The team investigates when young Carly Hunter disappears while walking home from school one day. While processing evidence found at the scene, Warner realises that the little girl has leukemia, and they need to get her home as soon as possible to begin treatment. Despite the ransom drop going wrong, the detectives are able to find the little girl thanks to evidence O'Halloran finds at the scene, but as she tells her story to Stabler and her mother, it soon becomes clear that her kidnapper is someone very close to home. Stabler and Warner end up becoming hostages when the kidnapper approaches Jake Hunter directly.
While looking for smuggled weapons at a shipyard, Tony and Ziva disappear and it's up to NCIS to find them. Abby tries to find them by tracking down their GPS chips, but they seem to be out of reach.
Paul recruits Denise to help him defend a cancer patient who used his wealth to guarantee he would not get a placebo during a drug study. Meanwhile, Alan goes too far in trying to convince the senior partners to promote "Hands" to partner, and Denny finds himself falling in love with a woman he meets at a charity event.
The CSIs investigate the brutal murder of a man who was learning how to pick up women at a hot nightclub. Meanwhile, Horatio tries to help out Marisol, Eric Delko's sister, who was arrested on drug charges.
Robin accepts Ted's invite to a friend's wedding, but thanks to Ted, the couple may never make it down the aisle.
Charlie sees a therapist to learn how to deal with Alan's emotional insecurities.
After a team from Atlantis goes missing, the expedition finds itself in the middle of a Genii coup.
The whole family gets stuck together in a snowy mountain cabin and the guys find a pregnancy test, but they don't know if it belongs to Crystal or Olivers new girlfriend.
The spirit of the Dr. Charles Walker (from "Penny For Your Thoughts") is back and after Allison's daughter Ariel.
After a car accident in 2006, Sam Tyler was up in 1973. Sam's 21st Century attitudes make him a fish out of water in this world of clunky technology and old fashioned policing. And nothing seems more alien than his new boss, DCI Gene Hunt, who believes in gut instinct and, all too often, sheer brute force. Then Sam discovers a connection between a murder in 1973 and the kidnapper in 2006. Could solving this case be the key to getting home?
On the run with Rich, Laura encounters a mysterious person who claims to know the origin of the creatures. Meanwhile, Miles fears the worst when two of Caitlin's friends vanish at the beach.
Monica's old suite seems to be haunted, causing troubles with the new residents. Sam makes a bet with Paul Logan, a rival casino host - who's the best casino host/hostess there is? Delinda faces problem with the health inspector at Mystique, but seems wrongly treated. Meanwhile, Mary decides to take advantage of the ghost situation and starts a "Haunted Montecito Tour."
Kerry comes to Kris with an opportunity to audition for a hot sauce commercial. She wants to pass, but decides not to when she realizes how much the money will help her and Raintree. When she has no chemistry with the actor she must kiss, the director grabs Junior to play the part, and the kiss reignites their relationship. Junior becomes partners with Pete on his new club, and begins to get acquainted with his mother Isabelle. Dani buys two horses to start her own stable against Davis, and Pete is getting more involved in his family's life to the chagrin of Charlie.
After Stan and Roger have a rough day, they get into a fight that leads to a "Freaky Friday"-type switcheroo where they get a taste of life in each other's shoes. But after the excitement of a new life stales, they face each other's problems as Roger is under pressure at work and Stan yearns to be needed. The swap gets out of hand as the family starts to crumble.
The squad is assigned to protect workers installing a pipeline. Meanwhile, Mrs. B is AWOL in Hollywood mixing with some questionable characters and Bo tries to run on his prosthetic leg.
Gabrielle kisses Tom and Lynette is not happy and drives a wedge in her friendship with Gabrielle. Paul attacks Mike. The housewives become more suspicious of Betty and her family. Andrew is trying to blackmail Bree, but Bree gets some assistance from Susan's ex, Karl.
After Brian has a near-death experience in the hospital, he decides to lead a new life. He ends up getting a nightly singing gig with Frank Sinatra Jr., but his new lifestyle doesn't last very long. Meanwhile, Meg, after joining a new after-school group, pretends to be a lesbian.
Caitlin has paid up the credit debt she accrued a long time ago and is free to go, so she quits her job. Meanwhile doppelgängers of the gang show up in the mall because of the mischievous Trisha, Caitlin's ex-best friend.
All eyes are looking forward to the Leo McGarry/Ray Sullivan Vice Presidential debate. Meawhile, Santos is trying not to catch his children's cold and he visits his home in Texas and continues to campaign. Jorge Santos, the Congressman's brother, may cause some problems at a gathering.