Mateo tries to get back with his old flame, Kelly. Unfortunately Kelly's mother Sylvia is in town and she doesn't suffer fools gladly.
Melinda investigates the haunting of a college student after the student sees a horror movie.
The team searches for a coma patient who had woken up after three years only to disappear.
The Friends start a prank war while staying at a hotel.
A reality show where a group of contestants are stranded in a remote location with little more than the clothes on their back. The lone survivor of this contest takes home a million dollars.
Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the activities of her current off-again ex-boyfriend. The doctor's are in the midst of a competition.
Jack tries to discover the identity of a body that has washed ashore. Meanwhile, Locke's camp is attacked by Ben's adversaries.
Ryan returns to Scranton but not to a warm welcome. He is making everyone in the branch come in on a Saturday to re-enter data into the new website. Michael makes it clear that Ryan is the reason they have to come in on the weekend. The rest of the staff aren't happy knowing a computer will be getting credit for all of their sales.
Gangland examines one of the largest and most violent gangs in Los Angeles County. It's estimated that 18th Street has more than 20, 000 members in Los Angeles alone with additional sets that extend all across the nation and even overseas.
While Clark seeks out Brainiac to force him to fulfill his side of their bargain and restore Lana, Chloe and Jimmy go up against the government.
In a change of pace, Sam and Dean decide to star in a violent, profane reality show named Ghostfacers. The show takes them to the haunted Morton Mansion, and they soon realize they're in over their heads.
Ryan gets the surprise of his life when Michael and Dwight travel to NYC to go clubbing with him and his friends. Back in Scranton, the staffers are upset that they have to spend Saturday working on Dunder Mifflin Infinity, and Jim's attempt to rescue them doesn't go as planned.
Dr. Cox had a patient that he hadn't been able to diagnose for two years, and he is back again. Dr. Kelso has to face a retirement board when his true age is revealed. Elliot and Carla try to find enough people in favor of Dr. Kelso to keep him as Chief of Medicine.
Betty plans to spend her 24th birthday accompanied by Henry, but Charlie's sudden appearance jeopardizes her plans. Meanwhile, Wilhelmina plots against Renee and Daniel's relationship by hinting at secrets from a hidden past in her sister's life.
A nightclub owner serving time in prison gets a temporary leave so that he can help Brass and Stokes investigate a double homicide with several connections to him.
Kovac is in Chicago looking for hospice-care work. Neela's aorta surgery has caused an infection in her patient. Abby treats a teen who has been beaten up. Brenner continues to cause problems for the ER staff.
When Don decides to promote Jack and make him his successor over Devon, Jack decides to give his old job to Liz because she always has his back. However, a turn of events concerning Don's health compromises Jack's promotion. Meanwhile, Tracy thinks that his son is embarrassed of his career because he did not invite him to fathers day at school.
Ash and Brock's old friend May, still training to become a Top Coordinator, visits Sinnoh for the Wallace Cup. Upon arrival at the Seven Stars Restaurant, they find out that only those who win a tag-battle against the restaurant's owners can eat there. Ash partners with Brock and win the double combat with a single move. Before Dawn and May's combat, Team Rockets steals all food from the restaurant. May and Dawn partner up and defeat both the Team Rocket and the restaurant's owners, the later by using Blaziken and Piplup together to create a fantastic fire/water combination. There is a cameo from Drew, Harley, and Max.