Nancy's up and running again until someone betrays her and sends in the DEA. Celia spends more time with Dean. Doug has ethics decisions to make.
A new threesome including Hank and Charlie evolves from a meeting at the gym, while Karen and Marcy have a girl's night out at which they decide to surprise Hank and Charlie.
Audrey gets a lesson about the 'guy code' when Jeff shares a secret about a new friend.
Wretched with amnesia after an accident, Samantha attempts to discover her life again. After being the victim of a hit and run, Sam awakens to the shock of everyone that she doesn't remember any of them, not even her parents who were standing over her bedside.
Rebecca worries about Justin, Tommy's marriage hits a road block as Julia starts coming out of her depression. Kevin meets an old flame and Kitty prevents a scandal.
Arlen is hit by a heat wave and Hank and the gang take the kids to the water park. Unfortunately, when they have to tangle with a group of surfer bullies, Boomhauer, who is usually cool, winds up embarrassing himself. Meanwhile, Bill becomes known as the famous "Heat-Waver" when he begins to stand on the side of the highway and wave to motorists.
Sharon's always been unlucky in love, until now that is, Kath and Kim go into planning mode for the event of the century! Brett gets the job of a lifetime and finds a perfect new place to live with Kim and Epps. With the house to themselves Kath and Kel embark on a new business venture and being people's, people there is no way they cannot fail. Looks like it's all going to end happily for everyone...Or is it?
While Killface prepares for the Presidential debate, Xander makes a few stops with Ronnie before he arrives at the debate. Both Xander and Killface come to realize that neither of them are qualified or allowed to run for the Presidency due to discrepancies they've both overlooked. Killface decides to follow up on his original plan to destroy the world.
Jessica finds herself in trouble when her friend, Medical Examiner Laura Fields, is caught tampering with evidence in their murder case. When confronted in court, she accuses Jessica of having pressured her for a false testimony and to arrange the evidences to gain a conviction, when Jessica was the D.A.
Stan prays for a friend and one is provided: a guy named Brett who's like him in every way but one--he's an atheist. So Stan has some evangelizing to do. Meanwhile, Steve is accepted into wizardry school.
Amy and Lou Fleming, and their grandfather Jack, deal with life after their mother's death while a new ranch hand, Ty Borden, comes to live and work at Heartland.
A toaster makes life tough for Loretta and Leon; Larry gets to know an exterminator.
Marge is held hostage during a bank robbery and forms an uneasy bond with one of the thieves before he's taken to prison.
Bree informs the housewives of what she overheard in the Mayfair house. Stella makes some special brownies to help Lynette through chemotherapy. Susan throws a charades party for the whole neighborhood.
Colin helps Michael and Eileen cope with the unexpected death of a friend while Freddie tries to avoid a war with the Italians; Tommy helps smooth things over with the Speaker of the House's mistress.
Dexter sets his sights on a new victim: a murderer so repulsive it seems only fitting that he's a used-car salesman. Dexter's been unable to lie to Rita about his midnight activities, which has her thinking that he's a drug addict. She's threatened to leave him if he doesn't commit to a 12-step program to deal with his supposed addiction. While in this recovery, though, Dexter meets a sexy, mysterious woman named Lila.
Nikki and Jonesy spend some quality time at Jonesy's house, until Nikki needs to use the bathroom next door to Jonesy's bedroom, and a faulty flusher causes a flood. Meanwhile, Jude starts secretly dating a senior named Melinda Wilson. (Rachel Wilson guest stars as Melinda Wilson.)