Bill gets a new home security system, Nicki throws a birthday party, new neighbours move in, and Margene meets her mother-in-law. Meanwhile, there's a break-in in Bill's hardware store.
The Santos campaign meets up with Rock the Vote and lots of musicians are around for a star-studded episode. Helen gives a lecture to MANA (a National Latina Organization, formerly Mexican American National Association) but her heritage doesn't help her when trying to deliver part of the Santos campaign message. Toby is being pressured by the Attorney General, Blake, to reveal his source and it's affecting his relationship with his kids. He tries a little psychological warfare of his own to get Blake to back down. Toby is also giving Josh campaign advice which includes plans to increase courtship of the Latino vote. Elsewhere on the campaign trail, it's Halloween and Toby's kids and Santos' kids are dressing up for the occasion.
Wedding plans occupy the girls, and Shane is reunited with her family. Helena pitches in to have Carmen's family flown to Canada, Jenny and Max drift apart, and Kit has stunning news. Peggy Peabody reconnects with her daughter -- but does it last? Finally, Tina has second thoughts about Angelica's custody arrangements, leading Bette to take desperate measures to be with her daughter.
Goren and Eames investigate the death of Eric Newsome, an urban explorer who was found in a water tower. During their investigation, they learn that Eric had been looking into the files of Dr. Everett Janns, an OB/GYN who had examined his sister Nikki's boyfriend Drew's mother years earlier when she had been carrying his sister Lisa. Lisa Ramsey was born with spina bifida, and Victoria Carson was suing her primary OB/GYN, Dr. Dominic McKenna, with a wrongful life suit, charging that he did not perform the necessary tests needed to establish whether or not her child had spina bifida, which would have influenced whether or not she had an abortion.
When a poison-soaked towel turns up at the station, Lilly re-opens the 1973 case of a murdered female college tennis star.
Vilgax tries to get the Omnitrix for himself while Grandpa Max's strange past becomes known, causing a showdown between Vilgax and the Tennyson family.
With the outbreak-mutant situation the Turtles feel they have to deal with and Donatello sick his brothers leave him with Casey and April for care. But Donatello is not sick but in the last stages of a second mutation.
April Fools Day: Ned, Cookie, and Gordy team up to fool the king of April Fooling: Vice Principal Crubbs. Moze tries to break up with Seth, but he thinks it's a prank. Excuses: When a dog actually eats Ned's homework, nobody believes his excuse.
Lilly is ecstatic when she gets two tickets to a Hannah Montana concert and invites Miley to accompany her. Miley refuses, saying that she doesn't like Hannah Montana. Miley's dad, Robby, tries to convince her to tell Lilly her secret: That she is Hannah Montana. When Lilly finds out what Miley's been hiding, will she treat her the same? Jackson won't take no for an answer when he wants to borrow money for his big date. But his dad keeps refusing to be his personal ATM.
When no one watches Keely's investigative reports show Pim comes to the resuce by offering to help make her popular amongst her viewers again but Keely realizes that Pim is just abusing her to make money and goes back to making "real news" with Phil.
A labeling mix-up between animal musk and after shave causes Harold a lot of grief when he goes to meet his fiance's family. Red gives up on parallel parking and tries his hand at perpendicular parking. Bill helps Red clear the trees that have grown around an abandoned boat. Mike tries to guess the word 'parent' in the Word Game. Red converts an electric blanket into a table warmer and makes a spill-proof submarine sandwich.
On their way to Omashu, Aang, Katara, and Sokka meet a group of nomads who show them a shortcut through the "Cave of Two Lovers". But when the group becomes trapped in the cave, it's up to Aang and Katara to save the group by trusting in love, possibly questioning their relationship. Meanwhile, Iroh gets a lethal rash so Zuko and Iroh head to a small Earth Kingdom town for help, hoping their real identities will not be discovered.
Mr. Whiskers is excited because there is an audition taking place for a play in the Amazon, though his comments on the subject causes Brandy to decide to enter as well. However, when Margo sabotages Brandy's audition by messing with her drink, Brandy only manages to become the understudy while Margo gets the main role; though Gaspar makes a proposal to Brandy that may just help her get the position that she feels she deserved.
When Brandy realizes that she promised to participate in a firefly event with Whiskers on the same day Lola Boa bought tickets to a concert in the Amazon, Brandy decides to try to figure out a way to lie to Whiskers in order to get out of her prior engagements. However, when Brandy decides to just leave Whiskers and head to the concert, Whiskers becomes worried because he thinks Brandy may have been abducted by the fireflies, so he heads off to rescue her.
Raven must deal with entertaining both her boyfriend and her boss, Donna Cabonna, on the same night.
Everyone becomes obsessed with card collection when Coco lays magical eggs filled with cards.
A girl who is unable to walk or talk becomes a human portal for a demon.
Vlad is back, only now he's afflicted with a serious case of ecto-acne, a direct result of the college lab accident with Jack and Maddie. To ensure Danny helps him find a cure, Vlad infects Sam and Tucker with his disease, and Danny turns to Clockwork for help. Danny convinces Clockwork to let him go back in time to make sure the accident that injures Vlad never happens. Unfortunately, when he changes the past, he changes the present. When he arrives back in the present day, Maddie is married to Vlad and living in Wisconsin, and Jack's a ghost named Jack Plasmius! Now, Danny must go back in time for a second time to ensure his parents get together, but when he does, will that mean ecto-acne doom for Tucker and Sam?
Fellow con-man James Whittaker Wright III enlists the help of the Hustle crew to avenge his legendary grifter grandfather's treatment by Cornfoots Merchant Bank. Posing as enterpreneurs and investors they try to get back at the bank by a massive con. But have the Hustle crew forgotten just how devious James Whittaker Wright III can be?