While on the way to May's next Pokémon Contest, Ash and friends must stop at a nearby island to switch to ferry to the next island. They let their Pokémon out to play and Donphan, still as playful as ever, tries to play with some Rhyhorn, only to be chased by their parents. After being saved by Nurse Joy and her Meganium, Grovyle gets into a conflict with a wild Tropius and is beaten badly. Meganium heals Grovyle and Grovyle falls in love with the Herb Pokémon. However, it is later revealed that Tropius also has feelings for Meganium. Grovyle decides to have a rematch against Tropius to see who will come out on top.
Jackie meets the local star while at the salon with Fez: talk show host Christine St. George. Her new goal in life is to be Christine's co-anchor on "What's Up Wisconsin?", but breaking in to show business is harder than she thought it would be. She finally gets a job working with Christine, but it's not quite the job she wanted. Randy wants to take Donna away to a cabin, which makes her suspect his intentions; Red takes Hyde to his Lodge, and Hyde's intentions come under suspicion.
When someone soils the carpet in Michael's office, Michael sees it as a form of hatred towards him and realizes for the first time that not everyone may like him. Due to the odor of his office, Michael temporarily switches workspaces with Jim, and while there, Michael reminisces of his pre-management days, reliving pranks with Dwight that he and Todd Packer played on the staff. Meanwhile, Jim realizes why Kelly sits alone in the back of the office as he plays messenger for a childish flirtation between Kelly and Ryan, and Pam tries to cope with the day without Jim to make her laugh.
Clark reveals his secret to Lana, Jonathan and Lex learn the results of the senatorial election, and there is a tragic car accident on the highway that takes the life of someone Clark loves, forcing Clark to appeal to Jor-El for help.
When a worker exhuming bodies from a church dies a gruesome death from a pox-like disease, Hood joins an emergency medical team to trace and chase a virulent hybrid virus. Authorities scramble to avoid a pandemic. But Rachel risks contamination, and the pursuit takes on a personal urgency.
Earl tackles number eighteen on his list when one of his old friends is arrested. Remebering that he told an inappropriate story at his birthday party he must give him one great day to make up the the terrible one before he was sent to prison.
The women educate the men about interior design and decorating for the next task, while the men teach the women the technological aspects of computers. The women judge the geeks' newly-decorated rooms for the first task. After that, the beauties compete in a race to assemble a computer.
After reading about a dead man named Leon Corbe, who died during the construction of Kadic, Sissi decides to hold a séance to communicate with him. She manages to convince Ulrich to attend. During the séance, one of Xana's ghosts appears in the form of a four-armed monster. At first, it seem docile, but quickly gets angry and attacks. Ulrich leaves Sissi with Odd while he goes to tell Jeremie. Jeremie can't find an activated tower, which seems wrong considering the situation. As Jim patrols the hallways, he is picked up by an invisible object. Jeremie, Odd, and Ulrich arrive to spray it with a fire extinguisher, confirming that it's a ghost and implying that the super scan is broken. With the ghost on the loose, the group heads off to the factory. After they arrive, Aelita, Odd, and Yumi head to Lyoko. Odd looks for the tower while the other two head to The Carthage Region to fix the super scan. Meanwhile, Jeremie and Ulrich are left to deal with the ghost.
During the school physicals, Xana possesses the school nurse, Yolande, and has her kidnap Aelita. The rest of the group beats her to the factory, but has no way to get Aelita from the far more powerful nurse. Having no other choice, Jeremie decides to test out an experiment which will give a person the same powers as one possessed by Xana. To do this, he has to activate a tower like Xana. Jeremie's towers turn green instead of red. Odd volunteers, and is enhanced by a ghost of Jeremie's design. This allows Odd to fight the nurse effectively while the others deactivate the tower. This fortune doesn't last, however. Xana is able to take over Jeremie's tower, reversing the effect of the ghost to drain Odd's energy. And on Lyoko, Xana makes everything invisible. Now the group has to deactivate not only the original tower, but the tower that's draining Odd's energy.
The evil Jimmy clone is back, and he's reconfigured the cloning device to make an evil clone of the Earth with an alarming side effect – the real Earth is starting to disappear.
The contestants have to draw inspiration from their surroundings while outside in New York. The designers have a budget of $100 and one day to complete the outfit.
When both his job and arcade skills seem to no longer impress Dominic, Jimmy hopes getting entry into The Guinness Book of World Records will again make him cool in his son's eyes.
Russel knowing that Larkin and their unborn child's life is on the line he must stop Larkin from reporting what she knows. Sheriff Underlay is shot and drifts between the past and present.
Captain Hero's x-ray vision makes a housemate ill. Distraught, he seeks to give up his super powers.
Danny is on his way home after a long shift and finds Randy Williams subway surfing. Mac and Lindsay arrive on the scene and begin to wonder if Randy Williams died from riding on top of the subway. His death is even more suspicious after they examine the body more closely.
Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
When George finds out that Max is skipping school, he tries to be a role model by going to college, but no one takes him seriously.
When Duncan disappears with Meg's baby, Lamb must work with two FBI agents to extract as much information as possible from an uncooperative Veronica. Meanwhile, Wallace reveals the real reason he returned to Neptune, and Weevil and Logan make a breakthrough in their hunt for the rogue gang member.