While on vacation in Mexico with Emily, Lightman becomes involved in the case of a missing American woman, who is a single mother on vacation with her daughter. Upon investigation, Lightman learns that the mother got herself involved with an illegal fertility broker and he manages to find her just in time. Back home, Foster investigates D.C.-area hospitals with Lightman's rival, Jack Rader. They try to uncover the reason that five people have grown gravely ill after receiving blood transfusions.
Lily and Rufus decide to move up their wedding to the next day, but will someone or something come between them before they become man and wife? Chuck discovers a secret that Carter has been keeping from Serena. Dan and Vanessa are pulled into one of Georgina’s schemes. Blair is suspect of Bree and shares her concerns with Nate.
A wealthy businessman brings his teenage son, who is suffering from inexplicable stomach pains, to Princeton Plainsboro and insists on having Dr. House handle the case. The father of the patient believes the karmic penalty of his financial success is that he is victim to personal tragedy, and that the answer to his son's medical mystery lies in a reverse of fate rather than medical treatment. Meanwhile, Foreman and Chase prepare to present information on the Dibala case.
Haley is thrust into the spotlight and storm of Nathan’s growing scandal. Against her better judgement, Brooke allows Julian to continue working with Alex. Millicent gets a new job, which may cause trouble for Mouth. Meanwhile, Clay and Quinn grow closer.
When an Arctic explorer is killed during a polar expedition, the mysterious circumstances of his death take Castle and Beckett from the penthouses of Park Avenue to the halls of the CIA. But Castle's delight at the case's many twists and turns soon turns to frustration as he realizes that their elusive killer might just be fooling them all.
Julien is horrified when the baboons' dance routine is getting more attention than his own.
A chance encounter reunites Gaby with her sexy ex-lover and gardener, John Rowland; Bree contemplates a weekend getaway with Karl; Lynette and Tom break the news to their kids that she's pregnant again; and Susan is convinced Angie's son is responsible for her daughter's attack.
Hank attends a university mixer and consoles his jilted assistant; Charlie celebrates his first talent signing.
An 18-year old in need of a double-lung transplant, struggles to survive as the team runs into an obstacle that may prevent her from being eligible for the procedure.
Dexter is hampered by his neighborhood's increased vigilance due to vandalism, his temporary inability to drive himself anywhere, and his admiration for the killing technique of the artful Trinity Killer.
Chevy Chase and Dan Aykroyd move to Quahog. Brian and Stewie find out about their secret agency. They are told that there are Russian Sleeper Cells all over US. They go talk to Mayor West, and find out he is one of the sleeper cells. They follow Mayor West to Russia where they disable a nuke aimed at the US.
The men and boys in Springfield become obsessed with Ultimate Punch Kick and Choke Championships, a violent sport where fighters inflict severe pain on each other. When Marge and her friends stage a protest against the sport, the show's promoter embraces the controversy and challenges Marge to a match, promising to shut down the competition if she wins. She begins to train with rhythmic gymnastics, but her family step in and get her professional martial arts help to give her a real chance at winning.
Larry makes an enemy of Christian Slater at Ted and Mary's anniversary party, but gets his payback while at a restaurant with an old flame. Meanwhile, Larry's doctor gives him his personal number and soon regrets it.
There is trouble for Don and Sal in giving their clients what they ask for. Meanwhile, Betty hosts a fundraiser.
The 2004 murder of a teen at a juvenile detention center is investigated. The boy was wrongly sent to the facility and was killed before Valens could get him released. Meanwhile, Lilly reconnects with former flame Eddie Saccardo, a narcotics officer.
Discover how a brass band, a WWII bomber and a vintage racing car contributed to the construction of one of the world's biggest airports.
Kitty, Robert and Nora struggle to accept Kitty's cancer and to come to an agreement on the best possible treatment, but as they prepare to share the news with the entire family, a surprise visitor from afar makes the burden a bit easier to bear.
Alli discovers the joys of photography.....and the consequences of taking naked pictures.