After Mort bowls a perfect game, and Quagmire gets a key to the city by performing CPR, Peter notices he has nothing to be proud of. He then attempts to achieve fame by setting the world's record for most nickels swallowed. However, a slight miscalculation leaves him blind with nickel poisoning.
Jarry worries that Bullock and George Hearst will side with Montana on the annexation issue and a showdown looms between Wu and Lee. Andy Cramed holds his first religious service, though he doesn't count on Tolliver's participation.
Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.
When Stan forgets his anniversary, he arranges to have 20 hours of Francine's memory erased, but the CIA temp on duty accidentally erases 20 years. Francine, having reverted to her wild child days, moves into her old apartment with Hayley as a roommate, and ends up going to a festival with Hayley's boyfriend. Meanwhile, Steve asks a good-looking girl out, but needs his wingman, Roger, to "jump on a grenade" for him and date her ugly cousin.
When a person who was killed right in front of Phoebe comes back from the dead to blame her, she becomes guilt-ridden and vulnerable, creating an opportunity for Zankou to steal the Book of Shadows. Meanwhile, Paige has a new charge who knows nothing about magic, and Piper and Leo attempt to plan Chris's first birthday party.
"The World's Most One-Sided Fistfights" get wild at Mardi Gras. Benjamin Franklin grapples with historical figures like the Wright brothers and Mahatma Gandhi in "Educational Wrestling Federation." Oprah Winfrey fulfills all her viewers' fondest wishes...almost. A man in a public restroom encounters the terror known as "Dumplestiltskin." "12 Angry Little People" deliberate a crime most heinous.
Bubbles pretends to be a spaceman when the boys buy a rocket set. Ray reveals Lahey's secret and Lahey goes off the deep end.
A surprise guest shows up at a sad event as Bette gets stunning news about her job. Tina goes into a surprisingly difficult labor, Jenny finally reaches breaking point over her painful childhood memory, Alice struggles with her jealousy, and Peggy Peabody lays down the laws with her daughter, Helena.
When the body of a man is found and it soon becomes obvious the body has been moved, Eames and Goren investigate the death of Walter Czabo, whose wife has been sleeping with a decorated former police officer who happens to have close ties to Deakins. The suspects start piling up, starting with Frank Adair and leading to his controlling publicist, but Deakins is reluctant to go after his friend, who wields a lot of local influence, without good, hard proof.
Rose requests a trip back to the day her father, Pete Tyler, died. Reluctantly, the Doctor agrees, but he realises he has made a mistake, when Rose saves Pete from being run over by a car. This has now changed the timeline, and Reapers are transposing themselves all over the Universe. However, this time, the Doctor doesn't have a plan…
During a museum robbery, a partnership is formed between Catwoman and Penguin. But when Penguin double-crosses Catwoman before she can double-cross him, she and Batman have to stop Penguin before he unleashes his true plan: harnessing the power of Ra!
Jermaine returns and joins the Warriors as a Wudai Warrior, which is more advanced than a Xiaolin Apprentice. Omi is discouraged that Jermaine is ranked higher than him, and they constantly confront each other because of it. Jack soon learns that Jermaine's master is Chase Young, who doesn't know Chase is on the side of evil. Upon hearing this, the Warriors rush to notify Jermaine before it's too late. However, because of his encounter with Omi earlier, Jermaine refuses to listen.
After Jack inadvertantly releases the world's most biggest and powerful spiders, the Warriors, Jack, and Chase Young temporarily team up to stop the spiders before they proceed to consume the world. Kimiko, Raimundo, Clay, and Jack are captured while Chase and Omi escape. To look for an answer on how to defeat the spiders, they combine the Fountain of Hui and Eagle Scope. Will Omi and Chase be able to find the answer and put an end to the spiders' reign?
After the terrible injuries sustained in the last race, Hot Shot cannot finish the final race on his own... Leaving Koby to enter the tournament as Hot Shot's driver.
Six years in the future, an emotional Captain Archer and the crew return to Earth to face the decommission of Enterprise and signing of the Federation charter.
A human isolationist leader threatens to destroy Starfleet Command unless all aliens leave Earth immediately.
A dangerous felon escapes when a prison bus crashes and the FBI has reason to fear he's intent on revenge against the witness whose testimony put him in jail. However, finding the elusive killer proves to be a complicated challenge. Don teams up with Agent Billy Cooper, his former partner from the FBI's Fugitive Recovery Division, and Alan worries that Don's going to return to a more dark and obsessive time in his career.
Plankton tries to steal the formula, but slips and sues Mr. Krabs. Mr. Krabs hires a lawyer, but his lawyer slips and is hurt, so SpongeBob must try to help Mr. Krabs win the case by trying to open a briefcase that has something very important in it.
Mr. Krabs complains that his back hurts, so SpongeBob and Patrick buy a new mattress and Squidward tries to take credit for it. They give the new mattress to Mr. Krabs, but Mr. Krabs put his money in his old mattress, which SpongeBob, Patrick, and Squidward must find while Mr. Krabs is at the hospital.