The lives and loves of four female friends: Katie, a doctor having an affair with a patient; Trudi, a 9/11 widow; Siobhan, a barrister; and Jessica, a commitment phobe who plays the field.
In this flashback episode, memories are looked back upon. Lucas surprises Peyton in Los Angeles and they talk. He asks her something and is left with a surprising answer. Meanwhile, Nathan's temper triggers up after a guy reminds him of his cheating in high school basketball games.
Does life exist on other planets? Astrobiology is a visionary new science that searches for life in space by combining the disciplines of astronomy, biology and geology. How did life evolve on Earth? What will life look like on other planets? These and other pertinent questions will be answered by a diverse group of scientists.
A mother's sudden paralysis during a indoor rock-climbing incident leaves her daughter injured, and House's new team looking for a cure. Meanwhile, House organizes his new recruits' Secret Santa gift exchange... with a few twists of his own.
Christian attempts to cope in the aftermath of a death. Colleen feels threatened when another talent agency shows an interest in Sean's acting career.
With the local council doling out money to the new young-mayor, Debbie sees a chance to buy hens and potatoes and give Chatsworth free egg and chips. Meanwhile, Shane falls for his perfect woman and it looks like she's fallen for him but when she takes him back to her place, the spare room at Lillian's; Shane's in for a bit of a surprise. Also, Yvonne has trouble with some yobs in the shop and things get a bit heated has she finally met her natch? And,when Stan runs down an old lady, he confides to Tom and Carrie that he should be wearing spectacles. To save his job, Carrie takes the rap, but when the old lady decides to sue, it might be Carrie who is going to get fired.
Kris sneaks back into town to watch Wildfire in a race. Junior sees her in the barn with Wildfire. Dani and Kris become friends, and Dani lets Kris stay at her new clinic. Junior is struggling to decide if he should propose to his girlfriend, Laura.
Paige gets a job in the fashion industry, but her relationship with Alex - who is being lazy after completing her education at Degrassi - is threatened by both Paige's job and Alex's attitude. At Degrassi, Manny reconnects with Damien, but the both of them clash over the issue of merging the Degrassi and Lakehurst organizations.
Kyle and Amanda's relationship hits a period of uncertainty after she makes a surprise visit home, but is uncharacteristically cagey about the reason why. Meanwhile, Jesse loses her patience with Kyle when he keeps putting off her training sessions.
Paul learns that Laura is infatuated with him when she attends her regular Monday appointment. Paul, however, is further shocked by the revelations Laura makes regarding a steamy bar encounter.
Huey and Riley listen to different perspectives on the story of their ancestor Catcher Freeman.
When Lacey starts up an 'Employee of the Month' program at The Ruby, Wanda tries to get Brent to do the same, but finds that she has some hurdles to jump before she gets the appreciation she feels she deserves. Hank's new hobby is knitting, much to Emma's dismay. Oscar also has a new hobby: writing for The Howler, and Karen and Davis have to keep him out of trouble.
Sebastian's life is in jeopardy when it turns out the fatal shooting of his former law partner was supposed to be a hit on him.
When a trio of sirens move in, their wanton songs pique Carl's attention.
When Stan's mom gets dumped by yet another boyfriend, she comes running to Stan for support, which he willingly provides (yet again). Francine, feeling threatened, seeks to loosen this umbilical cord, with Roger's help. Meanwhile, Klaus inadvertently gives Steve a fish disease called "ick."
Widow Old Amos announces that he has decided to get married again to his maid Patty. His friends are worried that she is just marrying him for his money. Robert manages to upset his family and the residents of the village when he refuses to let his children sing a song in praise of the Tories at the local church concert.
Zoey returns to PCA, hoping to tell Chase how she feels about him, but her friends have shocking news to tell her: Chase has recently moved away from PCA to find her. After Chase and Zoey get to meet, they agree to go on a "video chat date". Even with Zoey's communications problems and Chase's obnoxious roommate,Colin. Chase manages to tell Zoey "I love you". Zoey agrees too by returning Chase her own love. However, they wait due to the problems of having a long-distance relationship and decide to move on until Chase moves back to PCA so they can be together. Guest Star: Sean Flynn
Michael and Logan try to fool the housing lady into making a fake Chase in order to avoid getting a new roommate. Zoey accidentally gets Coco fired and tries to help her get her job back. Meanwhile, Dean Rivers hires Mira, the new dorm advisor. However, she has a problem: she steals everything that she sees. So, Dean Rivers fires Mira and Coco is hired again, but she isn't seen at the end of the show. Before leaving, Mira also steals Dean Rivers' car.