Mona and Dee Dee are half-sisters with the same father who didn't really know each other when they were little and are complete opposites, but as adults they live in the same apartment building and at least try to bond.
Lynn is hesitant regarding Jennifer's marriage plans; however, due to Jennifer's fragile state of mind, agrees anyway. Meanwhile, Toni and Todd continue to struggle with their marriage.
Manny's still foggy on what exactly it was that happened at Peter's party the night before. She knows she made a pretty racy video but Peter will erase everything... or so he says.
Investigating his father's claim that a British group set him up, Michael goes to Wee Britain and is smitten with a beautiful woman named Rita. Lindsay attempts to seduce the new family attorney, and Gob goes to extremes to avoid his newly discovered son.
Michael creates a lockdown by sabotaging the air conditioning in order to execute his breakout plan properly, and unintentionally causes a riot that gets Sara into huge trouble. Meanwhile, an ex-con is blackmailed into seeing to that Lincoln is killed.
Ben is thinking about flying out to Oregon to meet with Naomi about saving his marriage. However, his family is dead set against it, especially Lydia.
All outside noise is drowned out as a popular song is continuously played very loud, and only in Allison's head. The song gives Allison clues to the whereabouts of a missing coed.
In a desperate attempt for a second date, Ted invites Robin to a party he is throwing. However, she doesn't show up and he keeps throwing parties in the hopes she will finally arrive.
Uncle Andy acts foolish at a ceremony for Judah. Shane gets in trouble again. Celia and Dean duke it out. Nancy finds out who it is that has been delivering pennies onto her car and fountain and she deals with them. Andy and Doug team up to bring more trouble into Nancy's home while trying to flush out the infestation of a rat. Nancy turns down an interested single father. And Uncle Andy exposes too much of himself yet again.
Jake gets suspended from school after drawing an offensive picture of a girl in his class that has large breasts. Meanwhile, Charlie is asked to watch over Alan's chiropractic office after pulling an all-nighter.
Two plastic surgeons--one a dedicated family man and one an unscrupulous playboy--strive to maintain their business whilst having to work their way through numerous hardships ranging from personal to clients with criminal connections.
Eric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
The life, or lack thereof, of a proprietor of a gas station, which is the only stop for miles around and a hub of action on the Prairies.
How Could Bunny Scout Ruby Earn Her Trading Bunny Scout Badge?/Max Has a problem about what chicks are./Max has a new chick that wonders all around East Bunny Hop
Doug and Carrie consider marriage counseling while Arthur wants to direct (and act in) a play at the senior center.
Derek manages to insult his new step-sister, making Casey clumsily fall down at school and earn the nickname Klutzilla. And it just keeps getting worse as Casey continues her klutz streak. Finally Derek realizes something, besides his rude behavior, that might be making Casey fall and decides that helping her reputation will help his, as it's bound to get out that they are newly step-sibs.
The new neighbors, the Applewhites have moved in. Gabrielle, Lynette, and Susan attempt to comfort Bree while Rex's mother arrives on Wisteria Lane for his funeral. Meanwhile Mike and Susan deal with Zach while Gabrielle struggles with the two men in her life.
Picks up where the last episode left off. Meredith attempts to work with Addison Shepard. George is pimped out to relay the hospital gossip back to Webber. Meredith and Cristina relate at Emerald City Bar about what dating their respective attendings is like. Cristina ponders her relationship with Burke while trying to make a decision. Meredith is devastated by the latest blow to her love life. Meanwhile, Joe the bartender collapses.
Never one to miss the opportunity to make a quick buck, Homer cashes in on Maggie's bout of chicken pox. He decides to host a Pox Party and charges parents to infect their children.
Four days after the Democratic convention, Josh begins to staff up the Santos campaign. With Santos and Leo effectively strangers - and Leo not an experienced campaigner - adjustments of roles and responsibilities are required in order to deliver a strong and consistent message. The White House prepares to launch the military Space Shuttle on its rescue mission to the Space Station amidst growing suspicion that proof of its existence was deliberately leaked by someone in the Administration. The Republicans offer Bartlet a concession on an education bill in an attempt ...