In the twelfth Treehouse of Horror episode: Hex and the City – While on a day trip through Ethnictown, Homer's bumbling catches the ire of a gypsy, who curses Homer's family and friends into receiving nothing but bad luck. House of Whacks – in this mixed parody of Demon Seed and 2001: A Space Odyssey, Marge buys an automated house and customizes it with the Pierce Brosnan personality, who falls for Marge and attempts to murder Homer. Wiz Kids – In this Harry Potter parody, Bart and Lisa go to a school for wizards, and Lord Montemort (Mr. Burns) uses Bart to capture Lisa's magic. Guest star: Pierce Brosnan and Matthew Perry.[20]
Counter Terrorist Unit agent Jack Bauer is assigned to protect presidential candidate David Palmer from a potential assassination attempt. Unfortunately, his daughter has disappeared and someone within CTU may be involved. Mandy seduces Martin Belkin, a photographer headed for a meeting with the Senator.
Clark begins experiencing "vision problems" as his x-ray vision begins manifesting. Meanwhile a mysterious shapeshifter is going about town using his or her abilities to steal and get others in trouble.
Rory surprises everyone by agreeing to make her debut at a ball, and Lorelai finds herself attracted to a changed man.
Now that CLS has expanded its circle of operation to include all people needing legal aid, not just minors, Nick is given a case surrounding a retarded man, Malcolm Dempsy, who wants to remain living on his own. Though his mother fears for his safety, his next door neighbor and friend is a drug dealer, she has no proof and therefore the court will not remove him from his apartment. When Eddie, the suspected drug dealer, is murdered, Malcolm is accused of the murder and Nick must work to find the real killer - a search that puts him back in the world of drugs. Far more crucial to Fallin & Assoc. is the fact that Jake has hit another lawyer with his car and faces felony charges if the man dies. Burton Fallin is concerned that Jake's reckless driving has put the firm in danger of being sued and Jake feels the lawyer Burton has hired to defend him is more concerned about what's good for Fallin & Assoc. than what's good for Jake Straka. So, he embarks on his own investigative work to try to clear his name.
An accident causes a mess on Frasier's carpet and the destruction of Martin's chair. Meanwhile, Niles gives piano lessons to talented Roz and not-so-talented Daphne.
Sipowicz is hailed a hero after killing the man responsible for Sorenson's murder. While Lieutenant Rodriguez teams up with another precinct to investigate the robbery of his mother, the squad investigates the murder of two men affiliated with NYU.
While investigating the murders of four teenage girls, the 15th squad discovers the shocking truth about the disappearance of detective Danny Sorenson.
J.D. has finally earned the spot as brightest student, but he's got competition: Nick Murdoch, who seems to be nicer, friendlier and has a better butt than him. But even J.D. can't hate the guy, for he is so nice. But he is surprised when he finds Nick sitting in a corner crying because he can't take the pressure of medical internship. Meanwhile, Turk is having problems at the operation table and doesn't tell Carla, who keeps bothering Dr. Cox about it. And Dr. Cox gives Turk a very unique suggestion on how to calm down before surgery.
Max, with the help of Kal Langley, undertakes a dangerous journey as he seeks to learn of the fate of Tess and his son. Meanwhile, back in Roswell, Isabel and Jesse must face the negative reactions of their parents and friends to their impending marriage.
Charlie discovers that Jennifer's ex is a woman. He becomes jealous when watching her be affectionate with Caitlin, something Caitlin dismisses until Jennifer kisses her on the lips. Claudia and Paul's divorce settlement may be affected by the mayor's bickering with Judge Claire.
The mayor prepares to debate his opponent, while Charlie and Jennifer, his opponent's campaign manager have been dating for 3 weeks. The mayor wants Charlie to dump her, but he doesn't. When the mayor visits Charlie in the middle of the night to share something that may be damaging to his campaign, Jennifer may have overheard it. Meanwhile, Paul and Robin become involved; Paul thinks it's a relationship, while Robin thinks it's a fling.
Jenny insists that Ally should go out with Glenn, and Ally insists she doesn't have a crush on him. The three are assigned to chair the telemarketing case. They have a very hard time with the main plaintiff, Claire Otoms, a purple-haired, flashy-looking lady who lives in a 'colonial house'. Raymond, knowing that if the judge listens to her he'll rule in his favor, takes the deposition to the court. Claire keeps drifting from the questions, for Ally's desperation. But what appeared to have gone so bad turned out good. Coretta convinces John that he must look good to cause a good impression, and John ends up dressing a fake muscle suit to try to get rid of his weird-women magnetism. Ling and Nelle 'compliment' twin babies on the street. The mother of the babies - the Massachusetts governor - is so flattered by the compliments that she offers Ling a judge position. Overwhelmed, Ling makes a purple robe and starts to give more-than-quick sentences.
Rommie sets out to extract an informant, but winds up stuck on a planet with a strong hatred and fear of Androids.
As Arthur prepares to undergo heart surgery, he asks Carrie and Doug to bring him his sleep mask. While digging through Arthur's closet for the mask, Carrie finds a box which contains an extensive scrapbook of her old finger-paintings, report cards, and school photos that Arthur has been keeping. As she is flipping through it, she finds an acceptance letter from Florida State University – which she has never seen before. Meanwhile, Doug makes friends with a quirky stranger in the hospital and soon regrets it.
Marie and Debra set up Amy with Gianni to get Robert jealous so he'll want to get back together with Amy but their plan backfires when Amy and Gianni hit it off.
Greg is jealous when he meets Todd, whom he considers the perfect dad. All Greg had to compare himself to before was Jimmy, but now there's another dad who actually plays with his kids, instead of playing golf with his buddies. Worrying that he's as awful a parent as his own father, Greg has another daydream that Older Sam dedicates a toast to the man who made him who he is today -- Todd. Since Older Sam can't remember Greg's name and even daydream Todd pointed out that he's bad, Greg decides to be a good dad too by going out with Kim and Sam and Todd and his family, rather than with Jimmy. But Todd is so active that it only takes two days of non-stop activities for Greg to want out. Since Greg needs Jimmy to make himself look good, Jimmy invites the ultimate white trash family, headed by redneck patriarch Earl, to Greg's barbecue, so he can have someone who makes him look good. Greg confronts Todd and asks him when he ever gets any alone time, but learns Todd considers alone time any
Event: CENTRAL AMERICA 1488 A.D. Sydney and Nigel are in Central America with a guide, Carlos, tyring to get into an Aztec pyramid. They succeed and recover a ruby-eyed statue. Carlos betrays them, tying them up and taking the statue. They manage to get free and go after him, only to find him dead, and the opened box nearby. They take the box and try to escape by train, but Carlos was working with mercenaries who also want the statue. A thief on the train tries to steal the statue and also ends up dead. Sydney belives the statue has a curse and vows to take it back to the pyramid. With the aid of the NSA man who gave her the coordinates, she and Nigel get back. The head of the mercenaries tries to take the devil doll but ends up dead as well, as a ghostly image of an Aztec priest rears up. Sydney seals the doll within the pyramid once more.