Nanite activity is increasing around the world. Rex decides to go to one area for Spring Break. He befriends a lonely young woman with a secret agenda.
The Destiny has jumped into hyperspace and is now traveling through an inter-galactic void. They've also been unable to locate Eli, Chloe and Scott who have been left behind. Dr. Rush has calculated that based on their current energy consumption, the Destiny has insufficient fuel to reach the next galaxy and they are doomed to die. The engines suddenly fail however and they arrange for an expert, Amanda Perry, to come on board via the communication stones and help them out. Perry and Rush have known each other for many years but as a quadriplegic, is experiencing what...
The team investigates the remains of c. 13th-century African man found in an Medieval grave in Ipswich, England.
Drama surges at LuAnn's charity event when Jill and Alex feud. In addition, LuAnn, Kelly, Jill and Sonja bond over yoga LuAnn reflects on her taxing year Bethenny flies to Los Angeles to be with her ill father and LuAnn reenters the dating scene.
A mother thought to be grieving for the loss of her family three years ago becomes a suspect in a CSI investigation.
Liz Lemon meets her mother's old flame, while Jack Donaghy's mother, Colleen, gets tangled in his relationships with Avery Jessup and high school love, Nancy Donovan. Jenna's mother, Verna returns, while Tracy learns a lesson from his "mom".
A trio of boy-crazy, fashionista teen girls from Beverly Hills balance their personal and school lives with their work as super-spies.
Naomi puts Fife in a conflicted position when she begs him to help William's advanced ALS with his still experimental treatment. Meanwhile Violet and Amelia treat a woman with a brain tumor who has to choose between life or quality of life, and Sheldon decides to officially throw his hat into the ring for Charlotte's affection
Bailey preps the team with mandatory sensitivity training prior to admitting a 700-pound patient with compounded medical issues, and the case proves to be challenging in every sense of the word. Meanwhile Derek has to come face to face with a former patient's husband in a wrongful death deposition, and spending time with a heart patient's daughter opens up some old wounds for Cristina.
A cabin burns down in the woods revealing two bodies - one of a modern-day witch and one from the days of the Salem Witch Trials - leading Booth and Brennan into the world of Wicca to find a killer. Meanwhile, when Hodgins' reckless driving gets him and Angela arrested and thrown in jail, Sweets and intern Clark Edison step into unfamiliar territory to help out the team.
Leslie hosts a late-night shift for a local telethon, and lands former Indiana Pacer Detlef Schrempf as a celebrity guest. Meanwhile, Mark has big plans for his relationship with Ann.
Crowley tells Bobby he will give him the location of Death, the fourth horseman, in exchange for his soul. Knowing Sam and Dean need that fourth ring to stop the Apocalypse, Bobby reluctantly agrees. Sam and Dean confront Pestilence, but he unleashes a deadly virus upon them, so Castiel must intervene on their behalf. Dean has a meeting with Death to discuss Lucifer, and an unholy alliance is formed at a very high price for Dean.
A kidnap drama on the ocean and relationship tremors below decks rock Hammersley as she sails the Coral Sea.
Sensing that he is in danger, a hero makes a bold move to save himself by fooling the entire tribe. Meanwhile, a vicious power struggle emerges in one alliance and two of the strongest villains find themselves pitted against one another.
InNoyo County, Washington, Peter stumbles across a grisly murder with ties to Newton and First Wave. He is forced to team up with a suspicious sheriff to get to the heart of the case. Meanwhile, Walter has trouble functioning without Peter, and worries he will be sent back to the mental institute.
Patrick Jane and the CBI team investigate the death of a mathematical genius by a gun-wielding clown.
Isobel returns to town and stuns Alaric with her attitude and her demands that he arrange a meeting with Elena. When mother and daughter finally meet, Isobel refuses to answer most of Elenas questions, but reveals that she will stop at nothing to find the mysterious invention Johnathan Gilbert has been searching for. Isobels dangerous actions lead Stefan, Damon and Bonnie to step in and help Elena deal with the situation.
Demetri investigates a murderer who is targeting people that have escaped their futures, and Mark agrees to find Simon's sister. Nicole finds Keiko, the woman in Bryce's flashforward. The FBI close in on Suspect Zero.
The sexual tension between Jeff and Britta becomes a hot topic among the study group. Meanwhile, what starts out as a simple contest for a chance at early class registration turns the peaceful campus of Greendale Community College into an all-out war zone. Friendships are tested, as only one student can be victorious.