When a doctor comes to New York to search for the missing daughter of her drug-addicted sister, Faith and Bosco focus their attention on the child's stepfather, a New Jersey cop, after they discover that the girl was taken by a man in uniform; Tatiana returns home; Jimmy spends some quality time with Joey. The crossover starts on ER S08E19 Brothers and Sisters
While drawing up their will, Greg and Kim have a difference of opinion on who should get custody of Sam in the event of their deaths. Kim wants Jimmy and Christine to have him. Though Greg thinks Jimmy is too irresponsible, he ends up deferring to Kim's wishes. When they tell Jimmy and Christine about it, Jimmy wonders how they expect a mooch to raise three kids. He learns that Greg's life insurance policy will handle that. But since Greg only agreed to trust him with his son and not his money, the funds were entrusted to Greg's sister instead. Jimmy is insulted that Greg feels he's too incompetent to manage his finances. Against Greg's wishes, Kim decides to give Jimmy $1500 of their tax refund to invest to prove his mettle. After a failed attempt at playing the stock market, Jimmy takes the entire $1500, plunks it down on a wet suit and scuba diving lessons, and starts up a golf ball retrieval service, fetching balls that golfers hit into the lake then selling them for profit. Greg b
Event: AN-NAJAF, PERSIA 422 A.D. Mac Hollingsworth, an old-school relic hunter, leaves a key to Pandora's Box to Sydney in his will. She and Nigel travel to Baraq, where they are befriended by a local conman and petty crook, Ahmid. With Ahmid's help, they get into the palace where Pandora's Box is secreted...disguised as harem dancers. The palace is controlled by Colonel Montoya and his henchman Hauer. Sydney finds the hidden door the key opens, but she and Nigel are captured. Montoya opens the Box and is incinerated. As eclipses and earthquakes plague the land, Hauer forces Sydney and Nigel to decipher a clue to re-seal the Box. They do so, then manage to stop Hauer from selling the Box.
J Street has become an Atavus hybrid, Renee rushes to locate an antidote.
Eric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
Dr. John Becker goes through his daily routine of being a doctor, stopping at his favorite diner, and other various situations, all the while hating life and everything around him.
When Carrie starts wearing her hair in a bun, Doug tries to figure out how he's going to tell her that he hates her new look.
Marie gets upset when she hears Ray calling Debra's mother, "mom". Ray tells Debra that maybe she should start calling Marie "mom". When Debra does so in front of Lois, she gets upset because she doesn't think that Debra should be calling Marie "mom" since she isn't her mother.
Ally and Victor return from their Bermuda trip. Ally feels their relationship is in crisis because they weren't able to connect without Maddie around. Victor is being sued by his former girlfriend for breach of contract. Ally discovers that Victor is a painter and never told her. She's angry, but not as angry as when she sees his painting of her with cellulite. Nelle and Wilson team up against a woman who was blackmailing their client in order not to come public with a tape of their lovemaking. Richard obsesses over Liza and has Claire do the talking for him through a hearing device, afraid she's going to turn him down - and even more afraid she'll say yes to him.
Angel's hotel is infested with demonic slugscreated by the spell he used to alter Sahjhan.
Flex thinks that he and his boss Stacy are hitting it off, but what he doesen't know is that his best friend Duane has been secretly dating her. It's hard for them to hide it from Flex but when they both have to go on a buisness trip together Duane takes it to the extreme. Meanwhile that Flex is out of town Breanna and Spirit throw a party. Arnaz brings Natasha over and Breanna once again gets jealous. She tries to stop them but when their about to have sex all Arnaz can think about is Breanna. Also a boy named Lewis tries to get with Breanna. At the trip Duane can't take it and tries to stop Stacy and Flex from having sex only to reveal his relationship to Flex.
When the mother of a teenage girl is found dead the daughter becomes the prime suspect. Jordan is convinced of the girls’ innocence and seeks advice from an unlikely source to save the girl from prison.
In an apparently tranquil Lancashire village, Lynley investigates the mysterious poisoning of vicar Robin Sage.
Dar faces his biggest test yet in his struggle to defeat the Lord of Darkness.
After her break-up with Aaron, Kim agrees to join Stevie in trying a speed-dating service. Meanwhile, Nikki works at Andell's club and catches Professor Oglevee on a date with another woman who turns out to be married. While on a date, Stevie frets over the fact that she doesn't act very feminine.
Joan engages in surprisingly risky behavior after she begins dating a younger man, Chris. However, her friends urge her to re-consider the relationship after she inadvertently takes ecstasy at a night club. Meanwhile, Toni hires William as her attorney and tries to monopolize all of his time with trivial matters.
Doggett catches someone in the X-files office trying to steal documents pertaining to Mulder's sister. The intruder is a severely scarred man who blames his disfigurement on Government conspirators. He claims the source of that information - and, in fact, the one who helped him gain entry - is Mulder. Although he refuses to divulge the missing agent's whereabouts, the mystery man has enough knowledge of the X-files and its history to lead Doggett to suspect that he just might be Mulder himself. Scully's fears for the safety of her son are elevated when he is injected with an unknown substance. With the mystery surrounding William becoming even darker, Scully must allow herself to send him away for his own safety.
Inspired by a cartoonist who speaks at the school as part of a career day assembly, Bart creates a comic book series based on Homer and his anger problems, which turns into a popular Internet cartoon series called Angry Dad. Homer finds out about this and is at first outraged, but after talking to his family, he decides to try to become a less angry person.
Ruth continues to help an injured Nikolai recover, but her patience is tested when she discovers just how he broke his legs. Brenda's escapades help her to write, but her feelings about being engaged grow more muddled--especially after Billy's release from the hospital.