House and the team rush to treat an ailing college football star in time for the patient to compete in NFL tryouts. But when the patient experiences an onslaught of varied and unusual symptoms, the team has trouble reaching a consensus on how to effectively treat him in time. Meanwhile, Foreman’s brother Marcus makes a surprise visit to the hospital.
The Pawn Stars have a chance to buy a key from the 16th or 17th century, but this key doesn't just open doors, it shoots bullets! Will they use this rare antique key-gun to unlock a deal - or shoot themselves in the foot? Then Corey and Chum meet a dumpster diver with a life-size Power Ranger. Will Corey use his super hero powers to conjure up some cash, or will the dark forces compel him to cast the Ranger out? And later, Rick has a chance to buy a trophy presented to Jeff Gordon for being one of NASCARs top five drivers. Will Rick throttle up his cash register for the trophy, or will the deal go screeching into a pit stop?
The gang are left in shock as the unthinkable happens - Mickey is conned! Some lowlife rips him off by selling him a useless mobile phone online. According to the age-old laws of grifting, when a grifter is conned he's guaranteed a run of bad luck. What will the gang do if Mickey loses his mojo? They head to Eddie's to drown their sorrows, only to find it heaving with customers. It seems Lady Luck has switched her allegiance and the chums need to do something to restore the balance.
15 year old Amy ends up pregnant after one night at band camp, throwing her whole life upside down. It doesn't help that she's now going to school with that guy.
Buddy creates an underwater-themed cake complete with live fish for a local aquarium.
One of Ichigo's classmates, Hayami, mentions that Ichigo doesn't deserve to be in the same group at the Sweets Princes due to her lack of skills. However, Hayami and the rest of Group F continually slack off in class and she, however, seemingly doesn't care about sweets. Ichigo has a feeling that something isn't quite right and found out that Hayami was originally in Group C (but dropped to Group F after her sickness and fever during the final exam). Even worse, Hayami is currently planning to transfer out of St. Marie.
Stan puts down liberal social programs because he thinks they are a waste of money and gives Francine a hard time for lending a helping hand at the local homeless shelter. When Stan develops a nasty addiction and needs help, he suddenly has a change of heart.
When an epidemic hits Lark Rise during harvest time, help comes from an unlikely source.
Amy and Ty are at odds over his purchase of a vintage motorcycle while Caleb goes off to a rodeo in Montana despite Ashley's growing concerns about his life on the circuit.
Pressed by Coburn to state his intentions, Bill gets his family to stage an elaborate rally announcing his candidacy. He isn't so lucky when an audit uncovers insurance discrepancies caused by his multiple wives. To protect his secret and save his candidacy, he ends up asking Don to take the fall, and moves up his announcement by three days.
George gets a new job, a new girlfriend and even a cage to transform in.
As Fitz and Ming debate the merits of their insemination plans, the doctors revisit their past entanglements. Fitz finds himself challenged by the demands of a psychotic patient. Chen is called away to Brisbane to visit his dying grandfather. And Ming comes to terms with her surprise pregnancy and what it means for her future.
Robert and Nora get to work as guest chefs in Scotty's struggling restaurant to boost business, Kitty puts her idea to run for Robert's senate seat up for a Walker family vote, and Sarah reaches a point of frustration with Roy but is quickly rewarded for speaking up.
Coach Cleveland comes to the rescue of frustrated parents by taking a group of delinquent teens under his wing. With the help of Cleveland Jr., he creates a new club dubbed "The Crazy Eights," and hopes that it will keep the kids on the straight and narrow. However, he is soon mixed up in bad business, and only the "Crazy Eights" can help him out.
Homer blows off Marge to buy a lottery ticket and winds up winning the million-dollar jackpot. Fearing how Marge will react if she finds out the reason Homer missed their date, Homer keeps his newly inherited fortune a secret and spoils his family with “anonymous” gifts. When Bart finds out, he and Homer spend the money like it’s going out of style, including buying front-row to tickets to see Coldplay in concert.
Brian gets a gig writing for a teen magazine about the average American girl, but when he starts trailing Meg for research he discovers that her desperate attempts at dating have led her to a guy in the slammer. When Brian tries to expose Meg’s secret to the family, he finds out that her boyfriend, Luke, has broken out of jail and has been hiding in the Griffin’s house.
Gaby and Angie challenge each other's parenting skills, Susan befriends a stripper and takes her under her wing, Lynette and Tom argue the merits of their new therapist, and a concerned Bree keeps a watchful eye on Orson for fear he may take his own life.
True, Lulu and Ryan must mentor incoming freshman for a day. True decides to take her little buddy, Molly, to work with her, although she is shy. While there, Molly criticizes True's new dress after being asked her opinion. True later learns to accept it, and makes a better dress with a new fabric. Meanwhile, Lulu's little buddy, 35 year old Babs teaches her about life. Also, Ryan's little buddy, Nate, gets him into all kinds of trouble, until he finally gets him busted.