After a federal witness is killed, the US attorney arrives at the Lightman Group to take the next witness in line, Reynolds, into protected custody. Cal feels that the US Marshals Service cannot protect Reynolds, so he takes him "hostage" and demands that he be able to run the investigation into the witness's death. During his investigation, he finds out that while undercover Reynolds did drugs and killed a man and wants to keep it a secret to avoid prosecution after he finds out that his handler (Alicia Coppola) did not properly report the event. Through his own undercover operation, Cal records the handler admitting that she led Reynolds to believe that everything was all set legally, and the US attorney subsequently takes her into custody. Meanwhile Loker and Torres discover that the original witness was killed after the cell phone that his mistress provided was tracked to his safe house's location.
Claire is determined to get to the bottom of the Sorority Rush attacks on her own, until H.R.G. intervenes only to realize he may be the source of her troubles. Meanwhile, Peter's new ability is a perfect fit for his job and gives him the opportunity to help Emma accept her new life. Elsewhere, Sylar's battle at gaining full control over Matt's body escalates with potentially dangerous implications at stake.
Horatio Caine calls Las Vegas CSI Ray Langston to come to Miami when a severed leg found in the Everglades is discovered to belong to a girl who went missing in Las Vegas a week earlier. The crossover continues on CSI:NY S06E07 Hammer Down (II) and CSI: Crime Scene Investigation S10E07 The Lost Girls (III).
The 1986 murder of a jockey is investigated after his body is discovered in a mass grave for horses. The victim disappeared shortly after losing a race that he had planned to be his finale before retiring.
A well-meaning struggling writer decides to lead a sort of double life by pretending to be a private detective, using the methods he read about in old detective novels.
William Garrow is now a celebrated Old Bailey barrister and, encouraged by Southouse, he defends the case of the infamous Monster, a man who carries out a series of stabbings on young ladies across London. As a result, Garrow's popularity diminishes with the public and the press. However, Renwick Williams, the accused, is described by Garrow as a 'lecherous libertine' and his defence is not easy. Garrow's friendship with Lady Sarah grows closer, a fact which does not go unnoticed by her husband, Sir Arthur.
Ichigo finds all three of the Sweets Princes also have accompanying Sweets Spirits. On a trip to a local preschool, Ichigo notices a little girl named Ringo that seems to be having trouble making friends, and promises her that she will make a cake that will help her to make friends with everyone else in the class.
Susan believes that Katherine may be Julie's assailant. Angie invites reluctant Bree and Orson to dinner. Gaby struggles to home school Juanita. Lynette has her own suspicions about who attacked Julie. Angie confronts Nick.
When Brian begins dating an older woman, the family begins to make fun of him. After Brian's new fling breaks her hip, he gets the pleasure of becoming her errand boy.
After attending to the concert of a teen superstar, Stewie discovers a surprising secret about the singer. Meanwhile back at home, Chris tries to prove the existence of the Evil Monkey.
Lisa becomes very attached to an 8-year-old boy who she witnesses being crushed by a ride at a fair. Meanwhile, Andy and David try to get a VAD (ventricular assist device) for one of their patients.
An investigation into a deadly case of mistaken identity reveals a secret love triangle and an underworld web of intrigue.
Larry is forced to embrace his feminine side; Cheryl competes for a Seinfeld role; a law officer has an unusual name.
After Cleveland has "the talk" with Roberta, Cleveland Jr. becomes scared and takes a vow of chastity. Meanwhile, Rallo becomes a church greeter.
Kitty is devastated when she must face the aftereffects of her cancer treatment. Meanwhile, Nora makes an unexpected friend; and Scotty's father shares some shocking news about his marriage.
Declan sets his sights on Holly J, but will her bad attitude cause him to stop chasing her?
Holly J falls hard for Declan and finally realizes the fuss about this "love" thing.
Believing Ofdensen is dead, Dethklok is forced to become their own managers while dealing with repairs to the destroyed Mordhaus and trying to plan their biggest concert to date. Their efforts are stalled however when a past acquaintance cuts off their unlimited financial freedom to get revenge against the band.
An apologetic Miley plans to make up for the fiasco that Hannah caused at Lilly's last birthday with a special girl's night out. Unfortunately, she ends up stranded in the middle of nowhere on the big day, which leaves Jackson in charge of keeping an increasingly upset Lilly busy until Miley arrives.