The new owner of the Montecito, A.J. Cooper, introduces himself to the staff an brings a new campaign with him: "Anything Can Happen." The staff get worried that people might get fired. Sam is seeing a psychiatrist because of her recent abduction, but she won't open up to him. Instead, she tells him everything about her colleagues.
The Montecito staff members along with the Las Vegas police have their hands full as they try to discover who killed Mary's father while investigating the recent hotel robbery. A mysterious cowboy pays the tax debts of the Montecito and becomes the new owner.
After the events of "The Janus List," Colby escapes from custody. Don and the team go after him, but everything may not be as it seems.
When Guy's daughter Chloe gets appendicitis, Lee and Tim are left looking after her son Dillon while Guy and Lucy visit her. While in their care, Dillon swallows a subbuteo football and Lee and Tim have problems locating it, and try to think of ways to get it out of his body. However, it later turns out Dillon did not swallow it after all. Lucy is worried about the age gap between her and Guy.
Jimmy is invited out to meet Siobhan's father. His nerves aren't helped when Diana decides to tag along. Diana and Siobhan's dad soon hit it off but when Diana wants out of the relationship it is up to Jimmy to help her end things.
An aspiring writer develops an obsession with Wicca, which alienates her Christian son and unleashes powers that she can't control.
When a series of vampire-style murders plague L.A., immortal investigator Mick St. John sets out to find the culprits and re-connects with a woman, Internet reporter Beth Turner, from his past at a crime scene.
Earl begins his prison sentence. Meanwhile, Joy tries to repay Earl by taking care of Randy (who is struggling to adjust) and a prison bully is looking for Earl.
Michael comes to believe the office might be cursed in the wake of a freak accident. After scrutinizing each of his staffers' religious beliefs, he organizes a charity 5K "fun run."
During Clark's battle with the last Phantom Zone wraith, Lex is rescued by a mysterious woman. She then goes to the Kent farm and reveals she is Clark's cousin, Kara, from Krypton.
Red wants to play with Little Boy Blue, but he keeps running away. The Super Readers travel into the Little Miss Muffet book and have discussions about the book.
Don loses an account. Roger, stuck in the city for Labor Day weekend, attempts to cheer him up. Meanwhile, Joan has a night out on the town with her roommate.
Floating in deep space with the city's protective shield failing, the team must do all they can to keep Atlantis alive. A radical injury threatens Dr. Weir's life.
Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Another two new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her.
Meet Belle, a high-priced high-class prostitute who describes her life and her adventures. She meets with her clients and runs into some problems when she breaks her own rules.
Betty's life is turned into turmoil after the numerous upsetting events that have recently occurred. Despite all this, she refuses to accept the fact that Henry's leaving has deeply affected her. Meanwhile, Amanda has a hard time coping with the news she recently discovered about who her real mother is and Wilhelmina plans to use all the recent tragedies to her advantage.
The four-year-old adopted son of a celebrity couple is kidnapped, and the team must determine if the reason has to deal with the parents' status or the boy's own Sudanese origin.
The CSIs race against the clock to find an injured Sara, who has been kidnapped and put under a car in a remote area of the desert by the Miniature Killer.
Season Premiere. Moretti's first day is challenging as the ER is inundated with casualties from the peace rally - including Neela. Dubenko faces a crisis in surgery. Abby, Pratt and Morris conspire about how to deal with a shared problem. A new intern arrives unexpectedly, and Gates is reassigned.