Frustrated by Lucas' growing popularity at school, Nathan searches for Lucas' weak spot, and finds it in Haley. Meanwhile, Peyton is furious with Lucas for submitting her drawings to the local newspaper without her knowledge.
Alvin is having to take James Mooney's caseload trying to stop Lulu from leaving for new job. Nick meets Sharon Diamond who was arrested for solicitation. Nick asks for help in what to recommend for Sharon A.K.A.: Tiffany Skovich who was working at a restaurant. Nick tells Tiffany Skovich to talk to the police about Mason and go to a shelter. Alvin tries to get Mason to stop using girls for money. Alvin goes to far looking for Tiffany before police get to the scene, leaving Nick to wonder why he isn't at LSP. Alvin fights Roger over pictures he took outside the restaurant where Mason worked. Roger other LSP board members feel Alvin went to far. Lulu is the new Director Legal Services of Pittsburgh.
When a Navy commander's body washes up on shore along with the bodies of two drug runners, Gibbs refuses to believe that the sailor who was killed was dirty.
Michael Kyle longs for a traditional life, but his day-trader wife Janet, gangsta rap-worshipping son Michael Jr., and brooding daughters Claire and Kady make his dream just that ... a dream.
Ms. Caine wants an operation to get rid of her cankles. Sean and Julia are still on the outs. Christian learns he's going to be a father. Julia steals Christian's brush to determine if he's the father of Matt. Sean and Grace learn that Ms. Caine has multiple personalities. Cara recovers and gets close with Matt and Henry. Henry develops feelings for her. Cara asks Matt to the prom. Henry tells Matt that he is going to confess to Cara what happened.
Jim wins a water-bed when playing bingo at a church fund-raiser. The pastor realizes Jim cheated, and talks to him about doing the right thing.
While Danny tries to find out the secret of Julian Kerbis who bought many chips but hardly even gambles, Big Ed stumbles upon his cousin in the casino. He is about to marry a girl he met few days earlier.
Andy's well-intentioned plan to give Ephram more free time by hiring college student Madison Kellner as a caretaker for Delia ends up making things worse when Madison treats Ephram like a child as well, and embarrasses him in front of Amy. Meanwhile, Andy's concern for Colin's alcoholic father blinds him to Nina's struggles with her divorce proceedings. Dr. Abbot continues to clash with his sister, Linda, when she tries to take over his office and the difference in their personalities and medical philosophies become alarmingly clear.
Eric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
A sportscaster must take on the responsibility of being a full-time dad when his teenage daughter moves in with him.
Mona and Dee Dee are half-sisters with the same father who didn't really know each other when they were little and are complete opposites, but as adults they live in the same apartment building and at least try to bond.
Toni's brother professes his love for Maya, but Maya wants to keep things casual; Joan frantically cleans her house to distract her from obsessing over relationship decisions.
A fugitive geneticist and four of his creations search for others of their kind while attempting to stay a step ahead of a morally ambiguous government agent.
Matt Lucas and David Walliams take a comic look at life in Britain. Their gallery of outrageous characters here includes Marjorie Dawes, Lou and Andy, and Bubbles.
Horatio hunts for the person responsible for a vicious attack on a woman who was lured to a vacant condo and beaten with a piece of lumber.
A power-hungry citizen seeks to manipulate the Commonwealth for his own gain. Dylan receives an unsettling view of his future from a prophetic alien.
Charlie and Alan go out drinking. Alan tries to reconcile with his wife. After that fails, they decide to confront the root of their issues, their mother.
Kim returns from Harvard to find that Nikki has rented out her room; T convinces the professor to join a pyramid scheme.
When Michael stays home from school for two days in a row, Ray suspects he simply has homework he hasn't finished. While everyone in the family has an explanation for Michael's sudden aversion to school, Ray decides the tough love approach is the way to go making Michael spend the day without television, games or comics. When Michael is forced to watch Ray work in his downstairs office, the sheer boredom leads him to finally confide why he doesn't want to return to class.