Marc is riding high, his career is taking off and his relationship with Jen seems to be going well. However, Marc turns out to be his own worst enemy as he sabotages a TV guest spot and ruins his relationship at the same time.
Alan must face the consequences after revealing his identity to Larry.
With Derek away, Meredith spends time with Amelia and finds out her true feelings about her time in Seattle. Bailey deals with the ramifications of her actions and Callie receives devastating news. Meanwhile, the residents panic after hearing that one of them will be fired
Stefan and Elena become stranded in a remote location, after escaping from Markos, and he gets philosophical about her relationship with Damon. Damon sets a trap for Markos. Bonnie admits that she's been keeping the truth about the Other Side from everyone. Caroline witnesses an unthinkable act of violence by one of the Travelers.
A bad day causes Penny to reevaluate her life choices – including Leonard. Meanwhile, Howard and Bernadette struggle to care for Mrs. Wolowitz, and Raj gets relationship advice from Sheldon.
When Frankie has his first taste of alcohol and Rachel wants to go on birth control, Joanne and Jack are left at odds.
Mary teams up with Catherine to deal with Henry, whose deranged behavior puts Francis at risk. Elsewhere, Bash resolves to destroy the Darkness after meeting a boy who survived the horror; and a devoted Lola tries to protect Julien.
Riley is looking forward to meeting Philip’s sister from England, but her excitement soon vanishes when it becomes obvious that Georgie is less than impressed by her brother’s taste in girlfriends. Danny’s contract negotiations are in jeopardy when Bonnie tangles with the Rangers’ new general manager, Valerie.
David, Gill and their son Freddie hope Noel Fitzpatrick can help their Labrador Scooby, who has a life-threatening tumour in his leg. The vet goes to extraordinary lengths to save the life of Tiger the cat after his heart stops during his recovery from an operation, and when a lurcher called Otis brought in with shotgun wounds, Noel must extract the bullet before working out how to save the animal's leg. Plus, will a pair of tights help a French bulldog walk again?
Hannah and Tom have happy news, and Derek's dad Anthony goes on a date with Tom's nan. But matters of the heart are taking a downward turn for Kev, who calls on his brother Cliff for help.
A man's online accounts are hacked by a woman he met on Facebook in the Season 3 premiere. After meeting Zoe on Facebook, she begins demanding passwords and hacking accounts.
Taylor is tempted at a party and the Cassidys go to Christian therapy. Meanwhile, Teryn and Chad finally renew their vows and Tori's parents stage an intervention for Tori.
Commander Perry notifies the Intelligence unit that Pulpo has been released to help track down a dangerous cartel leader. This doesn’t sit well with our team as he kidnapped one of their own and no love is lost between sides. Meanwhile, Ruzek gets some difficult news as a blast from Lindsay’s past comes back, giving us a glimpse at where she came from. Voight reminds her that she’s come too far to screw it up. At the same time we learn something about Jin that is bound to be a problem.
Boyce decides to cancels the annual bake sale after taking on a healthier lifestyle.
Mel has everything she needs for the perfect wedding after a close friend unexpectedly calls off her nuptials; Lennox helps Ryder construct an untruthful resume.
Tessa struggles with the budget while planning Lisa and Malik's wedding; June warns Tessa to stay away from Ryan; Malik turns to George when his family decides to boycott the wedding; Sheila gives Lisa advice.
Banished to Tonga to live with his uncle, 14-year-old Jonah is causing more trouble than ever. His dad takes him back to Sydney to start a new life but he quickly forms a new school gang and it's not long till trouble starts.
Jay, Gloria and Manny challenge each other to step outside their comfort zone and try something new. Mitch and Cam’s wedding is getting too big and costly so they resort to selling a couple of their prized possessions, and the kids play a joke on Phil and Claire.
The night is late and Bruce has yet to seal the deal with Jessica, so he decides to try something clever. Fab and Kacey both notice their handsome gynecologist and must decide which one of them gets to make a play for him. Liv and Ron decide to do something crazy and leave for a strip club.