After deciding that leaving town would be for the best, Hope gets pulled back in after Josie comes up with a risky plan to close the Malivore portal. Elsewhere, Alaric and Dorian make an alarming discovery about Professor Vardemus, while Rafael learns some upsetting news about Landon's future.
An official truce is announced but complications quickly arise, threatening the lives of humans as well as Bloods.
Suddenly on his own, Desmond calls on his mother for help. Danika urges Michael to think bigger. Mila tries using her strength for good.
The government struggles to contain and understand the outbreak. Kaylee interviews Luther's ex-wife while Danika pays her sister a visit.
Michael continues to prowl for victims while Luther struggles with a traumatic loss and painful accusations. Also, Kaylee makes a connection.
Luther connects with a Washington insider who has a plan to keep society from collapsing. Ava sets out to get proof of the DNS internment camps.
As Michael and his followers settle into new accommodations, a tough-talking general takes control of the DNS. Also, Luther witnesses a brutal act.
Desmond's health worsens, forcing Luther down a dangerous path. Later, Luther receives a surprising offer and Michael lays down the law.
Luther's testimony rattles a few cages. Desmond and Amélie investigate an unsettling noise. Danika and Michael hit the town.
Luther pleads with the DNS to bring in Michael alive, but other pursuers have less peaceful intentions. Meanwhile, Danika's urges grow stronger.
Following an urgent trip to the Arctic, a scientist and his friend are quarantined with an illness that soon escalates into something sinister.
Midge struggles with Susie taking on a new client. Joel meets a mystery girl, Mei, who is as frustrating as she is intriguing. Abe initiates a new project with a group of young beatniks. Midge and Joel deal with their divorce.
Rose and Abe move into less than desirable new digs. Midge struggles with her act as Shy's tour kicks off. Joel and Mei spark a connection.
Christy and the ladies rally around Tammy when she has trouble adjusting to early release from parole. Also, Bonnie is disappointed when her perfect birthday gift for Adam gets a lukewarm response.
Dean goes off on his own to take on a case. Meanwhile, Castiel has an idea of how he can help Sam track down God.
The makers celebrate the holidays with Nick and Amy by, first, making a wreath out of unconventional materials for the faster craft, then building an interactive lawn display to showcase their favorite holiday for the master craft.
Gus brings girls over to the beach house; Nilsa and the other roommates try to figure out how to release Kortni from her tonsil demons.
Wade pretends to be dating Caroline to avoid being set up on blind dates by Delia. Also, Ben and Michelle throw an anniversary party for themselves, but have issues with the catering.
When Hans Holzer visited the Ayers-Allen House in Metuchen, New Jersey, in 1960, he found entities dating back to colonial times. Now his case file is reopened, and the team discovers the spirits there may have a more ominous origin.
With luggage still in tow, 16 new designers are greeted at the iconic TWA Hotel at JFK airport. Paired off, they receive their first assignment: to create innovative jumpsuit and cocktail looks inspired by humanity's continued push into space exploration. They have $400 per team and two days to complete the challenge.