Ed reports back to Mustang in East City, where discussion of Doctor Marcoh and the Philosopher's Stone leads to a duel between Ed and the colonel.
The Masters are called to Spelea, where they discover Lord Dactys and his warriors defending themselves from a Caligar attack. While King Randor mediates a truce between Lord Dactys and Ceratus, the Snake Men take advantage of the distraction to enter the Temple of Serpos, intent on awakening the Guardians of Old...
Thinking Unicron is defeated, Galvatron and Optimus Prime resume their battle.
After Mongo, a famous wrestler, takes ill at the hands of Proud Snacks, Oscar is forced to step into the ring to defend Mongo's belt. Oscar, now known as “Mama's Boy,” does so with the help of his tag-team partner, Suga Mama. Ironically, Mongo ends up having to fight Oscar to get his belt back.
Experiment #523 - Slushy A giant heatwave has struck Kauai. Lilo is trying to get Stitch to try something to escape the heat, but Stitch just refuses: He's a creature of habit, and won't try new things. As he tries to get a cold sofa, he activates Experiment #509, an ice experiment from the elemental series, who has frosty breath that can transform any town into a frozen one.
Young Elinor Carlisle, engaged to marry the dashing Roddy Winter, finds herself charged with the fatal poisoning of Mary Gerrard, her rival in love. Poirot has the job of saving Elinor, but the evidence against her is overwhelming.
Ash decides to head to Petalburg City for his next Gym battle. On the road, the gang runs into a group of Spinda. A pretty girl named Claire approaches, and Brock's reaction to her scares all the Spinda away. She is looking for her lucky Spinda, which has a heart-shaped mark on its face. Ash and friends offer to help her. Team Rocket tries to steal the Spinda using a vacuum, but the lucky Spinda fights back using Hypnosis and all of the Spinda escape. They also try disguising a Teddiursa (and later Meowth) as a Spinda to lure the real Spinda in, but fail. The kids track the lucky Spinda down to a flower garden, where they are met by the Spinda's owner—Claire's fiancée, Kain. Brock's heart is broken. Team Rocket shows up in a giant Spinda robot capable of repelling all the attacks of the Spinda. Brock sends out all of his Pokémon, and his Forretress destroys the robot using Explosion. Ash and friends wish Claire and Cain the best, and depart for Petalburg.
For the first time ever, Edina has agreed to stay home and spend Christmas with the family. Edina typically goes overboard by buying a huge tree and tons of gifts. Patsy is very upset that she cannot go away on vacation with Edina as they do every year, as she hates Christmas. Patsy has a flashback of unpleasant Christmas memories of her childhood. Someone somewhere sticks a pin in a Patsy voodoo doll, and she collapses in pain beneath the Christmas tree. Although Edina and Saffron ignore her, John insists that Patsy needs to go to the hospital. Once at the hospital, the doctors tell Edina that Patsy is very sick and that she may die. Edina and Saffron return to the house to continue their Christmas celebration. In the middle of the night, Patsy's estranged sister Jackie arrives to visit her. The following day, Edina and Saffron drop by only to learn from a nurse that Patsy has died, only they find out that it turns out to be Jackie instead.
Tired of living in the garage, Jr. looks for an apartment and enlists his buddy, John, to be a co-signer… except that John has to dress up and pose as Jr.'s grandmother for the realtor. When Jr. and Vanessa's families come to visit the couple's new apartment, Jay is shocked to find that her new grandchild might be living in a run-down building with yellow police tape around the entrance.
After Cate encourages Bridget to participate in extracurricular activities to beef up her college resume, Bridget shocks the family by landing the lead in the high school production of the story of Anne Frank. Rory's obsession with a dummy named Skeevy becomes a little unnerving for the Hennessy clan.
Experiment #458 - Finder Experiment #458 can find absolutely anything, so Lilo names him Finder. And when she takes him to show-and-tell, he's a huge hit, upstaging Mertle. Mertle is bitter, so she searches for something to compete with Lilo's show-and-tell. Unfortunately, she is unsuccessful. That is, until she sees Hamsterviel on planet Earth!
When Bernie lands the dramatic lead role of a stroke afflicted former track star, he has a hard time convincing everyone he has the chops to be a serious dramatic actor and reaches out to Angela Bassett for acting advice. Since Bernie is working and cannot care for the kids after school, Wanda must put the younger kids into daycare at her work. Upset at being stuck with a bunch of babies, Jordan leads a child rebellion where the kids escape daycare and wreak havoc on the office. Meanwhile, Vanessa pretends to be poor, so that Teri, a girl at school, will like her. But the plan backfires when Teri finds out that Vanessa is lying and that she is really Bernie Mac's niece.
Rush and Valens investigate the case of a cold-blooded killer who shot a young man trying to hitchhike his way home to Philly from Atlanta.
Michael loses his short-term memory, which Lucille uses to her advantage. Gob attempts to use the family yacht before Michael sells it. George Michael and Maeby attempt to see an R-rated movie about cousins having an affair. Buster and Lucille 2 take "the next step".
Ed and Al uncover a conspiracy involving the Tringham Brothers' father, his involvement with the red water and the disease that's stricken Xenotime.
Fee's quest for a smoke leads her to become entangled in a terrorist plot to stop human development in space by initiating the Kessler Syndrome, destroying the Toy Box in the process of saving the ISPV 7 space station from destruction.
The Masters of the Universe have won a great victory in driving the Snake Men away from the Mystic Mountains. Entering a local tavern in search of rest and refreshment, Man-At-Arms comes face-to-face with his estranged brother, Fisto. Old grievances rise to the surface, and Man-At-Arms accuses his brother of being a deserter during the Great Unrest. But this moment is soon interrupted as Buzz Off and Stratos discover that Webstor has eaten Ambrosia and has transformed him into a large spider-creature with incredible power! When the Masters are trapped by Webstor, Fisto is called into action...
The purpose and meaning behind the endless war is revealed.
When a recent string of thefts cause a global shortage on a certain type of doll, Kim decides to investigate, despite the fact that she already has a lot of extra-curricular duties to perform. When she finds out that the Bebe-bots are back and bent on creating an army of their speedy species, with Bonnie as their queen, Kim must rely on some recently acquired experimental shoes in order to save the world; though that isn’t going to stop her from doing a few of her extra-curricular tasks along the way.
Experiment #199 - Nosy Nani wants a job at Mr. Jameson's hotel, so she invites him and his son Keoni over for brunch to prove how much 'Aloha Hospitality' she has. Unforunately, Experiment #199 has been activated, and he seeks out enemy's secrets. However, a glitch in his programming has made him into nothing more than a gossip. So now Lilo and Stitch must stop him blurting out the family's secrets to Mr. Jameson and Keoni.