Dana is fed up because she attracts only shallow men. Jim is in trouble because his bowling team is missing one player. It just happens that Reverend Pierson is the solution to both problems. Unfortunately, there is a catch.
Dr. Brown tries to intervene when a bulimic high school champion wrestler puts his life in jeopardy for an important tournament. Bright is suspended from school after he fights with Amy's boyfriend Tommy. Linda suspects that that Andy is reluctant to move their relationship to a more intimate level because of her HIV status. Finally, Ephram is convinced that college student Madison is embarrassed to be seen with him.
Tony and Carol investigate when a 500-year-old skeleton in unearthed while foundations are being excavated for a hotel extension. However, underneath the body, they find two more modern corpses. And when a journalist vanishes, and the hotel is burnt to the ground, Tony suspects the suspect may be obsessed with Joan of Arc and killing imagined heretics.
A sportscaster must take on the responsibility of being a full-time dad when his teenage daughter moves in with him.
Eric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
The lives and relationships of a group of siblings and their estranged father Frank Gallagher on a rough Manchester estate.
The rambunctious human and alien duo must hunt down Dr. Jumba Jookiba's 625 other experimental creatures infesting Hawaii.
A fugitive geneticist and four of his creations search for others of their kind while attempting to stay a step ahead of a morally ambiguous government agent.
Manny falls flat at her gymnastics meet because she feels nauseous. When her sickness doesn't go away, Manny begins to worry it may be something more than the flu.
Larry questions a weatherman's ability to manipulate the media so he can have the country club to himself.
Hank commissions Peggy to create some artwork to satisfy the local zoning board after they approve a Strickland Propane expansion, but Peggy is humiliated when an art dealer promotes her as an illiterate hillbilly.
When George Michael is a rejected by a private school due to the family's reputation, Michael hires a publicist from his gym who he's been flirting with to change the public perspective of the Bluths. Meanwhile, Tobias is sent to Boston to reclaim his medical license.
Marge writes a romance novel with characters based on Homer and Ned Flanders that becomes a hit. Meanwhile, Homer gets fired from the power plant again and becomes an ambulance driver.
Jason breaks up with Phoebe when he finally learns her and her sisters are really witches. Meanwhile, Richard attempts to free himself of his family's karma, and Piper and Paige try to vanquish a group of Swarm Demons, the last on Chris' list of the most significant threats to Wyatt.
In a change from their usual excursions around Manhattan, Petrovsky convinces Carrie to have dinner at her place. The meal goes well, but ends abruptly when a mouse (smashed by Petrovsky) runs across her countertop. Later, the two get to talking about Samantha and her cancer, and Aleks shocks Carrie by talking about a friend of his who had died of the disease, making her realize the severity of Samantha's situation. Carrie doesn't appreciate Petrovsky's black and white viewpoint, and she walks out on him. Samantha's cancer treatments are going well, and she reacts positively to the chemo. Unfortunately, the procedure causes her hair to begin falling out. Samantha freaks out at this development, especially since she has Smith's big premiere coming up. A trip to a wig store proves unsuccessful, since none of the pieces can match her fabulous hair. After all of this, Samantha is forced to admit to both Carrie and herself that her condition scares her greatly. She then takes matters into her own hands, and decides to shave her head. Proving that chivalry isn't dead, Smith also shaves his own head in a show of solidarity, and the pair make the premiere in style. Charlotte and Harry's quest to conceive continues in vain as Charlotte's latest round of IVF proves unsuccessful. She tries to run away from her problems (literally) by taking frequent jogs in the park. During one of these runs, Charlotte meets Trudy Stork and her King Charles spaniel Princess Dandyridge Brandywine. The Princess is a showdog, but she doesn't compete due to a minor cosmetic flaw. Charlotte relates to the dog, and her perceived imperfections. Trudy sees the bond between the two, and gives Dandyridge to Mrs. York Goldenblatt. A quick namechange to Elizabeth Taylor Goldenblatt cements the dog's place as the newest member of Charlotte's family. Steve and Miranda discover that their apartment just isn't big enough for the two of them, Brady, Fatty and Scout. Steve suggests that the family move to Brooklyn, but the thought of leaving Manhattan doesn't sit well with Miranda. She grudgingly decides to take a look at one house in the outer borough, and though she doesn't immediately fall in love with the place, she does realize that moving to Brooklyn is the best course of action for her family. After some quick negotiations, she signs the deal, and the house is theirs. After another mouse invades Carrie's apartment, she calls Petrovsky to try and eliminate that problem. After he takes care of the rodent situation, the pair begin to talk, and come to an understanding, bringing them back together again.
Bette and Tina wait eagerly to see if Tina will get pregnant; Tim, unaware of her encounter with Jenny, invites Marina to a dinner party, while Kit tries to make amends with Bette.