Christine's former marriage counselor comes into the gym, leading to some awkward moments between the two women. When Christine mentions this to Richard, his cryptic reaction leads her to question whether it was in the counselor's best interest to encourage their divorce. Meanwhile, Matthew finds Christine's wedding video in a box of old photo albums, and Christine takes a trip down memory lane.
Simon and Rose prepare for their wedding day, despite speculation that it is not the right decision. Annie and Eric go through countless scenarios in their minds as they reflect on how the wedding will actually turn out.Meanwhile, Rose's former boyfriend shows up unexpectedly. Ruthie considers studying in Scotland over the summer. Kevin, Lucy, Matt, and Sarah all have life-changing news, if only they can find the perfect time to share it with the family...and the surprises don't stop there!
After Steve shows a lack of interest in Stan's job, Stan replaces him with Barry, Steve's malicious friend. Barry frames Steve to eliminate him from the household, but when Steve discovers Barry's weakness, he relies on his CIA skills to save the family. Meanwhile, Roger takes an impressive keg-stand and uses it to become a fraternity brother.
The escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, while keeping America safe.
Bill wants to throw a party to celebrate Don's plans of getting a fourth wife but Nicki's massive credit card debt weighs heavily on his mind. Pam's friend attempts to make his moves on Margie, but she is preoccupied with wanting to know more of how she became a part of the Henrickson family.
Peter wants to top Joe, who just built a new home theater system, so he starts to build a multiplex in his backyard. In doing so, he discovers an Indian burial ground. He finds an Indian chief's skull and the Griffin house becomes haunted. Stewie gets sucked into the television and strange events follow as they try to get Stewie back from the poltergeist.
C.J. and Will both face uncertain futures as Bartlet and his staffers prepare to leave the White House to make way for the Santos administration.
Trinity is in danger of failing grade 6. Ricky comes to the rescue. Bubbles reveals that he has a fear of chickens.
Logan and Barek investigate a series of home invasions that result in grisly murders and their search leads them to local foster mother Chesley Watkins who had a series of young men going in and out of her home throughout the years. One of the young men involved in the home invasions was one of her boys, and while trailing the young man, Logan shoots a suspect who was brandishing a weapon at himself and Barek. When the suspect turns out to be a cop, Logan finds himself in the hot seat, and Barek sticks up for her partner, knowing that the truth is on their side. The investigation leads to Watkins as a suspect, and Logan is forced to deal with memories from his own past as Watkins plays on the weaknesses she sees.
When a new witness steps forward, Lilly and the team are prompted to re-open the 1984 shooting of a respected and beloved ER doctor who had a secret he had been hiding from his family.
Mickey and his friends Minnie, Donald, Pluto, Daisy, Goofy, Pete, Clarabelle and more go on fun and educational adventures.
In an attempt to destroy the reputation of the Charmed Ones, Billie & Christy resort to trying to make the magical community see that the Halliwells only care about themselves. Meanwhile, Phoebe begins to lust after Coop; Paige cannot hear her charges' call for help; Piper becomes the perfect 1950s housewife.
Bree and Andrew finally reach an impasse in their relationship as tension has finally reached a critical point. Meanwhile, Ed finally fires Tom with the pressure from his wife. Lastly, Edie's private detective begins to uncover numerous details of Karl and Susan's relationship as of recently. Gabrielle is having a tough time keeping her servant in the country.
Marge goes on a cleaning frenzy before the housekeeper she’s won the services of comes to the house. One spot remains and she mixes a number of toxic cleaners together to tackle the job. The noxious mixture knocks her out and she wakes up suffering from amnesia. Marge is taken home and the family tries to bring back her memory. She starts to get back memories of her children and other insignificant things, but when it comes to remembering her husband, nothing he does seems to jog her memory. When he can’t get her to remember him, he tries to win her all over again, especially after Patty and Selma get her back out on the dating scene.
Bob is trying to prevent a rain of concentrated sulfuric acid that would destroy Mexico City. Homeland Security suspects two American scientists of preparing a bio-terrorist attack against the United States President and order David and Caroline to investigate.
Huff's father decides that he will extend his stay, and some family members feel he is wearing out his welcome. Lena asks Huff to address her alternative psychiatric therapy students. Byrd offends some people with his latest art project. Meanwhile, Russell ends up going on a drug-fueled bender.
Paulie finds public opinion turned against him after an amusement ride accident, while Chris tries to start a new life as a husband and father.
The staff attends to an intern from another hospital who has short-term memory loss. This intern, named Marshall, also has caused a car accident that involved a married couple, their unborn baby and the woman's parents who the staff are also treating. The pregnant woman is named Melanie and she will die but her baby may survive. One of the female interns meets up with a woman from her past who is planning on having a family of her own. Cristina is in a good mood although Alex, Izzie, George, and Meredith are having problems but in the meantime Burke hasn't forgiven Cristina for her late night faux pas. Meredith and Izzie are making fun of Callie's household habits and George and Callie are having a fight because of George's roommates. Addison is continuing to own Alex and he's upset about it. Denny has an outburst at Izzie and Derek has an outburst at Meredith.