When Eric learns that he must undergo double bypass surgery, he calls a family meeting to share the news but loses his nerve at the last minute and decides the group should go bowling instead. His odd behavior surprises everyone, especially Annie who grows more concerned when Eric's brother-in-law Hank shows up unexpectedly. Meanwhile, Robbie pesters Kevin about helping him make a parking ticket disappear. Lastly, Lucy continues to question whether Kevin has ever been with another woman.
Jeff is still trying to decide whether he should cheat on his girlfriend Julia with Wilma, or not. While his friends try to help him, Jeff is no match in this debate for "devil woman" Wilma. She knows every argument that Susan (the expert in getting her own way) has ever used. Jeff paints himself into a terrifyingly extreme conversational corner, until he blurts out that the reason he can't have sex with Wilma is that his girlfriend is dead...
Ray writes a eulogy for his father Frank, who hasn't died yet. In the eulogy, he tells a childhood story about watching his tough dad pet the family bunny named Hoppy. Unfortunately for Ray, Marie reads the eulogy and gets offended when she learns that Ray hasn't written one for her.
The double murder of a social services worker and a deputy mayor lead the detectives to suspect a couple who may have a grudge against the social worker for taking away their children. When they learn that the social worker had taken special interest in a child prodigy being considered for admission to a prestigious, accelerated school, they examine both the boy and his obsessive father.
As Fred and Gunn search for Angel, Wesley continues his affair with Lilah and conducts his own, more fruitful, search.
Larry, Cheryl, Jeff and Susie encounter a ""nanny from hell"" whose reign of terror is thwarted by ten sponge cakes. Larry commits a ""penis faux pas"" after a pool party, and Richard Lewis seeks immortality from Bartlett's Quotations.
Sydney must decide whether her mother's goodwill gesture was sincere or an attempt to kill her. Will witnesses Francie discussing her restaurant plans with a man whose affiliations are questionable, and Sloane is made a full partner in the malevolent Alliance of Twelve.
Cole and Phoebe both fall under the spell of the Siren, who lures husbands to her and entrances their wives to follow with the intent to kill, leaving Piper and Paige to figure out how to save Phoebe. Piper, upset with Leo because he does not understand the challenges of being pregnant, and Leo, frustrated that Piper does not realize the demands of being a Whitelighter, have their personas switched magically by their unborn child.
A freak accident at a Globicide-owned amusement park leaves Bob unable to use his mouth. Out of compassion (and at the advice of their lawyers), the people at Globicide build him a robotic suit with limbs that he can use to perform his duties.
D.I. North investigates when a girl is snatched from a wood, but the confession of a local sex offender complicates matters. Detective Chief Superintendent Walker is little help, as he has worries of his own.
Lindsay's murder conviction tries Rebecca, who's handling the appeal to the Supreme Judicial Court; Jimmy's kidnapping case turns confrontational, in and out of court.
Advance Preview It's Thanksgiving week in 1963, but, in the wake of the JFK assassination, no one feels thankful. Even Meg's selection as a Bandstand regular seems hollow to her---especially since best friend Roxanne (Vanessa Lengies) wasn't chosen. And the resentful Roxanne isn't going easy on Meg (Brittany Snow). Meanwhile, East Catholic's football team has a hole at running back without J.J. (Will Estes); and Helen (Gail O'Grady) gets together with the worldly Rebecca Sandstrom (Virginia Madsen) at Temple University.
When Spike reveals the identity of the mystery man she's been dating, Emma is shocked to learn it's her teacher, Mr. Simpson. When her mother cancels out on girls' night to go out with Mr. Simpson, Emma and Manny decide to sneak into the seniors' dance. Elsewhere, Spinner and Jimmy compete for hockey tickets.
A disparaging remark about his wife sets Johnny Sack off on a vendetta. Meadow decides to do volunteer work at the South Bronx Law Center; Furio hosts a housewarming party for the gang; Silvio and Chris make an offer to an old-time hit man named Lou DiMaggio; and Tony and Carmela find themselves at odds over the family's bill-consolidation strategy.
The Andromeda picks up a group of refugees who have been subjected to psychological and physical torture.
Jackie, Jade, Uncle, El Toro and Paco track the talisman power of the Rat (reanimation) to Mexico. Finding the rat in an acient Aztec temple, El Toro accidently causes the rat's powers to accidently bringing a statue of the God Quetzalcoatl to 'life'. God Q mistakes Jade for the Goddess Chiuacoatl. In attempting to save Jade, El Toro is mistaken by God Q for Xoloti who takes souls to the underworld. God Q captures out heros on the outskirts of a nearby village. Daolon arrives to take the rat for himself. Jade manages to change the marking on Daolon's forehead to resemble that of Xolotl and convinces God Q that Daolon is the real enemy, not El Toro. Grabbing the rat from Daolon, Jade runs into the village and animates the Super Moose plush toys being sold there. The Super Mooses free Jackie and the others. God Q defeate Daolon and learn how he was brought to life, and agrees to be returned to a statute.
Someone has stolen X Middle School's beloved mascot, Lobstee the Lobster. Time is running out for both Lobstee and the Bocce Team, and the key to finding him before time runs out might be X's resident psychic, Alistair Greystone.
A wormhole opens in an office floor and the science professor disappears into the wormhole, never to be seen again. Josie Trent experiences an extremely interesting first day at Blake Holsey High when she and her new roommate, Corrine, travel through the same wormhole. Could this give an indication of exactly what occurred to cause the mysterious incidents at "Black Hole High?"