Allison helps with the location of a missing child. Afterwards she gets a vision about the child's future and is not sure anymore what she should do to help the child.
When the entire population of Retroville is accidentally hit by Jimmy's shrink ray, the Space Bandits abduct everyone with the nefarious plan of marketing and selling them throughout the galaxy as living dolls.
After she beats him and his friends in a friendly poker game, Doug convinces his mother to try to enter a high-stakes tournament. Meanwhile, Carrie gets Spence to help her lose her accent to improve her chances of getting a promotion.
When Sam responds to a fatal stabbing at Crester's Textiles he's shocked to discover that it's the converted mill where he lives in 2006. Sam sets up a forensic investigation but Gene already has a hunch about the murderer. Sam believes he has to stop Gene from sending an innocent man down for life. But does he have more to learn about this world than he thinks?
High Stakes Poker action continues and Barry Greenstein starts to get involved! Daniel Negreanu, Doyle Brunson, and Ted Forrest join Greenstein for another High Stakes Poker cash game.
The Mala Noche strike again and it's up to the CSIs to bring them down once and for all. Also, MAJOR secrets are revealed about the characters and their love lives.
Now that Nolita has changed hands and Jack and Mimi are in charge, Nolita is nominated for an EPICURE Award. However, Jack soon realizes that Becky's restaurant is also nominated for the same award prompting a series of mistrust and hostility towards Jack for welcoming her back into his life. Seth finally discovers Jim's indiscretion and Ramon sees the Virgin Mary in a Prize Lobster.
Loyalties are tested, old feelings reignite, and the threat of loss becomes all too real when Kris faces her biggest challenge yet. Meanwhile, Pablo receives a call that will rock Raintree.
Racism comes to light at the high school when Alex, a new African-American student, wants to give a report on Dr. Martin Luther King, but his teacher argues that they have already covered that topic in class. When Martin inadvertently supports Alex's case, he falls victim to a hate crime. His car is defaced with racial slurs, and he refuses to wash it off until the culprit is caught. Meanwhile, for her own report, Ruthie attempts to recycle an essay that she wrote three years ago.
Almost three million dollars have disappeared from Montecito. The gaming commission has to clear Casey's licence and the missing money becomes an issue. Despite being dead, it seems Monica still gets Montecito in troubles. A live weather report is to be aired from inside the casino, when the weatherman gets an allergic reaction, allowing Mike to take his place for one night. Danny and Mike is to find the missing millions, and the thief, no matter if the thief is dead or not.
Dr. Ron informs Susan that she needs a splenectomy. Gabrielle and her arch-enemy Sister Mary Bernard finally face off in church. Also, Tom decides to apply for an empty position at Lynette's job, which leads to the arousal of past issues in their marriage. Lastly, Matthew and Danielle's relationship is found out by both their mothers, which leads to big repercussions later on for Bree and her past secret with Andrew last year.
Angel puts his own life at risk when an American is held hostage. Meanwhile, Sergio and Anna's relationship continues to grow, and Venessa tries to make up for her past.
Meredith and Cristina lie to each other and themselves about their relationships with McDreamy and Burke, respectively. George is given a hard task to expel a discharged and defiant woman from the hospital. Alex learns his fate after re-taking his medical exams. At the same time Izzie is trying to stop Alex from making stupid decisions when a patient that doesn't speak English is lied to by her coach. George, Cristina, and Alex compete in a hot dog eating competition.
After learning that God's greatest gift is life, Orel recruits his friend Doughy to help protect that gift. A library book, a graveyard full of dead townsfolk, and Orel's convictions spell trouble for the population of Moralton.
Grandad opens "The Itis", the only soul food restaurant in Woodcrest. White people didn't expect it. They also didn't expect high cholesterol, heart disease, and obesity.
Phoebe, in an attempt to move on with her own life, signs a lease for a new apartment, and Paige considers moving in with Henry. However the sisters are forced to remain under the same roof when a demon shrinks them and traps them in a replica dollhouse of the Manor.
Bartlet must deal with the possiblity of a nuclear explosion in California, Kate is keeping a careful watch on the election in Kazakhstan and China's response, Will is acting as the government's voice this week, and Josh is trying to keep his political version of Tourette's in check.
Shane opens her own styling business, and Bette loses her position as the sole provider for the family, forcing Tina to take up a job under Helena. Now back in L.A., Jenny introduces Moira to her surprised friends. Dana and Lara make plans to visit France while Alice still obsesses over Dana. Meanwhile, Kit is surprised by The Planet's new manager who wants to make some drastic changes to the place.
Logan and Barek investigate after a body is found in the ocean, having fallen from an airline wheelwell. They soon discover that she is just one in a long line of prostitutes to be beaten and murdered. Their investigation leads them to a nervous airline employee, but they just don't feel he has the courage or the violent nature to commit these crimes on his own. A family connection leads them to a second suspect, with a history of both being abused and being the abuser.