When Sam sees a litter of puppies being born, he worries he might not be able to handle the birth of his own child.
House and the team try to diagnose a man living with severe, chronic pain; Thirteen and Foreman explore their complicated relationship; Cuddy discovers that caring for her baby leaves her with little time to run the hospital.
As the threat of terrorism escalates, Jack Bauer is forced to take matters into his own hands to avert the imminent crisis facing the country. Meanwhile, lives are on the line as conflicted Agent Renee Walker copes with the volatile investigation, and FBI honcho Larry Moss is forced to keep a closer eye on his team as the nation's security is in jeopardy. At the White House, international stakes are raised and the First Gentleman proceeds with his personal mission.
Lily and Marshall try to continue their airport reunion tradition. Barney and Ted offer to keep MacLaren's open during a blizzard so they can meet up with some college girls.
Lucas and Julian have a difficult time finding the right director for their movie. Meanwhile, a present from Lucas confuses Peyton and Brooke battles with romantic complications.
Pat's BBQ (Salt Lake City, Utah) • Blow Fly Inn (Gulfport, Miss.) • Tune-Up Cafe (Santa Fe, N.M.) Guy Fieri uncovers some places the regulars keep piling into: In Santa Fe, a little café serving El Salvadoran specialties; In Salt Lake City, a barbeque joint where folks line up for the house special -- burnt ends. And on the Mississippi coast, a joint on stilts where they re doing Creole favorites.
Following workers at the Pennsylvania SPCA, which rescues more than 10,000 animals each year, including domestic pets, and exotic and dangerous creatures.
Eternally-single Erica brings best friend Ethan to pose as her boyfriend at her high school reunion. She begins to understand the source of her relationship with men by revisiting the loss of her virginity.
The students are stressed out as they find out who was accepted and who didn't make the cut for early admission to Yale. Meanwhile, Serena bonds with Rachel, her Shakespeare teacher, who is unaware of what Blair has in store for her following receiving her first B; Chuck finds an unlikely ally in his feud with Jack; and Nate and Vanessa have a romantic evening together.
Judith is pregnant with a baby girl and Alan is convinced he is the father.
When a murder occurs during a horse race, Horatio discovers that Ryan has a personal connection to the case.
Shane tries to deal with her betrayal to Jenny as they both attempt to figure out their feelings for one another. Shane awkwardly tries to apologize to Jenny, who responds by threatening to evict Shane from her house. Meanwhile, Bette and Tina get worried when Angelica comes down with a fever which gradually gets worse. Alice and Tasha cannot decide whether to break up or stay together since their different views on life strain their romance to the breaking point. Elsewhere, Helena and Kit celebrate after taking over SheBar nightclub and formally rename the place, 'HIT!'
When Eli Scruggs (Beau Bridges), the neighborhood handyman, passes away, the residents of Wisteria Lane realize how much he affected their lives.
Bret and Jemaine fire Murray for neglecting them in favour of the Crazy Dogggz and almost immediately they receive an offer to write a jingle for a commercial. Meanwhile Murray's fortunes reverse after he discovers that the Crazy Dogggz big hit is a rip-off of a 1990s Polish song.
Suburban mother and wife Tara Gregson does her best to lead a normal life while dealing with multiple personalities that include a spirited teenager called "T," a Vietnam vet named "Buck," and the perennial 1950's-style housewife, "Alice."
Grylls wraps up warm as he heads to the frozen wastelands of North Canada. He goes underground to search an abandoned mine, and he takes to some fast moving water.