The NCIS team investigates the disappearance of a Petty Officer who is the sole witness in an upcoming murder trial.
In the National Museum of Nuclear Science and History, there's a small vial that once contained a wildly popular drug called Radithor. Don Wildman discovers how this doctor-approved "cure-all" end up destroying countless lives.
Everyone if having fun in the paddling pool, until Stripey pulls the stopper out.
When Ian, Gabe, and Suki have dreams about a mysterious yellow elevator, they search for it in the tunnels. They observe a new student being brought out of the elevator. He becomes Ian and Gabe's new roommate and can infiltrate dreams. They discover Cornelius Tower's office (Tower Prep's founder) and investigate. They take some items from Cornelius' office and bring it to the observatory. Conner then escapes and reveals, in Ian's dream, that he is a "scout". They find that Conner took the things from the observatory, but left a picture of Cornelious Tower with a young child. Ian realizes that the young boy is himself.
Kensi connects personally with a discharged Navy Intelligence officer suffering from post traumatic stress disorder who is the sole survivor of a deadly dispute being investigated by the NCIS team.
Depressed after his breakup from Courtney (Jenny McCarthy), Charlie goes to see his psychiatrist (Jane Lynch).
It's Christmas in Hawaii, but instead of celebrating, Five-0 is negotiating a hostage situation when the man who killed McGarrett's father resurfaces. The murderer, Victor Hesse, threatens to detonate an explosive that he's strapped to Chin Ho's chest.
After seeing the attention Eddie gets in his theatre club, Don decides to join up.
After years of begging Mike and Frank to let her go on a pick, Danielle finally gets her chance. The three head out to visit a major collector with a barn full of hidden treasures. Next, Frank agrees to fill in for Danielle at the shop while she hits the road with Mike. In Pennsylvania, they pick the oddball home of two eccentric characters, and Danielle comes up with a winner when she tracks down a century-old hotel that's been vacant for years. Rooms full of furniture and a valuable pinball machine await.
Lily and Marshall receive shocking news that has a profound impact on the gang. Ted begins his duties as best man for an old friend's wedding.
Mike tries to find a perfect gift for his very first Christmas with Molly.
Chief of Police Tommy Delk (guest star Courtney B. Vance) assigns Major Crimes a seemingly minor case involving the armed robbery of several medical marijuana dispensaries. But when one of the robberies turns into a murder, the case becomes a test of Brenda’s readiness to move up in the department.
Kenny Armstrong is outraged to learn his daughter has been attacked in the park and, accompanied by two of his friends, sets off to find the culprit. However, the trio's assault on the man they suspect proves more violent than Kenny had intended, and while his cohorts are adamant that informing the police of their actions would be disastrous, his urge to confess grows.
Miranda and Penny find it impossible to be normal in a session with a psychiatrist.
The friends pretend to run businesses, but Timmy and Finlay do not have enough money to buy a toy and set up rival shops - until they realise it is better working together.
Paul's nefarious plan for Wisteria Lane is put into full effect. Juanita discovers that she isn't Gabrielle's biological daughter, and Bree invites Keith (guest star Brian Austin Green) to move in with her, whilst Tom is confronted about his past indiscretion with Renee.
Bo finally learns the identity of her mother – and that those closest to her have been keeping secrets. No longer sure who to trust, Bo decides to track down “Mommy Dearest” alone, in order to extract the truth about her own origins once and for all. While everyone frantically searches for Bo, Dyson visits an ancient Norn, a wish-granting, tree-dwelling crone, where – in order to protect the woman he loves -- he makes a sacrifice that may change his relationship with Bo forever, as she prepares for a final face off with her deadly mother.
Homer ends up in the Springfield penitentiary after getting caught bribing an official; an FBI investigator offers Homer a way to reduce his jail time.
Despite Francine's warning, Stan gives Steve a gun for Christmas; Steve accidentally shoots Santa.
Stewie’s favorite thing after his teddy bear, Rupert, is Christmas. So when he hears that Santa is making an appearance at the mall, he begs Brian to take him so that he can tell Santa in person what he wants for Christmas. Brian begrudgingly takes Stewie to the mall, only to get the brush-off from Santa. As a result, Stewie and Brian travel to the North Pole to find Santa and teach him a lesson in holiday cheer.