Detectives are troubled to learn that someone has taken an online game too far when a girl goes missing.
House is secretly trying to treat a fighter pilot who is a candidate for NASA's astronaut training program. Her diagnosis will be the test to choose which ones of the 40 applicants are going to take the empty spots in his team.
Missteps. Missed cues. Relationships pulling together. Relationships tearing apart. That's Lincoln Heights, as Eddie tries to bring an end to the endless gang warfare by getting everyone - the All Stars and the Shilohs - to play together as a team in the city basketball championship. But trust is missing, and no one can move forward. Which is a problem that seems to be infecting the Heights. Charles doesn't trust Cassie's new friendship with Luc, and he's telling her he wants out for good. Even lovebirds Eddie and Jenn are having problems with each other. Which is nothing compared to Eddie's problems with Lund. When Cassie and Sage get arrested together, Lund's defense of Sage at Cassie's expense has Eddie fighting mad. It's clear everyone needs to cool down, start talking and find a way to trust. But if opportunities keep turning into dead ends, it's anoyone's guess what will happen.
Jonas works out a plan and the team reunites to clear their reputation. Kim is working behind the scenes to keep the CIA away from the other wives.
A new lawyer at the firm draws instant attention from Alan, who is busy helping Jerry and Katie on a murder trial and fielding an offer from Gloria to be the father of her child. Meanwhile, Clarence and Lorraine represent a woman whose affair with her pastor resulted in a loss of her faith.
Peter falls in with Irish gangsters who know about his past. Hiro works to contain the damage caused by his journey into the past. Kensei's power will be revealed. Suresh locates and cures the Haitian. Matt investigates the murder of Mr. Nakamura. West comes to know of Claire's powers. Maya and Alejandro enter Mexico and find their powers more of a hindrance than a help.
Whistler tells the truth to Michael. Michael tries to get in touch with Sara but the only phone is in Lechero's quarters, so he has to rely on T-Bag's help. Mahone battles his addiction. Bellick steps on some toes.
Ted and Barney pretend to be visitors to New York City to pick up women. Robin is still dating Gael.
Falafel's Drive-In (San Jose, Calif.) • Ramona Cafe (Ramona, Calif.) • Silk City Diner (Philadelphia, Pa.) Guy stops into a Philly diner for some fried spring rolls, a diner in Cali for deep-fried falafel, and a small town diner for fried chicken cordon bleu.
Celia and Sullivan step up their relationship. Andy gets more involved in a different business. Silas and Tara begin working together. Shane and Isabelle spend time together. Nancy meets Peter's other ex-wife, Valerie.
As Chuck is beginning to adapt to his new life as a spy, a doctor who could possibly "cure" Chuck is murdered. Chuck then begins a high-speed fight for his life, all while trying to decide which of his two new colleagues might be out to get him. Meanwhile, Chuck's sister Ellie invites Sarah to dinner to meet the family.
Leonard volunteers to sign for a package in an attempt to make a good impression on Penny, but when he enlists Sheldon for help, his attempt at chivalry goes terribly awry.
When Chris does poorly on an exam, Ms. Morello sends him to the school's guidance counselor, Mr. Abbott. The counselor gives Chris a series of mental evaluations and ultimately determines that he must take a remedial course.
Bert Large opens a restaurant in Portwenn, but when a food-poisoning alert appears to be connected to it, it could be a short-lived opening. When Louisa contracts food-poisoning, Martin is rather self-consciously forced to treat her in her bedroom.
Charlie acts strange after spending an evening with his mother, and a woman Alan slept with behaves oddly the next morning.
Hank's father dies. Despite the memories of his father floating to the surface, he doesn't want to go to the funeral. To ease his pain, he goes to bed with a hooker named Trixie, despite the fact he doesn't have enough money to pay her. Meanwhile, Karen does her best to help him overcome the pain.
With Audrey's sister, Barbara, having problems in her marriage, the only thing she doesn't need is a man who would trick her to try and get her to sleep with him. But, sadly, in Audrey's life there is a man just like this. During this episode, Russel will try everything to get a one night stand with Audrey's sister.
Stalkers turn an innocent teenage swimming star into a sex symbol plasting photos of her over the internet. When following her it is discovered Horatio may be in danger after his testimony in a grand jury.
Joan causes a dispute between herself and Aaron after purchasing an expensive kitchen range for their new house and not discussing it over with him. After they defuse their feud, Aaron receives unexpected news. Meanwhile, Lynn begins to flaunt her success with her progressing music career. Golden Brooks, Reggie Hayes, Keesha Sharp and Khalil Kane also star.