Michael races against time and his ailing health to break into the Company headquarters to steal Scylla, but the break-in’s success lies with Sucre. Gretchen dresses up for a meeting with the General and one final attempt to get the last card key. T-Bag must make a decision to leave his criminal ways for good.
A baby is taken from her mother's arms in broad daylight, and the team must race against time to find her.
It's Thanksgiving time and Blair is offended when her Mom's new man hijacks her Thanksgiving traditions. Lily attempts to strengthen the frail bond between Rufus and Jenny. Eric discovers a secret about Bart. Vanessa and Chuck help Nate deal with his father.
Daisy protects Clarabelle's secret recipe for oatmeal raisin cookies from Pete.
A birthday party for one of Lily's co-workers leads to Robin connecting with a group of single partiers known as the "Woo Girls". Ted presents a plan for Goliath National Bank's new HQ.
Sarah finds that the strange dreams she's been having while she sleeps are slowly beginning to creep into her waking life, but she has no idea what the dreams mean for her and John. Derek and Jesse investigate a possible Skynet conspirator.
Lucas falls asleep and dreams of a 1940s Tree Hill were he owns Karen's Cafe. Here, Dan is a dangerous mobster and everyone is entangled in his web: Brooke owes him money, Mouth is searching for proof that would link him to Keith's murder, Haley is his former lounge singer, and Lucas is in love with his step-daughter Peyton.
Hank tries to get the truth about Ashby; Karen confronts the record producer; Marcy detoxes at her mother's house; Charlie succumbs to temptation.
Susan's daughter Julie comes to visit with her surprising new boyfriend. Gabrielle learns that Mrs. Hildebrand has made her and Carlos heirs of her entire fortune. A reporter looks to expose Bree's imperfections. Lynette learns Porter and Anne Schilling plan to leave Fairview and disappear. Finally, everyone has gathered at a club to see the guys play in the annual "Battle of the Bands" when a fire erupts, threatening the lives of those in attendance. Some will fall as a hero will rise.
The team keeps trying to rescue Betsy Blane from Syrian captors; Mack has an opportunity to get revenge on Ryan for his affair with Tiffy.
Dexter undertakes to teach Miguel the Code, but doesn't realize he's whetting his partner's thirst for blood. Meanwhile, Debra is one step closer to finding the Skinner but a secret revealed about Anton sends him packing.
Lisa learns she is good at crossword puzzles and enters a city-wide contest. Homer discovers he has a flair for letting loved ones down so he opens Sweet Conclusions Break-Up Service, but lands himself in trouble with his daughter when he places a bet against her in the competition.
As we descend beneath our modern day cities, we are met with ancient and hidden secrets. Journey with us back through history and rediscover cities of the underworld.
Sookie and Sam investigate her most recent vision; Jason helps clean up Amy's mess; Tara becomes angry with Lettie Mae; Lafayette visits a senator.
Kevin overcompensates for his recent pay cut by snatching Nora’s dream house out from under her as a gift to Scotty. Meanwhile Justin cooks up a plan to set Saul up with an unlikely candidate for a date.
Peter's boss Angela sends him back to the third grade so that he can qualify for a work promotion. Meanwhile, Brian, Frank Sinatra Jr. and Stewie open the coolest club in Quahog.
Sav and Anya plan to celebrate their six-month anniversary on the school's overnight trip. Sav's sister Alli tags along, and he becomes furious when he hears the rumors about what she did on the trip. Over at Smithdale, Manny and Emma both have a crush on their roommate, Kelly.
Peggy, Minh and Dale play the stock market together, however they lose money in their initial investment. To improve their odds they decide to study the consumer habits of an "average man" and Bill becomes the subject of their study. Meanwhile, after Peggy buys the family a new flat screen TV, Hank and Bobby have difficulty figuring out all the advanced features.