Bailey returns to prove Krypto's secret identity as Superdog. Only this time, Andrea has to help Kevin keep the secret when he finds out about Supercat.
Boogie Gus invents a gun ray that can not only make people look like from the '80s but also makes them younger! In the b-story, Jerry is having a date with his friend from the band. Villain: Boogie Gus (L.A.M.O.S.).
While the gang starts to learn more about the Prophet 5, Sloane is distressed to learn that Prophet Five's cure for Nadia is just as likely to kill her. Meanwhile, Devlin returns, the search for Anna Espinosa continues, Rambaldi's prophetic Page 47 resurfaces, and Sydney offers Renée a job at APO.
Two women both claim to be the wife of a murder victim surprise Mac and Stella at the circumstances of their relationships. Both women have been in a trinogamous marriage with the victim. Meanwhile, Danny and Lindsay investigate the murder of a young woman who is found off a dock tangled up in kelp while she is dressed as a mermaid.
Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
After undercover cop Dana Baker is murdered, Fontana and Green learn that the man who killed her had discovered her identity after seeing a photograph of her.
Name partner Edwin Poole returns from a mental institution to Crane, Poole and Schmidt, ready to jump back in, but Shirley has reservations when he decides to sue a candy company. An A.D.A. with a grudge against Alan brings charges, accusing him of advising his client to flee when a guilty verdict was inevitable. Meanwhile, Brad and Denise decide where to take their relationship.
Stabler teams up with an new partner to investigate a sexual attack on Jessica DeLay, a sixteen-year-old girl who worked tobacco stings for the Department of Health and face an overweight young brother and sister who claim it was an act of vengeance for Jessica and her friend, Tommy Strahan, beating up their older brother Rudi for being fat. Stabler and Blaine arrest DeLay and Strahan, but when the two are released due to lack of admissable evidence, Rudi Bixton takes justice into his own hands.
When a proud and happy Ryan announces that Dana is pregnant, Jim warns him of Dana's upcoming hormone swings, and ends up dreaming that he is pregnant.
Veronica takes the stand in Aaron Echolls's murder trial, and is distracted during final exams while waiting for the verdict. Meanwhile, Keith takes new evidence about the mayor to Lamb, and Weevil asks Mac and Cassidy for help to pass algebra.
Jonas and his team must track down surface-to-air missles before they are smuggled out of Brazil after a deal with a drug lord falls through. Jonas gets help from a local boy who informs the team where the SAMs have been taken to be shipped. Meanwhile back on the base, Kim ends up causing even more trouble when she insists that the “Family Readiness Group” deals with what she deems more serious issues. Also, Williams tries to find a way to tell the woman he wants to marry that he is actually a Unit member and not a clerk on the base like she believes.
When a police officer with a gunshot wound to the head and uncontrollable laughter is admitted, House and the team are baffled. When Foreman begins showing the same symptoms, they race to determine the cause of the illness before Foreman's condition takes the same path.
Lorelai helps Emily while she's unable to see after minor eye surgery. Rory takes charge of Logan's recovery when he returns home.
The NCIS team must protect Ziva when a suspect dies while being in custody, and her tactic might be the reason why the person died. The things become much more dangerous when the suspect's brother kidnapps Jenny, and demands the release of his brother in exchange for Jenny, but he has no idea that his brother is dead.
Dr. Cox starts drinking after his decisions result in the death of three of his patients. The staff tries to cover for him at the hospital, while everyone tries to convince him how inspiring he is for them. Turk starts his new rotation with orthopedic surgery, but isn't so fond of his attending doctor's touchy-feely methods. Thus, J.D. and the Janitor attempt to help Turk find ways to bond with his new supervisor.
Mammoth Mutt, Tail Terrier, and Paw Pooch compete for temporary leader when Brainy gets put to sleep by sleeping gas.
Doug and Deacon discover they have more in common with each other's wives than their own, so they start hanging out with each other's wives as well. When Kelly tires of Doug, he ruins Deacon and Carrie's good time. Meanwhile, Arthur dispenses romance advise, and the recipient finds success simply doing the opposite.
Isis steals a magical pipe that can control animals and uses it to rob stores in Metropolis. When Ace and Krypto end up under her spell, Jimmy the rat has to fight her off.
Trump's children, Ivanka and Donald Jr. fill in for Carolyn and George for this task, which requires the remaining candidates to promote one of New York City's biggest tourist attractions.
Ephram discovers that Bright cheated on Hannah and confronts him about it. Irv takes Edna along on his book tour, where they meet his daughter Cassie. Reid is faced with expulsion from medical school for cheating on an exam. Harold confesses to Andy that he neglected to report Rose's cancer on the adoption application. Ephram tells Amy what happened with Bright, prompting her to confront him and force him to admit the truth to Hannah.