In the Season 5 premiere, moonshine is in demand and the law is on the hunt. Included: Tim faces a dilemma that jeopardizes his legit business; Jeff, Mark and Lance aim to double their profits; and Josh and Bill find themselves on shaky legal ground.
The grand opening of Chicago Med's emergency department is interrupted by victims of an elevated train crash, pushing the staff to their limits.
The S.H.I.E.L.D. team discovers dangerous truths about the ATCU, and Wards plans to destroy S.H.I.E.L.D. take a surprising twist.
Liv consumes the brains of a death-obsessed illusionist who was murdered in cold blood during a magicians convention in Seattle. As Liv and Detective Babineaux investigate the case, she uses her new skills to help narrow down the suspect pool. Meanwhile, Blaine gives Liv some interesting news, and Ravi makes a decision but things dont end up going quite as planned. Lastly, Major continues to distance himself from Liv.
Boden's new neighbor asks him for a favor that could have serious repercussions. Severide is upset when he's treated like a candidate by Patterson. Cruz is visited by a gangbanger who knows his brother. The team responds to a call that involves an 18-wheeler; and is thanked with tickets to see Rush.
The Huangs are hosting Thanksgiving this year, and Jessica is determined to out-do her sister who has hosted in years past.
When one of her oldest adversaries targets the Ice Kingdom, Marceline rushes to Simon's rescue.
Stewart convinces Dean he cant keep using his celebrity if he really wants to be a regular guy. But when the brothers find themselves in serious trouble, Deans fame might be the only way to bail them out. Meanwhile, Debbie gets an assistant, and ends up being more of an assistant to her.
Brian offers to use NZT to capture the FBI's Ten Most Wanted criminals in two weeks, in exchange for Naz giving him his own personal work headquarters at the agency. Also, the secretive nature of Brian's new life working for the Bureau creates a rift between him and his father.
Five foes from Marceline's past come back to cause trouble for the Land of Ooo.
Jane and Weller go undercover as a world-class assassin couple to prevent deadly information from getting into the wrong hands. The intimate assignment draws them closer than ever. Meanwhile, David embarks on a solo mission to win Patterson back, and Carter clashes with Mayfair over how to handle a dangerous individual.
Gordon and Barnes continue cleaning up Gotham, and Gordon comes face-to-face with one of the city's most dangerous hitmen, Eduardo Flamingo. Meanwhile, Nygma and Penguin cross paths again, and Bruce pressures Galavan into handing over the name of his parents' murderer.
In order to hunt down the brutal murderer of a grifting seducer, Castle Beckett must investigate New Yorks elite. Meanwhile, Castle plans to surprise Beckett on their one-year wedding anniversary.
Everyone is on high alert when Valco boss Brendan O'Connor descends on the store. Plus, pharmacist Brian asks Margaret for help with an audition.
Wander convinces a down-on-his-luck villain to spend a day looking on the bright side of things instead of collecting the souls of others.
Sharon and the team investigate a murder during the taping of a reality competition show pitting married couples against each other. The case has a profound effect on Sanchez, bringing back memories of his late wife. Meanwhile, Rusty meets Slider's lawyer.
When Scheana and Katie bust Lala for lying about a modeling job in Italy, Lisa Vanderpump turns the table on them for picking on the new girl. Scheana worries her marriage may be in danger when it's revealed that her husband has been keeping secrets. Tom and Ariana try adulting, Jax and James compete for Lala's affection and Tom Schwartz makes a big step towards committing to Katie.