A parody of reality shows cast with spoofs of several famous types of animated characters.
A female roller derby team member dies during a game. At first glance, it seems that she was trampled to death. However, autopsy reveals that she died from heating up from the inside. The other case involves the death of a writer found in a dumpster and wrapped in an expensive rug.
Van Buren relentlessly pursues a cocky suspect she believes was responsible for driving a friend's daughter to suicide, because he allegedly attacked her with drain cleaner. But her resulting actions could put the case in jeopardy.
Samantha uses her work experience to help both Kitty and Donna liven up their relationships. On Sam's advice, Donna has some bedroom photos taken of herself, intending to send them to Eric, but a series of mishaps puts the photos in a very incriminating place. Kitty takes Sam's advice, and tries some new moves on Red that result in a big change for both of them. Fez has his dreams of what having a roommate will be like, but finds that the reality is quite different.
When a group of four boarding school students discover a supercomputer housed inside an abandoned factory, they find a virtual world called Lyoko and awaken a sentient multi-agent system virus that tries to take over the real world.
Polly Bergen guest stars as Mac's mother, who arrives for Thanksgiving. But first, Mac must deal with a commission's decision to close a Navy base in her hometown, and a friend from law school who wants her to commute his mentally challenged client's death sentence. Meanwhile, Rod hires a slick political operative, who urges Mac to run for reelection. "If you don't start running now," he warns, "you'll be a lame duck for the next two years."
Jim's old college girlfriend Melissa invites him to lunch. Cheryl gives her blessing, insisting that it's an innocent meeting. Jim disagrees, but goes. Melissa says she wants to do business with Jim. At least at first.
This episode demonstrates the production processes for electrical panels, kites, eyeglass frames and toothbrushes, and shows how each is made.
House and Chase find themselves in a serious situation after a young mother with stomach pains dies. Months later, Stacy counsels Chase prior to his disciplinary hearing, and must determine whether Chase made a mistake that ultimately led to the patient's death. She soon realizes he is holding something back.
Bones and Booth investigate a missing woman found in a fridge while Bones reconnects with her former professor.
While on duty, McGee kills a man who is later discovered to be an undercover police officer. When Jenny decides to approve the investigation on McGee, the NCIS team is forced to prove that McGee is not guilty, pushing Gibbs' relationship with Jen to the limit. Meanwhile, Tony is troubled by his past.
When a teenager and her younger sister end up in the hospital after a day at the park, detectives learn that both girls were abducted from New Orleans after Hurricane Katrina along with a third sister who is still missing. Despite the interference of a local reporter, Jackson Zane, detectives are able to catch the kidnapper, a known pedophile, and recover the girl, but when Alvin Dutch dies and the autopsy determines it was Anthrax, Benson puts everything on the line so that she can get the truth out there.
When a drug dealer is gunned down in his home, Horatio and the team must determine who, out of three suspects, committed the crime. Meanwhile, Delko faces a serious threat to his career, and Calleigh makes a decision about hers.
Mona and Dee Dee are half-sisters with the same father who didn't really know each other when they were little and are complete opposites, but as adults they live in the same apartment building and at least try to bond.
Business slows down at the J-Spot, and Joan weighs her financial options, while her silent partner, William, turns the place into a loud, but lucrative sports bar, without consulting her first.
After being forced into knocking back shots, so he will stop thinking, Ted goes on a partying rampage. The next morning he wakes up with a woman in his bed, but he does not know who it is. So he turns to his friends to try and piece the night together and work out who the woman is in his bed.
Allison dreams about hitting a girl with her car and a woman who's house is haunted. She finds out that the woman killed herself. Now Allison is trying to put all the pieces together.
Lydia becomes jealous when the kids befriend Crystal, then makes them go with her to visit their former housekeeper.
With Lincoln's execution scheduled for the following day, Veronica comes out of hiding to contact him and gains an ally. Kellerman makes the ultimate sacrifice to preserve the conspiracy. Michael looks for a way to get Lincoln out of solitary confinement in time for the escape that evening. The inmates risk everything as they attempt their escape.