NYPD.
When a church worker is found dead after the latest in a series of arson-fueled fires, Detectives Goren and Eames trace evidence back to the dysfunctional family of one sanctuary's youth leader, Justin Reid. Just as pressing is the personal matter weighing on Captain Deakins, whose intervention on behalf of one detective prompts a vengeful cop already in prison to launch a vendetta to oust him.
A sportscaster must take on the responsibility of being a full-time dad when his teenage daughter moves in with him.
Forced to hide from Billie and Christy, the Charmed Ones find themselves stuck in the Underworld. Meanwhile, Leo appears to Piper and offers demonic approval Coop searches for Phoebe Billie Christy resort to summoning the Hollow to stop the Charmed Ones and the Charmed Ones do the same.
A parody of past religious-geared animated shows starring Orel, an optimistic God-fearing young boy in a world of cynicism.
Huff and Beth have an argument at their therapist's, leading Huff to undergo an experimental therapy procedure. A friend of Beth's comes to town, Byrd and Izzy have a conversation, and Russell does some good.
The escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, while keeping America safe.
A Utah polygamist who owns home improvement stores in the Salt Lake City area juggles relationships with three wives while trying to keep his complex family life from becoming a public scandal.
In Part Two, Zadavia tells Ace and the team that she and her brother Optimatus are from another world and have different ideas about ruling it. She was banished by her brother and found a new home in Acmetropolis.
Omi uses time travel to stop Hannibal before he can turn Chase to evil.But in doing so, he changes the course of history and turns the world upside down.When he returns to his time, Chase is on the side of good, but Master Monk Guan is now on the side of evil, accompanied by Hannibal and Wuya.The Xiaolin monks have lost their Temple and have been forced to hide in the woods.