Jack searches for a safe place to land the plane when Logan gives orders to shoot it down. Hayes readies Bierko for a transfer to a secure facility, while Audrey receives some good news about her father. Logan becomes desperate as his plans start to unravel, but an unexpected ally at CTU turns the tables in his favor.
A girl from Jake’s school invites him to his first boy-girl party. Charlie and Alan help him get ready for it by giving him advice. Alan and Charlie get nostalgic and remember their first boy-girl party.
When a matchmaking company calls Ted claiming they have found his soul mate, he is forced to postpone his date when Lily asks for his help.
Everyone's ready to make their escapes across the high wire. Veronica and Nick realize they may be in over their heads. And Agent Kellerman helps Vice President Reynolds calm down before her debate.
Christine's former marriage counselor comes into the gym, leading to some awkward moments between the two women. When Christine mentions this to Richard, his cryptic reaction leads her to question whether it was in the counselor's best interest to encourage their divorce. Meanwhile, Matthew finds Christine's wedding video in a box of old photo albums, and Christine takes a trip down memory lane.
The vicious criminal Chopper Hadley, who has been back in the country for a week, is searched for by the team. However, Halford is viciously intimidated and the squad start to realise the full danger of their target. Desperate measures are used and Brian is sent undercover to get Hadley once and for all.
When Jordan wakes up to find J.D. dead beside her, she has no memory of the events from the previous night. Accused or murder Jordan will turn to her friends to help piece everything together.
A young boy, Caleb, starts following Hank around, making fun of him and generally annoying him. Hank isn't sure how to deal with such a young bully.
C.J. and Will both face uncertain futures as Bartlet and his staffers prepare to leave the White House to make way for the Santos administration.
Trinity is in danger of failing grade 6. Ricky comes to the rescue. Bubbles reveals that he has a fear of chickens.
Logan and Barek investigate a series of home invasions that result in grisly murders and their search leads them to local foster mother Chesley Watkins who had a series of young men going in and out of her home throughout the years. One of the young men involved in the home invasions was one of her boys, and while trailing the young man, Logan shoots a suspect who was brandishing a weapon at himself and Barek. When the suspect turns out to be a cop, Logan finds himself in the hot seat, and Barek sticks up for her partner, knowing that the truth is on their side. The investigation leads to Watkins as a suspect, and Logan is forced to deal with memories from his own past as Watkins plays on the weaknesses she sees.
When a new witness steps forward, Lilly and the team are prompted to re-open the 1984 shooting of a respected and beloved ER doctor who had a secret he had been hiding from his family.
Peter wants to top Joe, who just built a new home theater system, so he starts to build a multiplex in his backyard. In doing so, he discovers an Indian burial ground. He finds an Indian chief's skull and the Griffin house becomes haunted. Stewie gets sucked into the television and strange events follow as they try to get Stewie back from the poltergeist.
In an attempt to destroy the reputation of the Charmed Ones, Billie & Christy resort to trying to make the magical community see that the Halliwells only care about themselves. Meanwhile, Phoebe begins to lust after Coop; Paige cannot hear her charges' call for help; Piper becomes the perfect 1950s housewife.
Bree and Andrew finally reach an impasse in their relationship as tension has finally reached a critical point. Meanwhile, Ed finally fires Tom with the pressure from his wife. Lastly, Edie's private detective begins to uncover numerous details of Karl and Susan's relationship as of recently. Gabrielle is having a tough time keeping her servant in the country.
Marge goes on a cleaning frenzy before the housekeeper she’s won the services of comes to the house. One spot remains and she mixes a number of toxic cleaners together to tackle the job. The noxious mixture knocks her out and she wakes up suffering from amnesia. Marge is taken home and the family tries to bring back her memory. She starts to get back memories of her children and other insignificant things, but when it comes to remembering her husband, nothing he does seems to jog her memory. When he can’t get her to remember him, he tries to win her all over again, especially after Patty and Selma get her back out on the dating scene.
Bob is trying to prevent a rain of concentrated sulfuric acid that would destroy Mexico City. Homeland Security suspects two American scientists of preparing a bio-terrorist attack against the United States President and order David and Caroline to investigate.
Huff's father decides that he will extend his stay, and some family members feel he is wearing out his welcome. Lena asks Huff to address her alternative psychiatric therapy students. Byrd offends some people with his latest art project. Meanwhile, Russell ends up going on a drug-fueled bender.
Paulie finds public opinion turned against him after an amusement ride accident, while Chris tries to start a new life as a husband and father.
The staff attends to an intern from another hospital who has short-term memory loss. This intern, named Marshall, also has caused a car accident that involved a married couple, their unborn baby and the woman's parents who the staff are also treating. The pregnant woman is named Melanie and she will die but her baby may survive. One of the female interns meets up with a woman from her past who is planning on having a family of her own. Cristina is in a good mood although Alex, Izzie, George, and Meredith are having problems but in the meantime Burke hasn't forgiven Cristina for her late night faux pas. Meredith and Izzie are making fun of Callie's household habits and George and Callie are having a fight because of George's roommates. Addison is continuing to own Alex and he's upset about it. Denny has an outburst at Izzie and Derek has an outburst at Meredith.